“…Dispositional negativity is robustly associated with some of the most common and burdensome mental illnesses, including anxiety disorders, depression, and co-morbid substance abuse (e.g., Castellanos-Ryan et al, 2016; Davis et al, 2018; Hayes, Osborn, Lewis, Dalman, & Lundin, 2017; Hengartner, Tyrer, Ajdacic-Gross, Angst, & Rossler, 2018; Kendler et al, in press; Navrady et al, 2017; Paulus, Backes, Sander, Weber, & von Gontard, 2015; Seeboth & Mottus, 2018; Shackman et al, 2016c). Longitudinal work shows that individuals with elevated levels of dispositional negativity are more likely to develop internalizing (i.e., anxiety and mood) disorders in the future (e.g., Buzzell et al, 2017; Clark, Durbin, Hicks, Iacono, & McGue, in press; Goldstein, Kotov, Perlman, Watson, & Klein, 2018; Klein & Mumper, 2018; Luan et al, in press; Struijs et al, 2018; Wichstrom, Penelo, Rensvik Viddal, de la Osa, & Ezpeleta, 2018; Zinbarg et al, 2016). The magnitude of these prospective associations is substantial.…”