2009
DOI: 10.1016/j.ijdevneu.2009.08.002
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The pineal volume: a three‐dimensional volumetric study in healthy young adults using 3.0 T MR data

Abstract: It is usually difficult to distinguish small pineal tumors via routine or enhanced magnetic resonance (MR) scan. The knowledge of normal pineal size is helpful to detect small pineal lesions, while very few true volumetric data of pineal glands have been reported. Therefore, we obtained the accurate reference range of normal pineal volumes in 112 individuals aged 20-30 years recruited randomly from a healthy community sample. Transverse and sagittal 3.0T magnetic resonance data were obtained using three-dimens… Show more

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Cited by 39 publications
(34 citation statements)
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“…The height, width, and length of the pineal gland is small (3.8, 4.27 and 4.8 mm) compared to the morphometric findings reported by Sun et al [2] (3.85, 6.92, 6.64 mm). Compared to the subject's age, his pineal volume is less; when compared to age and corresponding volume of healthy young adults and the circumference of head, the pineal volume is less in size.…”
Section: Discussioncontrasting
confidence: 63%
See 1 more Smart Citation
“…The height, width, and length of the pineal gland is small (3.8, 4.27 and 4.8 mm) compared to the morphometric findings reported by Sun et al [2] (3.85, 6.92, 6.64 mm). Compared to the subject's age, his pineal volume is less; when compared to age and corresponding volume of healthy young adults and the circumference of head, the pineal volume is less in size.…”
Section: Discussioncontrasting
confidence: 63%
“…An extensive study conducted on pineal volume in healthy young adults by [2] reports that the mean pineal volume in the case of male adults with no cysts was estimated to be 89.21 ± 28.78 mm 3 and the true pineal volume in healthy adults was reported to be 94.2 ± 40.65 mm 3 . A study pertaining to the evolving size of the pineal gland [1] reports that the size of the pineal gland was 26.9 ± 12.4 mm 3 (mean ± SD) in subjects with age greater than 2 years, and in patients with age ranging from 2 to 20 years the volume was observed to be 56.6 ± 27.6 mm 3 (mean ± SD).…”
Section: Previous Workmentioning
confidence: 99%
“…In contrast, another study also among young participants found a cyst prevalence of only 25% (Sun et al, 2009). The estimation of cysts may depend on the method used.…”
Section: Discussionmentioning
confidence: 89%
“…In this same study the mean pineal volume was found to be smaller among subjects with untreated insomnia (49 mm 3 ). In a study by Sumida et al the average pineal volume of 57 mm 3 among 223 subjects remained stable in the age group 2–20 years old (Sumida et al, 1996) and Sun et al reported a mean pineal volume of 95 mm 3 among 66 healthy males with mean age 24.7 years (Sun et al, 2009). Thus, the caliper method seems to result in overall smaller pineal volumes compared with our and others‘ methods.…”
Section: Discussionmentioning
confidence: 99%
“…This observation was made possible by the recently available ultra-high-field MRI at 7 T. As shown in Fig. 2 (upper), visualization of the pineal gland was largely limited by the poor resolution of the currently available commercial scanners, such as the 1.5 and 3.0 T MRI machines [6,7]. Ultra-high-field 7 T MRI, especially with its markedly enhanced T2* imaging capability, however, allows visualization of details in the inner structures of the pineal gland ( Fig.…”
Section: Introductionmentioning
confidence: 99%