The Potential Risk Factors and the Identification of Hearing Loss in Infants

Biswas, Avik; Goswami, S. C.; Baruah, D. K.; Tripathy, Rajesh

doi:10.1007/s12070-011-0307-6

Cited by 16 publications

(8 citation statements)

References 7 publications

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“…This finding was similar to another study done in Gauhati Medical College Hospital, India. [18] Similar to another study by Pisani F et al [15] this study also showed association of multiple episodes of seizure with poor neurologic outcome including vision and hearing loss.…”

Section: Discussionsupporting

confidence: 84%

Etiological Profile and Neurodevelopment Outcome of Neonatal seizure

Singh

Shrestha

2018

J Lumbini Med Coll

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IntroductionNeonatal seizures are the most common manifestation of neurological disorders in newborn period. It is an important determinant of outcome as well. This study aims to delineate the etiological profile and neurodevelopmental outcome of neonatal seizure. It is also aimed to identify the predictors of neurodevelopmental outcome in survivors. MethodsWe recruited consecutively 117 neonates with clinically proven seizures admitted in XXXXX hospital, between February 2014 to February 2016. All of them underwent neurological diagnostic testincluding complete blood count, electrolytes, EEG, CSF analysis, neuroimaging depending upon the etiology of seizure in newborn period. After discharge, all infant with neonatal seizure underwent regular neurological examination at least 3 times within first year of life. We tested prognostic value of adverse outcome including developmental delay, post neonatal seizure, vision and hearing impairment.ResultsDuring the study period among total 954 neonates admitted in NICU and neonatal ward, 117 (12.26%) developed clinical seizures. The most common cause of neonatal seizure was hypoxic ischemic encephalopathy 69(59%), followed by infection 20 (17.09%) and metabolic disturbances collectively constituted 16(13.7%). The outcomes were mortality 16(13.7%), post neonatal seizure 18(15.4%), developmental delay 31(26.5%), vision impairment 19(16.2%) and hearing impairment 26 (22.2%).Low Apgar score at 1 minute (p=0.03), low Apgar score at 5 minute (p=0.001), early onset seizure (p<0.001), intractable seizure (p<0.001)and more than one drug used for seizure control (p=0.001) were early prognostic factors for adverse outcome.Key words: hypoxic ischemic encephalopathy, Apgar score, seizure, developmental delay

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Section: Discussionsupporting

confidence: 84%

Etiological Profile and Neurodevelopment Outcome of Neonatal seizure

Singh

Shrestha

2018

J Lumbini Med Coll

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“…In our study, ototoxic medication was the most frequent risk factor, followed by hyperbilirubinaemia, prematurity, mechanical ventilation, low birth-weight, and post-genital infections. These factors were the most frequently observed in high risk infants for HL; also in other trials with predominance of low birth-weight, prematurity, and ototoxic drug administration [17][18][19]. However, the frequent existence of a specific risk factor does not necessarily mean that this factor has any causative effect to the outcomes of screening.…”

Section: Risk Factor *Nh(%) [N=163] **Ansd (%) [N=7] ***Hl (%) [N=3] Pmentioning

confidence: 90%

Neonatal Hearing Screening in Intensive Care Units

et al. 2014

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Background: Diagnosis of neonatal hearing impairment depends on universal hearing screening programs (otoacoustic emissions, OAEs, and/or auditory brainstem responses, ABRs). The aim of this study is to determine the prevalence of hearing impairment among high-risk newborns and identify the risk factors involved. Materials and methods:This is a prospective cohort study on 173 newborns hospitalized in a neonatal intensive care unit (NICU) with one or more risk factors for hearing impairment. Both TEOAEs and a-ABRs were performed a few days before discharge.Results: On examination with TEOAEs, 170 neonates eventually passed the test and 3 failed (1 bilaterally and 2 unilaterally). All neonates were also examined with a-ABR, and 10 failed the test, 7 of which passed TEOAE and were diagnosed as having possible auditory neuropathy spectrum disease (ANSD). The remaining 3 infants who failed both tests were diagnosed as having possible hearing loss (HL). From the risk factors, only TORCH infections were clearly related to the likelihood of hearing impairment, either ANSD or HL (p=0.004). The need for mechanical ventilation was also significantly higher in newborns with possible HL, compared to those with normal results (66.7% vs. 18.4%, p=0.03). Conclusions:Combined TEOAE/ABR is the gold standard examination for NICU infants due to the increased incidence of HL, especially ANSD, in this high-risk population.

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“…11 Infections that can cause hearing disorders such as bacterial meningitis, intrauterine infections (CMV, rubella, herpes, syphilis, and toxoplasmosis). 14 The least health risk factors during the prenatal period were hypertension [2 patients (6.7%)] and medications used [2 patients (6.7%)]; in natal period was premature [3 patients, (10%)] and baby born without crying [3 patients, (10%)]. History of the use of herbs or medicines was also reported in Palembang although the type of herbs or medicines taken by patients are not cleared.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of Down Syndrome Children with Delayed Speech and Hearing Loss in Audiology Clinic, Dr. Soetomo Surabaya Hospital

2020

IJPHRD

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Background: Down syndrome is a pathologyrelated to trisomy 21 chromosome. The incidence of Down syndrome is approximately 1/1000 births in some countries. The syndrome is commonly associated with the risks of developmental delays, difficulties in speech and hearing loss.Objectives: To determine the prevalence and characteristics ofchildren with Down syndrome suffered from delayed speech and hearing loss in Audiology Clinic, Dr. Soetomo Hospital, Surabaya from January 2013-December 2017.Method: This study is an observational analysis with cross-sectional retrospective design onthe patient's medical record.Results: Thirty patients were diagnosed with delayed speech amongst the Down syndrome children; 19 (63.3%) were males; 11(36.7%) were females. The most frequent was in the age group of >1-2 years[8 patients (26.7%)]; the least was in the age group of 4-6 months [1 patient (3.3%)]. Hearing loss was found in 21 patients (70%) and the rest had normal hearing [9 patients, (30%)]. Amongst the first group, 1 patient (3.3%) had profound hearing loss, 8 patients (26.7%) had severe hearing loss, 11 patients (36.7%) had moderate hearing loss and 1 patient (3.3%) had mild hearing loss. Two patients (6.7%) had prenatal problem, 2 patients (6.7%) had natal problem, 7 patients (23.3%) had post-natal problem. Amongst these, 1 patient (3,3%) had prenatal and natal problems, 5 patients (16,7%) had natal and post-natal problems, 1 patient (3,3%) had prenatal and post-natal problems, 3 patients (10%) had prenatal, natal and post-natal problems, and the rests had no recorded problems. Conclusion:Hearing loss was prevalent in Down Syndrome children with delayed speech. This might be correlated to the prenatal, natal, post-natal health risk problems. The hearing loss should be considered during treatment of speech delay in Down Syndrome children.

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The Potential Risk Factors and the Identification of Hearing Loss in Infants

Cited by 16 publications

References 7 publications

Etiological Profile and Neurodevelopment Outcome of Neonatal seizure

Etiological Profile and Neurodevelopment Outcome of Neonatal seizure

Neonatal Hearing Screening in Intensive Care Units

Characteristics of Down Syndrome Children with Delayed Speech and Hearing Loss in Audiology Clinic, Dr. Soetomo Surabaya Hospital

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