The Place of Thiothixene in the Treatment of Schizophrenic Patients

Sterlin, C; Ta, Ban; He, Lehmann; Bm, Saxena

doi:10.1177/070674377001500102

Cited by 5 publications

(4 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thiothixene is a well-known thioxanthen derivative with a piperazine sidechain. The drug has documented antipsychotic efficacy (Sterlin et al (1970), Kellam & Jones (1971), Lee & Simpson (1973)) without unwanted sedative effects. It is mainly recommended for long-term treatment of chronic psychotic conditions where an unspecific sedative effect is not wanted.…”

mentioning

confidence: 99%

Controlled trial of penfluridol and thiothixene in the maintenance treatment of chronic schizophrenic syndromes

Jacobsson

Knorring

Mattsson

et al. 1976

Acta Psychiatr Scand

View full text Add to dashboard Cite

In a controlled trial of penfluridol and thiothixene as maintenance drugs in patients with chronic schizophrenic syndromes, some improvement over previous neuroleptics was seen with both drugs. This improvement was mainly evident in variables concerned with participation in social activities as assessed with the S-scale and by ward behaviour. The drug dosages necessary were very low and gave few and easily manageable side-effects. There was no significant difference between penfluridol and thiothixene. Penfluridol has the clear practical advantage of being the only long-acting drug for oral administration so far available.

show abstract

mentioning

confidence: 99%

Controlled trial of penfluridol and thiothixene in the maintenance treatment of chronic schizophrenic syndromes

Jacobsson

Knorring

Mattsson

et al. 1976

Acta Psychiatr Scand

View full text Add to dashboard Cite

show abstract

“…Previous studies have shown thiothixene to be efficacious in relieving the symptoms of acute schizophrenic patients (1)(2)(3)(4)(5)(6).…”

Section: Introductionmentioning

confidence: 99%

Double-Blind 1 rial of Thiothixene and Chlorpromazine in Acute Schizophrenia

Rickels¹,

Byrdy²,

Valentine³

et al. 1978

Int Pharmacopsychiatry

View full text Add to dashboard Cite

show abstract

“…A favourable feature of thiothixene is that it causes side effects and adverse reactions to a much smaller extent than other neuroleptics (3,10,22).…”

mentioning

confidence: 99%

“…Under thiothixene treatment these patients become more animated, they achieve more ac tive interest in, and better emotional contact with, the environment (3,13,14,22).…”

mentioning

confidence: 99%

Effect of Thiothixene upon the Higher Nervous Activity in Chronic Schizophrenics

Saarma¹,

Saarma²,

Sild³

et al. 1974

Int Pharmacopsychiatry

View full text Add to dashboard Cite

The clinical effects of thiothixene and its action upon the HNA have been investigated in a sample of 22 chronic schizophrenic patients (mean duration of the disease 9.6 years). In three patients there was a good, and in nine patients there was a moderate, clinical improvement. In HNA there was a marked improvement of the stability of excitatory process, of the equilibrium of excitatory and inhibitory processes and of internal inhibition. Some of the HNA parameters reflecting the intensity of transmarginal inhibition were found to be of prognostic value.

show abstract

The Place of Thiothixene in the Treatment of Schizophrenic Patients

Abstract: The drugs used in this study were supplied through the courtesy of Pfizer Limited,

Cited by 5 publications

References 3 publications

Controlled trial of penfluridol and thiothixene in the maintenance treatment of chronic schizophrenic syndromes

Controlled trial of penfluridol and thiothixene in the maintenance treatment of chronic schizophrenic syndromes

Double-Blind 1 rial of Thiothixene and Chlorpromazine in Acute Schizophrenia

Effect of Thiothixene upon the Higher Nervous Activity in Chronic Schizophrenics

Contact Info

Product

Resources

About