The postnatal growth of the vomeronasal organ of the albino rat (Mus norvegicus albinus)

Addison, William H. F.; Rademaker, Lee

doi:10.1002/cne.900440105

Cited by 25 publications

(16 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Wöhrmann-Repenning (1981) showed that the VNO of the rabbit does not connect to the nasopalatine duct, as in most mammals, but is directed to the oral cavity. In the mole rat too the VNO opens directly to the NC by a narrow canal, previously also described in other rodents, such as the laboratory rat (Rattus norvegicus) by Addison and Rademaker (1927), and in several species of bats and vampire bats (Mann, 1961). As in laboratory rats (Addison and Rademaker, 1927), in developing mole rats too there is a constant increase in the dimensions of the VNO, but its relative proportions to the NC decrease.…”

Section: Estimatedmentioning

confidence: 85%

“…In the mole rat too the VNO opens directly to the NC by a narrow canal, previously also described in other rodents, such as the laboratory rat (Rattus norvegicus) by Addison and Rademaker (1927), and in several species of bats and vampire bats (Mann, 1961). As in laboratory rats (Addison and Rademaker, 1927), in developing mole rats too there is a constant increase in the dimensions of the VNO, but its relative proportions to the NC decrease. At all ages in the mole rat, the connection between the VNO and the NC (canalis incisivum) is open, suggesting that it is functional in both juveniles and adults.…”

Section: Estimatedmentioning

confidence: 85%

“…As in other mammals (Addison and Rademaker, 1927;Bhatnagar and Wible, 1994;Halpern, 1987), the VNO of the blind mole rat comprises a pair of elongated organs situated at the ventral part of the nasal septum (Figs. 2, 3).…”

Section: The Vomeronasal Organmentioning

confidence: 99%

See 2 more Smart Citations

Morphology and cytology of the nasal cavity and vomeronasal organ in juvenile and adult blind mole rats (Spalax ehrenbergi)

1998

View full text Add to dashboard Cite

The blind mole rat (Spalax ehrenbergi) is a fossorial solitary rodent which exhibits extensive intraspecific aggression and uses scent markings to deter contraspecific invaders.Mole rats of different ages were captured near Tel Aviv, Israel, and sacrificed by an overdose of Xylazine hydrochloride. Olfactory epithelium sites from the nasal cavity (NC) and the vomeronasal organ (VNO) were dissected and fixed for light and electron microscopy.The mole rat's olfactory epithelium of the NC consists of several cell types, of which two types are supporting cells that comprise both microvilli and cilia but differ in staining and the presence of rough endoplasmic reticulum. The third type has no cilia. Secretory goblet cells were frequent among supporting cells of adults alone. Two types of receptor cells protrude into the NC with olfactory knobs at their apical region; one type has up to 177.6 Ϯ 9.4 cilia per knob plus microvilli, while the other type has only microvilli. The third type of sensory cell has no knob and contains microvilli only. The basal epithelium layer consists of short-bodied cells with round nuclei.The VNO of the mole rat is situated beneath the nasal septum, consisting of supporting, sensory, and basal cell types, with many cilia at the apical portion. At its anterior part, the VNO is connected to the NC by narrow canals.The abundance of cilia and microvilli in the mole rat olfactory cells provides the first anatomical evidence for their olfactory acuity. Such acuity is important in mole rats, compensating for their loss of vision and enabling them to detect and avoid rivals prior to potential aggressive encounters as well as to select food plants during foraging. Anat.

show abstract

Section: Estimatedmentioning

confidence: 85%

Section: Estimatedmentioning

confidence: 85%

See 1 more Smart Citation

Morphology and cytology of the nasal cavity and vomeronasal organ in juvenile and adult blind mole rats (Spalax ehrenbergi)

1998

View full text Add to dashboard Cite

show abstract

“…Their data suggest that even though the population of basal cells in the central portion of the VNSE is sparse, it could constitute a cell pool to replace apoptotic VRNs. Weilter et al (1999a) and Martínez-Marcos et al (2000a) suggest that dividing cells in the margins of the VNSE contribute to the continuous growth of the rat VNO (Addison and Rademaker, 1927;Weiler et al, 1999a;Wilson and Raisman, 1980). Experimental axotomy of the VNN (Barber and Raisman, 1978b;Ichikawa et al, 1998) and bulbextomy of the VNB (Martínez-Marcos et al, 2000a) in rodents resulted in degeneration and regeneration of VRNs.…”

