The current study aims to identify the role of the mediator for strategic persuasion in the relationship between altruistic leadership and the high performance of workers in Najaf Al-Ashraf Teaching Hospital (German) through applied knowledge frameworks on which the study relied. In achieving the high performance of workers through strategic persuasion, to address the problem of the study, a set of main and sub-hypotheses were formulated that are appropriate to the problem of the study and its objectives, considering altruistic leadership as an independent variable and the high performance of workers as a dependent variable, while strategic persuasion is considered a “mediator” variable, and through it a hypothetical scheme was designed that illustrates The nature of the effectual relationship between the variables of the study, Najaf Al-Ashraf Teaching Hospital (German) was chosen as a field community to analyze the scientific aspect of the study and rely on a sample of employees in the hospital. It was analyzed by (SmartPLS SPSS) program, and in the light of the results, the study reached a set of conclusions, the most important of which is that altruistic leadership has a direct impact on the high performance of the workers in the aforementioned hospital, but below the desired level, so the hospital should pay more attention to it. The study also proved that the mediating variable ( Strategic persuasion) contributed to raising the percentage of influence relationship between the independent variable (altruistic leadership) and the dependent variable (high performance of employees) in part. The management of the organization must clarify these aspects through training programs and seminars and meet with them periodically and continuously and urge them to this type of behavior.