The Potential of Palladacycles:  More Than Just Precatalysts

Rational Perturbation of the Fluorescence Quantum Yield in Emission‐Tunable and Predictable Fluorophores (Seoul‐Fluors) by a Facile Synthetic Method Involving CH Activation

“…Metal‐catalyzed C—H activation methods are powerful, straightforward, and atom‐economical synthetic tools for carbon–carbon and carbon–heteroatom bond formation 7a,b. Palladium(II)‐catalyzed C—H activation has emerged as an important catalytic transformation because of its versatility for the installation of many different types of bonds and its exceptional practicality under ambient conditions in the presence of moisture 7c,d.…”

Platinum(II) and palladium(II) complexes with (N,N′) and (C,N,N′)− ligands derived from pyrazole as anticancer and antimalarial agents: Synthesis, characterization and in vitro activities

“…Cyclometallated complexes derived from N-donor ligands have attracted great interest during the last decade due to their properties and applications in a wide variety of fields [10,[20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] and compounds of this kind containing Pd(II), Pt(II), Ru(II), Ir(III) Rh(III) and Au have shown promising cytotoxic activities [10,20,[27][28][29][30][31][32][33][34][35][36]. Few cyclopalladated complexes derived from pyrazole are known [37][38][39][40][41] and, to the best of our knowledge, their cytotoxicity has only been reported once [41].…”

Novel palladium complexes for catalysis and biomedical applications

“…To overcome their high lability, chelating ligands have been used to afford high thermodynamically stable and kinetically inert Pd(II) complexes. In particular, palladacycles are nowadays attracting attention as potential anticancer agents [7,8]. The present work reports on x-ray structure of six novel Pd(II) complexes, of which three are cyclopalladates showing antitumor activity comparable to that of cis-platinum, the other three being the substrates for synthesis of cyclometallated products.…”