The prebiotic potential of polysaccharides and extracts of seaweeds

Ts, Zaporozhets; Беседнова, Н. Н.; Кузнецова, Т. А.; Zvyagintseva, T. N.; Макаренкова, И. Д.; Kryzhanovsky, Sergey P.; Mel'nikov, V. G.

doi:10.1134/s1063074014010106

Cited by 82 publications

(58 citation statements)

References 34 publications

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“…Thus, clarifying the effect of dietary fucoidan on gut microbiota would significantly benefit the elucidation of its functional mechanisms. Besides, fucoidan has also been documented to have certain prebiotic potentials by stimulating the growth of Bifidobacterium longum and Bifidobacterium bifidum 18 . in the colon of piglets 16,17 .…”

Section: Introductionmentioning

confidence: 99%

Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance ofLactobacillusandRuminococcaceae

et al. 2016

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Recently, fucoidan has been proposed as a potential prebiotic agent for functional food and pharmaceutical development. However, while previous studies illustrated favorable modulations of gut microbiota by fucoidan, changes in the overall microbial structure remain elusive. In the present study, modulations of gut microbiota by different fucoidans were studied using high throughput sequencing and bioinformatics analysis. We found that at the expense of opportunistic pathogenic bacteria such as Peptococcus, the abundance of beneficial bacteria including Lactobacillus and Ruminococcaceae was significantly increased in response to fucoidan treatment. Besides, by maintaining a more balanced composition of gut microbiota, dietary fucoidan also significantly reduced the antigen load and the inflammatory response in the host as evidenced by the decreased serum lipopolysaccharide-binding protein levels. Collectively, our results indicate that fucoidan can be used as a gut microbiota modulator for health promotion and treatment of intestinal dysbiosis.

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Section: Introductionmentioning

confidence: 99%

Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance ofLactobacillusandRuminococcaceae

et al. 2016

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“…The soluble fibers are alginates, fucans, and laminarans for brown seaweeds (Phaeophyta), whereas the soluble fibers are sulfated galactans (agars and carrageenans), xylans, and floridean starch for red seaweeds (Rhodophyta) (Kraan ). Green algae contain starch, xylans, mannans, and ionic polysaccharides which contain sulfate groups (Zaporozhets and others ). Uronic acids, rhamnose, xylose, galactose, and arabinose are also found in this type of algae (Bocanegra and others ).…”

Section: Marine Bioactive Ingredientsmentioning

confidence: 99%

Marine Bioactive Compounds and Their Health Benefits: A Review

Hamed

Özoğul

et al. 2015

Comp Rev Food Sci Food Safe

348

241

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The significance of marine creatures as a source of unique bioactive compounds is expanding. Marine organisms constitue nearly half of the wordwide biodiversity; thus, oceans and sea present a vast resource for new substances and it is considered the largest remaining reservoir of beneficial natural molecules that maight be used as functional constituents in the food sector. This review is an update to the information about recent functional seafood compounds (proteins, peptides, amino acids, fatty acids, sterols, polysaccharides, oligosaccharides, phenolic compounds, photosynthetic pigments, vitamins, and minerals) focusing on their potential use and health benefits.

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“…Better understanding of the benefits of prebiotics has urged a need to search for and develop new and alternative sources of prebiotics. According to Zaporozhets et al (2014), the prebiotic activity of extracts or of polysaccharides from marine seaweeds, combined with a broad spectrum of biological properties, evidences great potential for their use as functional nutrition ingredients enabling modulation of intestinal microbiota and of gastrointestinal tract (GIT) inflammation as well as normalization of the immune system. Therefore the main objective in this study was to evaluate the potential of the digested (closely simulating physiological conditions) seaweed and mushroom extracts containing different polysaccharide and oligosaccharide structures on gut microbial ecology.…”

Section: Introductionmentioning

confidence: 99%

In vitro fermentation and prebiotic potential of selected extracts from seaweeds and mushrooms

Rodrigues

Walton

Sousa

et al. 2016

LWT

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a b s t r a c tExtracts with prebiotic activity or bioactive compounds from natural sources such as seaweeds or mushrooms, combining a broad spectrum of biological properties, may offer great potential for their use as functional ingredients enabling intestinal microbiota modulation. In this context, selected enzymatic extracts from Sargassum muticum, Osmundea pinnatifida and Pholiota nameko were evaluated in vitro. Faecal fermentations were conducted anaerobically under controlled temperature and pH over 24 h. Enzymatic extracts of Ph. nameko and of O. pinnatifida at 1% (w/v), lead to increases in Bifidobacterium spp. after 6 h of fermentation in comparison to negative control, suggesting a stimulatory effect. No significant changes over 24 h were observed of Lactobacillus spp. In particular, the Ph. nameko extract obtained with Flavourzyme not only stimulated growth and/or activity of Bifidobacterium spp. but also led to a decrease of Clostridium histolyticum group upon 24 h, thus potentially benefiting colonic health. Higher percentages of this extract (2 and 3%) impaired a C. histolyticum reduction confirming this selective action and prebiotic potential. Differences in short chain fatty acids (SCFA) and lactic acid production between the four extracts may indicate a potential relationship between their physico-chemical properties, which differ in composition and structures, and modulation of gut bacterial species.

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The prebiotic potential of polysaccharides and extracts of seaweeds

Cited by 82 publications

References 34 publications

Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance ofLactobacillusandRuminococcaceae

Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance ofLactobacillusandRuminococcaceae

Marine Bioactive Compounds and Their Health Benefits: A Review

In vitro fermentation and prebiotic potential of selected extracts from seaweeds and mushrooms

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