The Predictive Role of Genetic Markers in the Different Types Diabetes -- Related Complications

Pashkunova, S.V.

doi:10.12732/ijam.v35i5.7

Cited by 1 publication

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“…Indicators were studied once in peripheral venous blood. The two groups were balanced according to demographic and clinical indicators, comorbidity was reduced only to hypertension and diabetes mellitus [14,15], ensuring maximum balance between the groups and objective comparison of the obtained results. The unidirectional and logically interrelated deviations in hemostatic markers gave us indisputable grounds to assume that significant systemic hypercoagulability occured during short PAF episodes (duration ≤ 24 hours) [11,12,13].…”

Section: Study Design and Target Populationmentioning

confidence: 99%

Thromboembolic Stroke Predictors in Paroxysmal Atrial Fibrillation: Cox Modeling Basedon Studied Hemostasis Indicators

Negreva¹

2023

Int. J. of Appl. Math.

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Thromboembolic stroke in paroxysmal atrial fibrillation (PAF) is associated with high disability and mortality, therefore its prediction is extremely important for clinical practice. The coagulation and fibrinolytic systems are the key factors, responsible for thrombus formation in atrial fibrillation. In this sense, it is reasonable to search for thromboembolic stroke predictors among coagulation and fibrinolytic indicators in PAF patients. This determined the aim of our study, namely to study the predictive value for thromboembolic stroke of twenty coagulation and fibrinolytic indicators in PAF patients. In this article, overall survival until stroke onset was modeled using the Kaplan-Meier curve. Multivariate Cox regression analysis was used to investigate the relationship between survival time and twenty coagulation and fibrinolytic parameters measured in 51 patients. Significant predictive value (p < 0.05) was found for plasma TF levels (HR 1.

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