“…Eleven studies described a median proportion of 11% of limbs (range, 5%-67%) presenting with acute ischemia. 24,26,27,30,33,36,37,41,42,45,49 A median proportion of 38.25% of patients (range, 0%-100%) diagnosed with bilateral PAES was described in 26 studies. In 12 of 30 studies, a median proprtion of 17.5% of limbs (range, 6%-31%) diagnosed with PAES were asymptomatic, whereas this proportion was unclear in seven studies.…”