The possible effects of the Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 on the practice of fertility preservation in female cancer patients in Japan

Abstract

Purpose:In 2017, the first guidelines for fertility preservation in cancer patients were published in Japan. However, the impact of the guidelines remains unknown.Therefore, the authors conducted a nationwide survey on cryopreservation procedures in the period from shortly before to after publication of the guidelines (2016-2019) and compared the results with our previous survey (2011)(2012)(2013)(2014)(2015). The authors also surveyed reproductive specialists' awareness of the guidelines and implementation problems. Methods:The authors sent a questionnaire to 618 assisted reproductive technology facilities certified by the Japanese Society of Obstetrics and Gynecology. How to cite this article: Kunitomi C, Harada M, Sanada Y, et al. The possible effects of the Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 on the practice of fertility preservation in female cancer patients in Japan.

Survey on the implementation status and reproductive outcomes of oocyte and ovarian tissue cryopreservation in Japan: Historical comparison with nationwide surveys

“…The number of FPs performed, number of pregnancies and number of live births in this survey were compared with those in studies conducted at different time periods. [4][5][6]…”

“…Figure 3 is also transition in the number of OTC cases, including OTTs, between the present and previous studies. [4][5][6] A report on the number of OC shows that from 2001 to 2005, 249 cases of OCs were performed on patients with hematological diseases at facilities registered with A-PART (the Japan Association of Private Assisted Reproductive Technology Clinics and Laboratories). And there were 812 cases of OC performed between 2006 and 2016 in Japan.…”

“…Furthermore, even when citing other literature, a total of 1943 cases of OC were calculated, indicating that there were more than 50 cases of ETs (Table 6). 5,6 Additionally, the number of JSOG-registered facilities that can perform OC has increased significantly (from 63 facilities to 150 facilities).…”

“…The purpose of this research was to evaluate the changes over time in the performance and outcomes of OC and OTCs in Japan, by comparing the results of the current study with those of previous surveys. [4][5][6]…”

Follicle development and its prediction in patients with primary ovarian insufficiency: Possible treatments and markers to maximize the ability to conceive with residual follicles

“…However, depending on their clinical conditions, such as the time left before treatment for the primary disease, not all patients can preserve their oocytes. [7][8][9][10][11][12][13][14][15] Certain situations may require use of the remaining ovarian follicles to attempt pregnancy, not only in cases of unpredictable POIs but also in iatrogenic cases.…”