“…The Van Den Berghe study protocol (Van Den Berghe et al ., 2001) for IIT provided guidance rather than strict instructions on insulin doses and required clinical judgements to be made while it was used. Other published protocols for intravenous insulin infusions have either had a higher target range of blood glucose (Woolfson, 1980; Brown and Dodek, 2001) or have not been evaluated in critical illness (McWilliam, 1980; George et al ., 1982; Thomas et al ., 1984; Watts et al ., 1987; Hendra and Yudkin, 1992; Malmberg et al ., 1994; Umpierrez et al ., 1997). To remove the need for clinical judgement (and the inherent errors it evokes), we decided to develop a nurse‐lead prescriptive insulin infusion protocol to be used for IIT on all of our critical care patients.…”