The Possible Role of Torque teno Virus in Kidney Allograft Recipients in a Sample of Iraqi Patients

Abstract

Background: The use of immunosuppressive medications remains the most important challenge in renal transplantation because of the activation of many infections mainly viruses. The study was designed to evaluate the frequency of Torque teno virus (TTV) viremia among renal transplant recipients (RTR). Objective: To detect TTV in a sample of Iraqi RTR, and its association with renal functions. Methods: This cross-sectional study included 80 serum samples collected from RTR and subjected for TTV detection by real-time polymerase chain reaction (RT-PCR). Results: Qualitative RT-PCR run gave positive results for TTV in 45 out of 80 (56.25%) RTR, the results showed non-significant association between TTV and allograft rejection (p=0.26). Conclusion: TTV seems not associated with post transplantation renal impairment and/or kidney rejection. Keywords: Torque teno virus, renal transplantation, RTR Citation: Taher NM, Hussein MR, Al-Obaidi AB, Kadhim HS. The possible role of Torque teno virus in kidney allograft recipients in a sample of Iraqi patients. Iraqi JMS. 2020; 18(2): 130-137. doi: 10.22578/IJMS.18.2.7