The potential impact of climate change and ultraviolet radiation on vaccine-preventable infectious diseases and immunization service delivery system

Guo, Biao; Naish, Suchithra; Tong, Shilu

doi:10.1586/14760584.2014.990387

Cited by 11 publications

(7 citation statements)

References 85 publications

(158 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A study in Hong Kong found solar radiation was positively associated with all respiratory disease hospitalizations [ 39 ]. Some vaccine-preventable infectious diseases, including Japanese encephalitis, yellow fever, influenza, rotavirus infection, hepatitis A virus infection and hepatitis B virus infection, were also found to be differentially influenced by ultraviolet radiation from the sun through modulating vector reproduction [ 40 ]. In addition, a preventive effect of indoor solar radiation on HFMD was presumed [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Hand, Foot and Mouth Disease in Hong Kong: A Time-Series Analysis on Its Relationship with Weather

2016

View full text Add to dashboard Cite

BackgroundHand, foot and mouth disease (HFMD) is an emerging enterovirus-induced infectious disease for which the environmental risk factors promoting disease circulation remain inconclusive. This study aims to quantify the association of daily weather variation with hospitalizations for HFMD in Hong Kong, a subtropical city in China.MethodsA time series of daily counts of HFMD public hospital admissions from 2008 through 2011 in Hong Kong was regressed on daily mean temperature, relative humidity, wind speed, solar radiation and total rainfall, using a combination of negative binomial generalized additive models and distributed lag non-linear models, adjusting for trend, season, and day of week.ResultsThere was a positive association between temperature and HFMD, with increasing trends from 8 to 20°C and above 25°C with a plateau in between. A hockey-stick relationship of relative humidity with HFMD was found, with markedly increasing risks over 80%. Moderate rainfall and stronger wind and solar radiation were also found to be associated with more admissions.ConclusionsThe present study provides quantitative evidence that short-term meteorological variations could be used as early indicators for potential HFMD outbreaks. Climate change is likely to lead to a substantial increase in severe HFMD cases in this subtropical city in the absence of further interventions.

show abstract

Section: Discussionmentioning

confidence: 99%

Hand, Foot and Mouth Disease in Hong Kong: A Time-Series Analysis on Its Relationship with Weather

2016

View full text Add to dashboard Cite

show abstract

“…Experimental studies indicate that UVR-induced immune suppression is both local and systemic and may affect delayed type hypersensitivity reactions. Exposure to SR may reactivate latent viral infections (e.g., herpes simplex virus) and epidemiological studies suggest that SR exposure may impair to some extent the effectiveness of vaccines [72][73][74]. As shown in Figure 1, several potential implications of SR-induced immune suppression (some of them involving a net beneficial effect while others result in adverse outcomes) are not yet clearly highlighted by experimental and epidemiological studies.…”

Section: Immune Effectsmentioning

confidence: 99%

Balance between Health Risks and Benefits for Outdoor Workers Exposed to Solar Radiation: An Overview on the Role of Near Infrared Radiation Alone and in Combination with Other Solar Spectral Bands

Grandi

D’Ovidio

2020

IJERPH

View full text Add to dashboard Cite

Near infrared or infrared A (IRA) accounts for over 40% of the solar spectrum (SS) and is able to reach subcutaneous tissue as well as the retina. Outdoor workers are occupationally exposed to solar radiation (SR), but the level of exposure may differ widely depending on the job performed, time spent outdoors, latitude, altitude, season, personal protection, etc. Until now, risk assessment and management for outdoor workers has focused on the prevention of both acute and long-term effects on the eye and the skin due to solar ultraviolet radiation (UVR) with little consideration of the other components of the SS (a possible exception is represented by visible radiation with reference to the eye). A growing body of evidence coming from in vitro studies indicates that IRA is involved in cellular reactive oxygen species (ROS) production and may interfere with the respiratory chain in the mitochondria. Moreover, it can modulate gene expression and some metabolic pathways. The biological action of IRA is only partly attributable to a thermal mechanism, should it be also involved in photochemical ones. The cellular and molecular pathways affected by IRA are partly similar and partly different with respect to those involved in the case of visible ultraviolet A (UVA) and ultraviolet B (UVB) radiation. Consequently, the net effect of the SS is very difficult to predict at different levels of the biological organization, making more difficult the final balance of health risk and benefits (for the skin, eye, immune system, blood pressure, etc.) in a given exposure situation. Moreover, few in vivo studies and no epidemiological data are presently available in this regard. Investigating this topic may contribute to better defining the individual exposome. More practically, it is expected to bring benefits to the risk assessment and management for outdoor workers exposed to SS, contributing to: (1) better definition of the individual profiles of susceptibility, (2) more focused preventive and protective measures, (3) better implementation of the health surveillance and (4) a more effective information and training.

show abstract

“…Sunlight may increase temperatures at the ground level, particularly in concrete‐dominated urban settings, contributing to viral spread . Moreover, certain vaccine‐preventable infections have been found to be differentially influenced by ultraviolet radiation via modulation of vector reproduction, suggesting that sunlight may play a role in disease transmissibility . In theory, stronger winds may facilitate the spread of respiratory droplets up to a certain threshold, after which extreme wind speeds may hinder attachment to materials in the environment …”

Section: Discussionmentioning

confidence: 99%

Temperature and humidity affect the incidence of hand, foot, and mouth disease: a systematic review of the literature – a report from the International Society of Dermatology Climate Change Committee

2018

View full text Add to dashboard Cite

Hand, foot, and mouth disease (HFMD) is an enterovirus-mediated condition that predominantly affects children under 5 years of age. The tendency for outbreaks to peak in warmer summer months suggests a relationship between HFMD and weather patterns. We reviewed the English-language literature for articles describing a relationship between meteorological variables and HFMD. Seventy-two studies meeting criteria were identified. A positive, statistically significant relationship was identified between HFMD cases and both temperature (61 of 67 studies, or 91.0%, reported a positive relationship) [CI 81.8-95.8%, P = 0.0001] and relative humidity (41 of 54 studies, or 75.9%) [CI 63.1-85.4%, P = 0.0001]. No significant relationship was identified between HFMD and precipitation, wind speed, and/or sunshine. Most countries reported a single peak of disease each year (most commonly early Summer), but subtropical and tropical climate zones were significantly more likely to experience a bimodal distribution of cases throughout the year (two peaks a year; most commonly late spring/early summer, with a smaller peak in autumn). The rising global incidence of HFMD, particularly in Pacific Asia, may be related to climate change. Weather forecasting might be used effectively in the future to indicate the risk of HFMD outbreaks and the need for targeted public health interventions.

show abstract

The potential impact of climate change and ultraviolet radiation on vaccine-preventable infectious diseases and immunization service delivery system

Cited by 11 publications

References 85 publications

Hand, Foot and Mouth Disease in Hong Kong: A Time-Series Analysis on Its Relationship with Weather

Hand, Foot and Mouth Disease in Hong Kong: A Time-Series Analysis on Its Relationship with Weather

Balance between Health Risks and Benefits for Outdoor Workers Exposed to Solar Radiation: An Overview on the Role of Near Infrared Radiation Alone and in Combination with Other Solar Spectral Bands

Temperature and humidity affect the incidence of hand, foot, and mouth disease: a systematic review of the literature – a report from the International Society of Dermatology Climate Change Committee

Contact Info

Product

Resources

About