The point of EUS-guided liver biopsy

Schembre, Drew

doi:10.1016/j.gie.2020.12.007

Cited by 2 publications

(4 citation statements)

References 17 publications

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“…www.co-gastroenterology.com acquisition of liver biopsy specimens during endosonography, the ability to perform several needles passes with single puncture, and multilobar sampling regardless of body habitus. It is also faster than TJLB and results in significantly less pain compared to either PCLB or TJLB [11,12]. A recent meta-analysis assessed the adequacy of liverspecimens obtained by PCLB, TJLB, andEUSLB by assessing the number of complete portal triads (CPT), total specimen length (TSL), and length of the longest piece (LLP) of liver tissue [13 & ].…”

Section: Key Pointsmentioning

confidence: 99%

“…EUSLB presents a number of advantages, including real-time imaging and localization, acquisition of liver biopsy specimens during endo-sonography, the ability to perform several needles passes with single puncture, and multilobar sampling regardless of body habitus. It is also faster than TJLB and results in significantly less pain compared to either PCLB or TJLB [11,12].…”

Section: Introductionmentioning

confidence: 99%

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Endohepatology – current status

Edelson

Mitchell

Rockey

2022

Current Opinion in Gastroenterology

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Purpose of reviewThis article discusses the most recent studies regarding the emerging field of endohepatology – the use of diagnostic and therapeutic endoscopic tools for the management of patients with liver disease and portal hypertension.Recent findingsNew research has shown that liver biopsy specimens obtained by each Endoscopic ultrasound (EUS)-guidance, the percutaneous approach, and the transjugular approach contained sufficient portal triads to adequately analyzed by experienced pathologists – suggesting that any of these routes of liver biopsy is clinically acceptable; further, all had similar rates of adverse events. An initial prospective study showed that EUS guided portal pressure measurement was safe, effective, and accurate. A recent metanalysis showed that EUS-guided cyanoacrylate injection and coil embolization was statistically more efficacious and with less complications than EUS guided cyanoacrylate injection and EUS guided coil injection alone, suggesting that combination therapy appears to be the preferred approach for gastric varices (GV) bleeding. A prospective study evaluating focal liver lesions showed that the use of artificial intelligence had up to 100% sensitivity and 81% specificity for identifying malignant focal liver lesions.SummaryEUS guided liver biopsy is safe and enables accurate diagnosis of underlying liver disease. EUS guided portal pressure measurement is also safe and is accurate. Combination therapy of EUS guided cyanoacrylate injection and coil embolization is more efficacious and has less complications than injection or coil therapy alone when used for GV bleeding. Artificial intelligence is highly sensitive and specific when used in conjunction with EUS in the diagnosis of malignant focal liver lesions. Endohepatology is a rapidly expanding field with great potential.

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Section: Key Pointsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Endohepatology – current status

Edelson

Mitchell

Rockey

2022

Current Opinion in Gastroenterology

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“…The current literature supports the feasibility of endo‐hepatology as a diagnostic modality with an acceptable safety profile and high technical success rate. However, it is important to note that the literature is driven by experience from tertiary care hospitals and as a result, community‐based studies are required to establish its broad utility and reproducibility 12 …”

Section: Diagnostic Utility Of Eusmentioning

confidence: 99%

“…However, it is important to note that the literature is driven by experience from tertiary care hospitals and as a result, community-based studies are required to establish its broad utility and reproducibility. 12…”

Section: Eus-guided Lbmentioning

confidence: 99%