The potential for zoonotic malaria transmission in five areas of Indonesia inhabited by non-human primates

Permana, Dendi Hadi; Hasmiwati,; Suryandari, Dwi Anita; Rozi, Ismail Ekoprayitno; Syahrani, Lepa; Setiadi, Wuryantari; Irawati, Nuzulia; Rizaldi,; Wangsamuda, Suradi; Yusuf, Yenni; Irdayanti,; Aswad, Hijral; Asih, Puji Budi Setia; Syafruddin, Din

doi:10.1186/s13071-023-05880-4

Cited by 1 publication

(1 citation statement)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…More specifically, Plasmodium cynomolgi and Plasmodium inui were detected in the largest number of host primate species, including Macaca fascicularis , M. nemestrina , M. leonina , M. arctoides , M. sinica (only for P. cynomolgi ), M. radiata , and Presbytis entellus (only for P. cynomolgi ) ( 53–66 ). In addition, Plasmodium falciparum was detected in M. radiata and M. mulatta ( 56 ), while P. knowlesi was detected in M. fascicularis , M. nemestrina , and M. arctoides ( 53 , 54 , 57 , 59–61 , 64–69 ). These two zoonotic Plasmodium species are known to cause severe cases of malaria in humans.…”

Section: Resultsmentioning

confidence: 99%

Zoonotic pathogens in wild Asian primates: a systematic review highlighting research gaps

Patouillat,

Hambuckers,

Adi Subrata

et al. 2024

Front. Vet. Sci.

View full text Add to dashboard Cite

IntroductionOngoing global changes, including natural land conversion for agriculture and urbanization, modify the dynamics of human–primate contacts, resulting in increased zoonotic risks. Although Asia shelters high primate diversity and experiences rapid expansion of human–primate contact zones, there remains little documentation regarding zoonotic surveillance in the primates of this region.MethodsUsing the PRISMA guidelines, we conducted a systematic review to compile an inventory of zoonotic pathogens detected in wild Asian primates, while highlighting the coverage of primate species, countries, and pathogen groups surveyed, as well as the diagnostic methods used across the studies. Moreover, we compared the species richness of pathogens harbored by primates across diverse types of habitats classified according to their degree of anthropization (i.e., urban vs. rural vs. forest habitats).Results and discussionSearches of Scopus, PubMed, and the Global Mammal Parasite Database yielded 152 articles on 39 primate species. We inventoried 183 pathogens, including 63 helminthic gastrointestinal parasites, two blood-borne parasites, 42 protozoa, 45 viruses, 30 bacteria, and one fungus. Considering each study as a sample, species accumulation curves revealed no significant differences in specific richness between habitat types for any of the pathogen groups analyzed. This is likely due to the insufficient sampling effort (i.e., a limited number of studies), which prevents drawing conclusive findings. This systematic review identified several publication biases, particularly the uneven representation of host species and pathogen groups studied, as well as a lack of use of generic diagnostic methods. Addressing these gaps necessitates a multidisciplinary strategy framed in a One Health approach, which may facilitate a broader inventory of pathogens and ultimately limit the risk of cross-species transmission at the human–primate interface. Strengthening the zoonotic surveillance in primates of this region could be realized notably through the application of more comprehensive diagnostic techniques such as broad-spectrum analyses without a priori selection.

show abstract