The phytochemical profile and identification of main phenolic compounds from the leaf exudate of<i> Aloe secundiflora</i> by high‐performance liquid chromatography–mass spectroscopy

Waihenya, Rebecca; Kayser, Oliver; Hagels, Hansjörg; Zessin, Karl H.; Madundo, Mtambo; Gamba, Nkwengulila

doi:10.1002/pca.682

Cited by 48 publications

(27 citation statements)

References 21 publications

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“…10 It contains aloenin which has antiviral (Waihenya et al, 2005) and nematicidal activity against Ascaridia galli ( Kaingu et al, 2013) It contains anthrones (aloenin, isobarbaloin, aloenin B and barbaloin), chromones and phenylpyrones (Rebecca et al, 2003).…”

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confidence: 99%

Ethnobotanical survey and threats to medicinal plants traditionally used for the management of human diseases in Nyeri County, Kenya

Kamau¹,

Mbaabu²,

Mbaria³

et al. 2016

TANG [HUMANITAS MEDICINE]

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In Kenya, traditional knowledge on herbal medicine has remained a mainstream source of maintaining wellbeing for generations in many communities. However, the knowledge has been eroded in the course of time due to sociocultural dynamics virtually advanced by Christianity and formal education especially in the Kikuyu community. The study documented current ethnobotanical knowledge and threat to the traditional knowledge on medicinal plants among the Kikuyu community. A survey was carried out in Mathira, Tetu, Kieni, Othaya, Mukurweini, and Nyeri Town constituencies. Thirty practicing herbalists were purposively sampled; 5 per constituency. Data was obtained through semi -structured questionnaires and analyzed both qualitatively and quantitatively. A total of 80 ailments treated using 111 medicinal plant species distributed within 98 genera and 56 families were documented. Prevalent communicable diseases treated using herbal medicine included; gonorrhea (17.5%), malaria (15%), respiratory infections (12%), colds (10%) and amoebiasis (10%). Non-communicable diseases were; joint pains (11.1%), ulcers/hyperacidity (8.7%), high blood pressure (8.7%), intestinal worms (11.1%) and arthritis/gout (10%). Frequently harvested plant materials were; roots, barks and leaves. The study concluded that, traditional medicine practitioners in Nyeri County possessed wide knowledge of herbal medicine but this knowledge was on the verge of disappearing as it was largely a preserve of the aged generation. The study recommended massive campaign about the benefits of using herbal medicine in the study area. Further pharmacological studies are recommended on the mentioned plant species aimed at establishing their efficacy and safety as well as standardization as potential drugs.

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mentioning

confidence: 99%

Ethnobotanical survey and threats to medicinal plants traditionally used for the management of human diseases in Nyeri County, Kenya

Kamau¹,

Mbaabu²,

Mbaria³

et al. 2016

TANG [HUMANITAS MEDICINE]

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“…For the determination of low levels of barbaloin in aloe-based products, chromatography/ mass spectrometry (LC/MS) and LC with diode array detection (DAD) in the UV range (LC/UV) were developed [31] . Analytical HPLC-MS method was developed and performed for the determination of barbaloin [32] . A rapid and sensitive fluorometric method is described for the determination of barbaloin in aloe vera gum, based on complexing europium with barbaloin in a micellar solution of CTAB (cetyl trimethylammonium bromide).…”

Section: Analytical Methods Of Barbaloinmentioning

confidence: 99%

Barbaloin: A concise report of its pharmacological and analytical aspects

Patel

Tahilyani³

2012

Asian Pacific Journal of Tropical Biomedicine

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“…The leaf exudate of this species has found ethno-veterinary use for treatment of bacterial diseases and parasites and in management of viral diseases. In poultry for example the exudates has been extensively used as prophylaxis for Newcastle diseas and as therapeutic for fowl typhoid, coccidiosis and other enteric conditions (Waihenya et al, 2003). Analytical High Performance Liquid Chromatography-Mass Spectropy (HPLC-MS) studies of the exudates have shown that it consists of a mixture of phenolic compounds or aliphatic compounds (Waihenya et al, 2003).…”

Section: Research Scholarshipmentioning

confidence: 99%

“…In poultry for example the exudates has been extensively used as prophylaxis for Newcastle diseas and as therapeutic for fowl typhoid, coccidiosis and other enteric conditions (Waihenya et al, 2003). Analytical High Performance Liquid Chromatography-Mass Spectropy (HPLC-MS) studies of the exudates have shown that it consists of a mixture of phenolic compounds or aliphatic compounds (Waihenya et al, 2003). This research was carried out to assess the anthelmintic activity of Aloe secundiflora extracts in vitro using the nematode parasite Ascaridia galli in larval development assays.…”

Section: Research Scholarshipmentioning

confidence: 99%

Efficacy of Aloe secundiflora Crude Extracts on Ascaridia galli in Vitro

Kaingu¹,

Kibor²,

Waihenya³

et al. 2012

SAR

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Aloe secundiflora Synonym: Aloe floramaculata, Aloe marsabitensis, Aloe engleri belongs to the family Asphodelaceae. Aloe leaf gel and Aloe exudates are the main components. The gel is derived from parenchytomous cells while exudates are derived from the inner epidermal layers. The gel consists of mainly polysaccharides while the exudates consists of a mixture of phenolic compounds mainly athrones, chromones and phenyl pyrones. Leaf components of Aloe have been credited for antibacterial, antifungal and antiviral and anthelmintic medicinal properties. The effectiveness of Aloe secundiflora extracts on the most prevalent nematode of chicken Ascaridia galli was conducted in vitro. The results of this study indicate that Hexane, Ethylacetate, Acetone, Methanol and chloroform extracts were found active in hindering the development of Ascaridia galli eggs to larval stage three (L 3 ), and this was dependent on the concentration of the crude extract. The lowest concentration of the various extracts (5 mg/ml) had an inhibition percent (IP), 75.52%, 79.60%, 87.21%, 86.13% and 43.6% respectively. The highest concentration of the extracts was (50 mg/ml), at this level the inhibition percent was found higher than in the lowest extracts concentrations i.e., 91.84%, 97.55%, 100%, 99.46% and 91.29% respectively. Aloe secundiflora extracts therefore have inhibitory effects on the Ascaridia galli larval development in vitro. Phytochemical tests on the extracts revealed the presence of various chemical compounds.

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The phytochemical profile and identification of main phenolic compounds from the leaf exudate of Aloe secundiflora by high‐performance liquid chromatography–mass spectroscopy

Cited by 48 publications

References 21 publications

Ethnobotanical survey and threats to medicinal plants traditionally used for the management of human diseases in Nyeri County, Kenya

Ethnobotanical survey and threats to medicinal plants traditionally used for the management of human diseases in Nyeri County, Kenya

Barbaloin: A concise report of its pharmacological and analytical aspects

Efficacy of Aloe secundiflora Crude Extracts on Ascaridia galli in Vitro

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