The Potential Role of Regional Anesthesia in Perioperative Anti-Inflammatory Treatments

Faiz, Seyyed Hamid-Reza; Mohseni, Masood

doi:10.5812/aapm.5067

Cited by 4 publications

(1 citation statement)

References 19 publications

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“…Peripheral nerve blocks enjoy great importance in anaesthesia practice. They can provide safe and effective anaesthesia with long-lasting analgesia ( 1 , 2 ). Brachial plexus block is a widely employed regional nerve block of the upper extremity.…”

Section: Introductionmentioning

confidence: 99%

Unusually Prolonged Motor and Sensory Block Following Single Injection Ultrasound-Guided Infraclavicular Block With Bupivacaine and Dexamethasone

et al. 2013

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We present a case of unexpectedly prolonged motor and sensory block following a successful single injection ultrasound – guided infraclavicular block with bupivacaine (0.25%) and dexamethasone (8 mg). ultrasound guidance and safety measurement such as injection of the local anaesthetic at a slow rate and verifying that usual resistance was felt throughout the injection, has been applied. It took 42 hours for the block to go away. Although there was no evidence of neurologic injury but we should always be prepared to consider the possibility of nerve injury and take appropriate measures.

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Section: Introductionmentioning

confidence: 99%

Unusually Prolonged Motor and Sensory Block Following Single Injection Ultrasound-Guided Infraclavicular Block With Bupivacaine and Dexamethasone

et al. 2013

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Prolonged Interscalene Blockade for 30 Hours with 0.5% Plain Bupivacaine in a Case of Shoulder Arthroscopy

Tiwari¹,

Avhad²,

Mathkar³

et al. 2019

Turk J Anaesthesiol Reanim

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We present a case of unusually prolonged motor and sensory block for 30 hours after a successful single injection of ultrasound-guided interscalene block with 0.5% plain bupivacaine. All safety measures such as negative aspiration of blood injection at every 3 mL of drug with usual resistance, slow rate of injection and ultrasound documentation of spread of drug around C 5 and C 6 were followed. There was no evidence of neurological injury, but we should always be prepared to consider the possibility of nerve injury and take appropriate measures to prevent them.

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The Analgesic Efficacy of Intrathecal Bupivacaine and Fentanyl with Added Neostigmine or Magnesium Sulphate

Dori

Foruzin

2016

Anesth Pain Med

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BackgroundAn appropriate anesthesia duration with minimal side effects and prolonged postoperative analgesia are the ideal characteristics of an intrathecal drug used during spinal anesthesia. Neostigmine and magnesium sulphate have been used as spinal anesthetic additives with narcotics and local anesthetics.ObjectivesThis study aimed to assess the analgesic properties of intrathecal neostigmine and magnesium sulphate by adding them to intrathecal bupivacaine-fentanyl.Methods: In total, 210 patients undergoing tibial fracture surgery were enrolled in a double-blinded clinical trial study. Patients were randomly allocated to one of three groups: group F received 10 mg of bupivacaine and 25 µg of fentanyl as intrathecal drug for spinal anesthesia, group N received 150 µg of neostigmine added to 10 mg of bupivacaine and 25 µg of fentanyl, and group M received 50 mg of magnesium sulphate added to 10 mg of bupivacaine and 25 µg of fentanyl. Analgesia duration, motor blockade scores, postoperative pain scores 6 and 12 hours after surgery, postoperative voiding time, and the incidence of hypotension, bradycardia, respiratory depression, and nausea and vomiting were recorded.ResultsGroup M showed significantly longer analgesia duration (330.76 ± 80.98 minutes) than group F (280.98 ± 60.33 minutes). The pain scores in group M 6 hours (NRS: 2.44 ± 0.98) and 12 hours (NRS: 4.10 ± 0.88) after surgery were significantly lower than those of the other two groups. Before discharge from recovery, motor blockade scores and voiding time were not significantly different between the three groups. Hypotension (40%), bradycardia (25%), and nausea and vomiting (70%) were more obvious among group N patients. Respiratory depression did not occur in any patients.ConclusionsThe addition of 50 mg of magnesium sulfate to a bupivacaine–fentanyl solution for intrathecal anesthesia improved the efficacy and duration of the analgesia without any significant side effects. The addition of 150 µg of neostigmine increased the incidence of hypotension, bradycardia, and nausea and vomiting. Moreover, neostigmine failed to prolong analgesia duration.

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The Potential Role of Regional Anesthesia in Perioperative Anti-Inflammatory Treatments

Cited by 4 publications

References 19 publications

Unusually Prolonged Motor and Sensory Block Following Single Injection Ultrasound-Guided Infraclavicular Block With Bupivacaine and Dexamethasone

Unusually Prolonged Motor and Sensory Block Following Single Injection Ultrasound-Guided Infraclavicular Block With Bupivacaine and Dexamethasone

Prolonged Interscalene Blockade for 30 Hours with 0.5% Plain Bupivacaine in a Case of Shoulder Arthroscopy

The Analgesic Efficacy of Intrathecal Bupivacaine and Fentanyl with Added Neostigmine or Magnesium Sulphate

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