The potential of nutritional supplements: methyl donor rich food and their application in oncology

Abstract

Nowadays, a wide range of diets and dietary supplements are available for oncology patients. As far as these products are concerned, mostly the beneficial effects of them are promoted, but unfortunately, it is difficult to obtain valuable information about the actual effects or potential dangers of these supplements, as these are not drugs, so different quality requirements stated against compared to pharmaceuticals. This in itself raises profound concerns about the potential harm of using such products, as in many cases it is impossible to exactly know the content, and pollutants that can be found in these supplements. During oncological treatment, patients often go for additional supplements in the hope of healing. In most of the cases, this bears no harm, but there is minuscul evidence of their positive effects. The aim of this study was to review the most frequently used methyl-donors in oncological care, to present their chemical background, and give practical examples based on available evidences.