The potential of Moringa oleifera as immune booster against COVID 19

Abstract

COVID-19 is a new disease that has become a pandemic. This disease should be watched out for because transmission is relatively fast, has a mortality rate that cannot be ignored, and there is no definitive therapy. After COVID 19, people will be more selective in the food they eat. The types of food chosen were those that have health benefits, especially as immunity boosters. The problem was what types of products can provide these benefits en masse, cheap, and easy to access. This review aims to explore the potential of the Moringa plant as a plant that can be a source of functional food as a post-COVID 19 immune booster. The method used was to review various journal references that discuss research results related to the use of Moringa plants and specifically those related to the anticipation of COVID 19. Based on the results of a review of various literature, it was found that the Moringa plant has various functional properties. These health functions include, among others, anti-inflammatory, antimicrobial, antidiabetic, antioxidant, anti-tumor, anticancer, antihypertensive, antiasthmatic, antiurolithiasis, anthelmintic, anti-fertility, antihyperthyroid, and anti-Alzheimer. One of the roles of Moringa plants in dealing with COVID 19 was as an immune booster. This is important because one of the factors that cause the different severity of COVID 19 patients is immunity. People with good body immunity tend to be able to survive infection and attacks by the SARS-Cov-2. Some of the components of Moringa that play a role in this were kaempferol, pterygospermin, morphine, quercetin, and apigenin-7-O-rutinoside. Apigenin has the highest activity against SARS-Cov-2-MPro (the main protease of COVID 19). From the results of this review, it can be concluded that the Moringa plant has the potential as an immune booster against the SARS-Cov-2 (COVID 19).

A comprehensive review of the phytochemicals, health benefits, pharmacological safety and medicinal prospects of Moringa oleifera

“…Unfortunately, till now March 2022, no effective and standard treatment has been found [ 37 ]. Due to the high infectivity and mortality rate of this disease, caused by the virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), together with its resistance to various drugs and high mutation rate, the urgency for a therapeutic agent to combat this virus has surged [ 37 , 38 ]. Several plants have been used in Chinese and Ayurvedic medicine for centuries due to their anti-viral and anti-microbial properties.…”

Moringa oleifera: Review on herbal healing properties and Nutritional values

“…Some of the Moringa oleifera constituents that function include kaempferol, pterygospermin, morphine, quercetin, and apigenin. The most effective anti-SARS agent against MPro-Cov-2 is apigenin [112] . In contrast to the well-known SARS-CoV-2 MPro inhibitor baicalein, three flavonoids-isorhamnetin, kaempferol, and apigenin demonstrated good binding empathy stable protein-ligand complexes with high binding energy and similar binding poses [113] .…”

An Ethnographic Study of the Concept of COVID-19 in the Belu Community Beliefs

“…Moringa trees can be used to prevent many pathogenic infections including SARS-CoV (Bhattacharjee, 2020;Fajri, 2021). Furthermore, based to Meireles et al, (2020) the Moringa leaf (Moringa oleifera) is the most frequently used part and can overcome severe nutritional deficiencies, remove moisture and heat and remove toxins.…”