The potential population‐based impact of an HPV vaccination intervention in Colorado

Abstract

Background Human papillomavirus (HPV) infection is the most common cause of cervical cancer and can be prevented with vaccination, but HPV vaccination rates remain low. An intervention to improve health care provider communication about vaccination has been shown to increase HPV vaccination rates in an initial trial in Colorado, where about 160 cases of cervical cancer are diagnosed each year. Methods Census data were combined with Colorado cancer and immunization registry data to identify clinics in locations that would most benefit from implementation of this intervention to improve HPV vaccination rates. ArcGIS Pro was used to map cervical cancer incidence, immunization rates, population data, and location of clinics participating in practice‐based research networks (PBRNs). Results from the provider communication intervention trial and published estimates of the number needed to vaccinate to prevent a case of cervical cancer were used to predict the number of cervical cancer cases prevented based on increased vaccination due to the intervention. Results Ninety‐eight Colorado PBRN clinics were analyzed. For the 10 clinics with the highest predicted number of cervical cancer cases prevented, 5218 additional patients would be vaccinated and 43 cervical cancer cases prevented with implementation of the intervention. If implemented in all 98 clinics, the intervention would lead to 20 490 additional patients vaccinated (range 7‐658/clinic) and 171 cases of cervical cancer prevented (range 0.05‐5.48/clinic). Conclusions Geographic data from cancer and immunization registries can inform the dissemination of evidence‐based practices like the provider communication intervention for HPV vaccination to maximize impact on public health.

Adult vaccination coverage in the United States: A database analysis and literature review of improvement strategies

“…Eight articles reported on interventions involving patient or provider education ( Table 2 ). 17 , 20 , 25 , 26 , 32 , 35 , 39 , 47 A majority reported improved vaccination rates following the intervention, 20 , 26 , 32 , 35 , 39 and those that did not observe increased vaccination rates reported higher participant readiness to receive vaccination. 17 , 25 To improve vaccination rates in a community pharmacy setting, Brackett et al 17 assessed the use of motivational interviewing–based interventions ( n = 19 motivational interview encounters), in which two pharmacists conducted collaborative, person-centered interviews with eligible patients to elicit intrinsic motivation to receive vaccination.…”

“…Lastly, a communication aids and training intervention in a modeling study by Cataldi et al 20 ( n = 98 clinics) led to an estimated additional 5,218 vaccinated patients and 43 cervical cancer cases prevented among the 10 clinics with the highest predicted number of cervical cancer cases prevented. However, the predicted number of cases of cervical cancer prevented by the intervention may be underestimated in this study due to time horizon differences and the analysis not accounting for people aging in (or out) of the age range of eligibility for routine HPV vaccination.…”