2019
DOI: 10.1007/s10488-019-00990-7
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The Predicted Long-Term Benefits of Ensuring Timely Treatment and Medication Adherence in Early Schizophrenia

Abstract: The impact of initiatives aimed at reducing time in untreated psychosis during early-stage schizophrenia will be unknown for many years. Thus, we simulate the effect of earlier treatment entry and better antipsychotic drug adherence on schizophreniarelated hospitalizations, receipt of disability benefits, competitive employment, and independent/family living over a ten-year horizon. We predict that earlier treatment entry reduces hospitalizations by 12.6-14.4% and benefit receipt by 7.0-8.5%, while increasing … Show more

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Cited by 7 publications
(10 citation statements)
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References 43 publications
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“…After titles and abstracts were reviewed, 36 full texts were assessed. Among these, 17 studies were ultimately included in the final review along with two other articles obtained from additional sources (i.e., Google search), [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40] for a total of 19 studies (see Figure 1). As a result, there was an 8.4% (19/227) of relevant hits.…”
Section: Study Selectionmentioning
confidence: 99%
See 2 more Smart Citations
“…After titles and abstracts were reviewed, 36 full texts were assessed. Among these, 17 studies were ultimately included in the final review along with two other articles obtained from additional sources (i.e., Google search), [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40] for a total of 19 studies (see Figure 1). As a result, there was an 8.4% (19/227) of relevant hits.…”
Section: Study Selectionmentioning
confidence: 99%
“…As a result, there was an 8.4% (19/227) of relevant hits. The studies retrieved could be grouped into two groups: studies on existing economic-demographic models that included a component on mental health, [22][23][24][25][26][27][28][29][30][31][32] such as the Health&WealthMOD [22][23][24][25][26][27] and the Future Americans Model, 29 used to answer research questions on mental health (n = 11), and studies focused solely on mental health models developed to examine the impact of specific policies and/or interventions on mental disorders [33][34][35][36][37][38][39][40] (e.g., to understand the impact of social media on post-traumatic stress disorder (PTSD), examine the impact of smoking cessation initiatives among individuals with severe mental illness, or determine disease prevalence) (n = 8).…”
Section: Study Selectionmentioning
confidence: 99%
See 1 more Smart Citation
“…Therefore, there is a need for training as well as for liaising with relevant agencies that act as advocates for those diagnosed with SMI. Prior studies have highlighted the importance of ensuring timely treatment from those diagnosed with SMI (Horvitz‐Lennon et al, 2020). In contrast, our findings highlight the unfortunate factors (e.g.…”
Section: Conclusion and Relevance For Clinical Practicementioning
confidence: 99%
“…The reasons why people do not take medication as prescribed are complex [ 7 , 8 , 9 ] and may vary between patients and within the same individual over time. Perhaps the most important factors affecting adherence in young people with early psychosis that are reported in the literature are the duration of untreated symptoms [ 10 , 11 ], substance use (addiction) [ 3 , 11 ], lack of insight (not accepting the symptoms as part of mental ill-health) [ 4 , 12 ], medication-related side effects [ 3 , 13 ] and lack of social support [ 4 , 14 ].…”
Section: Introductionmentioning
confidence: 99%