The Possibility of Postoperative Cognitive Dysfunction in Obstetric Anaesthesia Following Caesarean Section

Ghosh, S.

doi:10.1097/01.aoa.0000426069.33714.9f

Cited by 1 publication

(3 citation statements)

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“…The steroid concentration in umbilical cord is less in babies born by CS compared to those born by VD; it is also lower in babies born by elective CS compared to emergency CS (26,27). Psychological stress is more likely to occur after emergent CS than an elective one (15). Subsequently, the psychological stress is related to a sense of loss, altered identity, postpartum depression, poor connection with the newborn, and emotions of aggressiveness and rage (28).…”

Section: Discussionmentioning

confidence: 99%

“…To calculate sample size, we compared early POCD occurrence between cases after elective and those after emergent CS under GA, as it was the primary outcome of the study. As reported in a previous publication (15), we assumed that emergent CS causes cognitive dysfunction in at least 10 patients. The minimum calculated sample size was 24 patients in each arm to reject the null hypothesis with 80% power at α = 0.05 level using Student's t-test.…”

Section: Sample Sizementioning

confidence: 99%

“…Rapid recovery of patients who have been under GA and their returning to their pre-anesthesia condition mentally are major goals for anaesthesiologists (13,14). Thence, evaluation of the cognitive behavior preoperatively is essential since mild cognitive impairment may be worsened following a CS (15).…”

Section: Introductionmentioning

confidence: 99%

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Early Postoperative Cognitive Dysfunction in Women Undergoing Elective and Emergent Caesarian Section under General Anaesthesia: A Comparative Study

et al. 2022

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Background: Postoperative cognitive dysfunction (POCD) following cesarean section (CS) is a growing and underestimated problem with unknown mechanisms. Studies suggest that general anesthesia (GA) plays a role in the development of early POCD. Objectives: This study aimed to assess the incidence of early POCD after elective and emergent CS under GA. Methods: We assessed the difference between the elective and emergent groups regarding the mini-mental state examination (MMSE), hemodynamic effects such as mean blood pressure (MBP), and heart rate (HR). Paired t-test was applied for intragroup comparison, and Student’s t-test (or Mann–Whitney U test, as appropriate) for intergroup comparison. Results: MMSE one hour after the operation was significantly lower than preoperative MMSE in the emergent group, and the MMSE tended to return to normal values faster in the elective than in the emergent group. Moreover, we found a significantly lower MBP and higher HR (at 15, 30, and 45 minutes) in both groups compared to preoperative values. Regarding intergroup comparison, MBP (at 30 minutes) significantly decreased in the elective group compared to the emergent group. Conclusions: There was a significantly lower POCD, especially at the first hour postoperatively, in the elective CS than in the emergent CS. Elective CS might have a positive effect on the women’s health as a mode of delivery.

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