The postoperative venous thromboembolism (TREVO) study – Risk and case mortality by surgical specialty

Amaral, Cristina; Pereira, Luís Guimarães; Moretó, Ana; Sá, Ana Carolina; Azevedo, Ana

doi:10.1016/j.repce.2016.11.016

Cited by 5 publications

(2 citation statements)

References 20 publications

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“…Both active malignancy and major surgical procedures are independent risk factors for the development of VTE. Previous studies have found that postoperative thromboembolic complications span all surgical specialties, 3 with high rates following major musculoskeletal surgery 4–7 . This increases morbidity and mortality for patients undergoing these types of procedures 8 .…”

Section: Introductionmentioning

confidence: 99%

Venous thromboembolism rates in patients with bone and soft tissue sarcoma of the extremities following surgical resection: A systematic review

Krzyzaniak

You

Mosca

et al. 2021

Journal of Surgical Oncology

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Background: Patients undergoing an orthopedic surgery for bone or soft tissue sarcoma are at increased venous thromboembolism (VTE) risk. Unfortunately, there is a lack of thromboprophylaxis guidelines in this population. The purpose of this systematic review was to determine the soft tissue and bone sarcoma VTE rate and to explore the thromboprophylaxis regimens used.Methods: The databases MEDLINE, EMBASE, and CENTRAL were queried using keywords related to VTE and long bone malignancy requiring surgical intervention to 2020. Included studied reported VTE rate in patients with surgically managed extremity sarcoma. Descriptive statistics and weighted mean totals were calculated.Results: A total of 2082 studies were screened and 23 studies were included. The overall VTE rate was 2.9%, with a rate of 3.7% and 1.4% in patients with bone and soft tissue sarcomas, respectively. Low-molecular-weight heparin was the most commonly used chemoprophylaxis.Conclusions: There is a high VTE rate following sarcoma surgery. The VTE rate is higher in bone sarcoma surgery, which may be attributed to differences in surgery and postoperative recovery. There was no consensus on the duration or type of thromboprophylaxis used. Future research is needed to determine the most effective thromboprophylaxis regimen in patients with sarcoma and whether individualized thromboprophylaxis is required.

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Section: Introductionmentioning

confidence: 99%

Venous thromboembolism rates in patients with bone and soft tissue sarcoma of the extremities following surgical resection: A systematic review

Krzyzaniak

You

Mosca

et al. 2021

Journal of Surgical Oncology

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“…Studies have shown that among hospitalized patients, neurosurgical patients have one of the highest risks of VTE, belonging to the high-risk group of VTE [6]. The American Society of Hematology 2019 guidelines for the management of VTE also noted that patients undergoing invasive neurosurgery had the highest risk of VTE among all surgical patients [7].…”

Section: Introductionmentioning

confidence: 99%

Low awareness of venous thromboembolism (VTE) among neurosurgical hospitalized patients: a cross-sectional study

Pan

Wiley

Tian

et al. 2022

Preprint

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Background: Venous thromboembolism (VTE) including Deep Venous Thrombosis (DVT) and Pulmonary Embolism (PE), is a serious cause of patient morbidity and mortality in hospitals. Neurosurgical hospitalized patients have higher rates of immobility and bed rest, thus increasing their risk of developing VTE. This highlights the need for their thromboprophylaxis regimens. Patients'awareness of VTE is essential for promoting strategies such as early ambulation and encouraging self-assessment and self-reporting of VTE signs and symptoms. This study evaluated neurosurgical hospitalized patients’ awareness of VTE and explored the influencing factors to provide a theoretical basis for nursing intervention. Methods: We selected one tertiary level hospital in Hunan Province and randomly sampled eligible patients from each five neurosurgical units. We conducted a cross-sectional survey of the hospitalized patients of neurosurgery using the VTE knowledge questionnaire, and the influencing factors were analyzed using SPSS 26.0. Results: A total of 386 neurosurgical hospitalized patients completed the survey. The score of VTE knowledge in neurosurgical hospitalized patients was 13.22 (SD=11.52). 36.0% and 21.2% of participants reported they had heard of DVT and PE, respectively. 38.9% of participants were unable to correctly identify any symptoms of VTE. The most frequently identified risk factor was ‘immobility or bed rest for more than three days’ (50.0% of participants), and 38.1% of patients agreed that PE could cause death. 29.5% of participants were unable to identify any prophylactic measures of VTE. The results of Negative Binomial Regression showed that the influencing factors of VTE knowledge in neurosurgical hospitalized patients were education level (P<0.004) and sources of information related to VTE, including nurses (95% CI=2.201-4.374, P<0.001), and family member/friend (95% CI=2.038-4.331, P<0.001), Internet/TV (95% CI=1.382-2.834, P＜0.001). Other sources included patient /pamphlet/poster /professional books (95% CI=492-3.350, P<0.001). Conclusions: This study demonstrates the lack of awareness of VTE among neurosurgical hospitalized patients. More attention must be paid to carrying out training on VTE knowledge according to different characteristics of neurosurgical hospitalized patients, so as to ensure safe and high-quality patient care.

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What is the value of preoperative prophylactic heparin in reducing venous thromboembolism in major non-cardiac thoracic surgery?

Odewade¹,

Enofe²,

Soni³

et al. 2022

The American Journal of Surgery

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The postoperative venous thromboembolism (TREVO) study – Risk and case mortality by surgical specialty

Cited by 5 publications

References 20 publications

Venous thromboembolism rates in patients with bone and soft tissue sarcoma of the extremities following surgical resection: A systematic review

Venous thromboembolism rates in patients with bone and soft tissue sarcoma of the extremities following surgical resection: A systematic review

Low awareness of venous thromboembolism (VTE) among neurosurgical hospitalized patients: a cross-sectional study

What is the value of preoperative prophylactic heparin in reducing venous thromboembolism in major non-cardiac thoracic surgery?

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