The possible DNA damage induced by environmental organic compounds: The case of Nonylphenol

Noorimotlagh, Zahra; Mirzaee, Seyyed Abbas; Ahmadi, Mehdi; Rahim, Fakher

doi:10.1016/j.ecoenv.2018.04.023

Cited by 44 publications

(15 citation statements)

References 72 publications

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“…The present review was conducted over the rearch studies published on immune and bioinformatics identification of T-cell and B-cell epitopes in the protein structure of SARS-CoV-2. In developing our systematic review (SR) protocol, preferred reporting elements for the SR statements, meta-analyses (PRISMA) and guidelines from the Cochrane Reviewer's Handbook were used (http://www.prisma-statement.org/ Extensions/InDevelopment.aspx) [9,10], Noorimotlagh et al [11].…”

Section: Methodsmentioning

confidence: 99%

Immune and bioinformatics identification of T cell and B cell epitopes in the protein structure of SARS-CoV-2: A systematic review

Noorimotlagh

Karami

Mirzaee

et al. 2020

International Immunopharmacology

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The beginning of 2020 was marked as the emergence of a COVID-19 outbreak caused by a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, there is no vaccine or approved treatment for this infectious virus so the invention of an efficient vaccine is certainly a high priority. Some studies have employed several techniques to facilitate the combination of the immunoinformatics approach and comparative genomic approach in order to determine the potential peptides for designing the T-cell epitopebased peptide vaccine using the 2019-nCoV envelope protein as a target. Via screening the bioimmunoinformatic SARS-CoV2 derived B-cell and T-cell epitopes within the basic immunogenic of SARS-CoV2 proteins, we presented a set of inferred B-cell and T-cell epitopes from the spike (S) and nucleocapsid (N) proteins with high antigenicity and without allergenic property or toxic effects. Our findings provide a screened set of epitopes that can be introduced as potential targets for developing peptide vaccines against the SARS-CoV-2 virus.

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Section: Methodsmentioning

confidence: 99%

Immune and bioinformatics identification of T cell and B cell epitopes in the protein structure of SARS-CoV-2: A systematic review

Noorimotlagh

Karami

Mirzaee

et al. 2020

International Immunopharmacology

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“…So it is certainly possible that human exposure to NP could induce reproductive toxicity as found in the rodent studies. Indeed, possible detrimental effects of NP on male fertility were systematically documented in recent review studies (Noorimotlagh et al, 2017; Noorimotlagh et al, 2018). To confirm the adverse effects of NP on human, however, the low-dose tests that reflect the levels in range similar to those found in human bodies should take precedence.…”

Section: Introductionmentioning

confidence: 99%

Adverse Effect of Nonylphenol on the Reproductive System in F1 Male Mice: A Subchronic Low-Dose Exposure Model

Kim¹,

Cheon²,

Lee³

2019

Dev. Reprod.

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Nonylphenols (NPs) are widely used industrial materials, and are considered as potent endocrine disrupting chemical. Present study was undertaken to clarify the effect of subchronic low-dose NP exposure to F1 generation male mice. Mice were divided into 2 groups; (1) CON, control animals and (2) NP-50 (50 μg/L), animals were treated with NP via drinking water. NP exposures were continuously conducted from parental pre-mating period until the postnatal day (PND) 55 of F1 offsprings. Mice were sacrificed on PND 55 and the tissue weights were measured. The initial body weights (at PND 21) and terminal body weights (PND 55) of the NP-50 animals were significantly lower than those of control animals ( p< 0.05). NP exposure induced a significant increase in the absolute weight of the testes ( p< 0.05). Conversely, the NP exposure caused significant decrease in the absolute weights of the epididymis ( p< 0.01), prostate ( p< 0.05) and seminal vesicle ( p< 0.05). Histopathological studies revealed that NP-treated animals exerted decreased seminiferous tubule diameters, reduced luminal area, and lower number of germ cells. Also some sloughing morphologies in the tubules were observed. In the caudal epididymis, fewer mature sperms and swollen epithelial cells were found in the NP-treated group. Our results confirmed that the subchronic low-dose NP exposure altered some male parameters and induced histopathological abnormalities in testis and epididymis of F1 mice. Since the NP dose used in this study is close to the average human daily NP exposure, our results could provide practically meaningful understanding of adverse effect of EDC in human.

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“…The chlorine ion (Cl − ) and its transient form, the hypochlorous radical (HOCl %− ) (rate constant 6.1 × 10 9 s −1 ), are converted together in the series of reactions described in Eqs. (9) and (10). The chlorine ion (Cl − ), due to its high reaction rate constant (4.3 × 10 9 M −1 s −1 ), efficiently scavenge HO % radicals.…”

Section: Cwpo Process On Bpa Degradation In Aqueous Solution and Its mentioning

confidence: 99%

“…Therefore, as described in Eq. (10), when the solution pH decreases, the formation of the chlorine radical (Cl % ) increases by the protonation reaction, thus increasing the HO % radical scavenging effect (by Eq. (9)).…”

Section: Cwpo Process On Bpa Degradation In Aqueous Solution and Its mentioning

confidence: 99%

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Magnetic titanium/carbon nanotube nanocomposite catalyst for oxidative degradation of Bisphenol A from high saline polycarbonate plant effluent using catalytic wet peroxide oxidation

Mirzaee

Jaafarzadeh

Gomes

et al. 2019

Chemical Engineering Journal

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The saline polycarbonate wastewater was treated by catalytic wet peroxide oxidation. • The magnetite TNT/CNT nanocomposite was developed as CWPO catalyst. • The complete BPA, 68.78% of COD and 47.14% of TOC reduction was obtained in CWPO. • The reusability of the catalyst shows with slight decline after 4 consecutive runs. • The biodegradability of treated PCW using CWPO process was improved significantly.

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The possible DNA damage induced by environmental organic compounds: The case of Nonylphenol

Cited by 44 publications

References 72 publications

Immune and bioinformatics identification of T cell and B cell epitopes in the protein structure of SARS-CoV-2: A systematic review

Immune and bioinformatics identification of T cell and B cell epitopes in the protein structure of SARS-CoV-2: A systematic review

Adverse Effect of Nonylphenol on the Reproductive System in F1 Male Mice: A Subchronic Low-Dose Exposure Model

Magnetic titanium/carbon nanotube nanocomposite catalyst for oxidative degradation of Bisphenol A from high saline polycarbonate plant effluent using catalytic wet peroxide oxidation

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