Section: Differentiation and Turnover Of Vomeronasal Receptor Neuronsmentioning

confidence: 95%

Recent progress in the neurobiology of the vomeronasal organ

Takami

2002

Microscopy Res & Technique

View full text Add to dashboard Cite

In many terrestrial tetrapodes, a pair of vomeronasal organs (VNOs), which are chemosensory apparatuses, are situated at the base of the nasal septum in the anterior nasal cavity. The purposes of this review are to summarize comparative neuroanatomy and to introduce recent progress in neurobiological studies of the VNO. Five types of VNOs can be identifiable in terms of anatomical organization; snakes possess the most complex one. Sensory cells in the VNO, vomeronasal receptor neurons (VRNs), are located in its neuroepithelium, vomeronassal sensory epithelium. The VRNs retain the characteristic of epithelial cells in that they are born continuously from progenitor cells. They contain two prominent subcellular structures: microvilli and extraordinarily large amounts of smooth endoplasmic reticulum and a few unique glycoconjugates. The VRNs express two types of G-protein -subunits: Gi(alpha2) and Go(alpha) and each of them is coupled with putative pheromone receptors, V1Rs and V2Rs, respectively. Recent physiological and biochemical studies have demonstrated that pheromones depolarize the V1R-Gi(alpha2) and V2R-Go(alpha) VRNs via IP(3)-mediated mechanisms. The VRNs do not show adaptation and are ultrasensitive to putative pheromones. Other than being a chemosensory organ, the VNO and its primordium might play important roles for brain development; hypothalamic neurons that produce gonadotropin-releasing hormone are born in the VNO primordium and a few other neuron-like cells may be born in the VNO primordium and VNO. In human fetuses, anatomical findings strongly suggest that their VNOs contain a neuroepithelium. By contrast, it is unlikely that adult human VNO serves as a chemosensory organ.

show abstract

“…Such differences have been reported for both absolute and/or relative (e.g., to body size) measurements (but see , for a discussion on the appropriateness for scaling data on sensory organs). A few studies have documented age-related changes in VNO size of rodents (Addison and Rademaker, 1927;Weiler et al, 1999a;Wilson and Raisman, 1980). To date, no studies have investigated such data in non-human primates.…”

Section: Introductionmentioning

confidence: 99%

The vomeronasal organ of greater bushbabies (Otolemur spp.): Species, sex, and age differences

et al. 2005

View full text Add to dashboard Cite

The present study examined interspecies, intersexual, and age-related changes in size of the vomeronasal neuroepithelium (VNNE) of two species of greater bushbabies (genus Otolemur, Infraorder Lorisiformes, Suborder Strepsirrhini). Tissue blocks containing the vomeronasal organs of nine O. crassicaudatus (8 adults, 1 neonate) and ten O. garnettii (9 adults, 1 neonate) were studied by means of serial paraffin sectioning and computer-based reconstruction of VNNE volume. In addition, the immunoreactivity of the VNNE to two neuronal markers, neuron-specific beta tubulin (BT) and olfactory marker protein (OMP) was compared between species, sexes, and ages. Results indicated that a clear VNNE is present at birth in both species, and OMP immunoreactivity was verified in O. garnettii at birth. Male and female adults of both species showed OMP-immunoreactive and BT-immunoreactive neurons in the VNNE. Immunohistochemical findings indicated that all males and the youngest females had the thickest VNNE, especially at the marginal junctions with the receptor-free epithelium. Results of a 2-way Analysis of Variance (ANOVA, species x sex) revealed no significant differences in VNNE length or volume between species, but O. crassicaudatus had significantly ( p < 0.05) greater palatal length. Significant ( p < 0.05) differences also were found between sexes in VNNE volume, but no significant differences in palatal length or VNNE length. The distribution of VNNE volume against age indicated that the sex differences were more pronounced in O. crassicaudatus than O. garnettii. For both species and sexes, distribution of VNNE volume against age suggested an age-related reduction in volume. These findings demonstrate postnatal plasticity in VNNE size in Otolemur that is reminiscent of that found for olfactory structures in some rodents. Bushbabies or other strepsirrhine primates may offer an opportunity for further understanding of behavioral correlates of VNNE postnatal plasticity, which may represent primitive functional characteristics of the order Primates.Abbreviation: BT, beta tubulin; IHC, immunohistochemistry; OMP, olfactory marker protein; RFE, receptor-free epithelium; VNNE, vomeronasal neuroepithelium; VNO, vomeronasal organ; VRN, vomeronasal receptor neurons.

show abstract

The postnatal growth of the vomeronasal organ of the albino rat (Mus norvegicus albinus)

Cited by 25 publications

References 5 publications

Morphology and cytology of the nasal cavity and vomeronasal organ in juvenile and adult blind mole rats (Spalax ehrenbergi)

Morphology and cytology of the nasal cavity and vomeronasal organ in juvenile and adult blind mole rats (Spalax ehrenbergi)

Recent progress in the neurobiology of the vomeronasal organ

The vomeronasal organ of greater bushbabies (Otolemur spp.): Species, sex, and age differences

Contact Info

Product

Resources

About