The Predictive Value of Head Circumference Growth during the First Year of Life on Early Child Traits

Dupont, Caroline; Castellanos‐Ryan, Natalie; Séguin, Jean R.; Muckle, Gina; Simard, Marie-Noëlle; Shapiro, Gabriel D.; Herba, Catherine M.; Fraser, William D.; Lippé, Sarah

doi:10.1038/s41598-018-28165-8

Cited by 69 publications

(36 citation statements)

References 76 publications

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“…Length-for-age z score 4.0 <0.001 2.4, 5. in which Nepal was one of the site (Scharf et al, 2018), however, some studies contradict to the consistencies of results associated with head circumference and cognitive development (Martyn et al, 1996;Dupont et al, 2018). We expected head circumference to show a more overall association across domains in the current study, there was, however, a lack of such associations.…”

Section: P-value 95% Confidence Interval Betacontrasting

confidence: 51%

Determinants of Cognitive Development in the Early Life of Children in Bhaktapur, Nepal

et al. 2019

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Background: Children in low and middle income countries may have many risk factors for poor cognitive development, and are accordingly at a high risk of not reaching their developmental potential. Determinants for cognitive development in early life can be found among biological and socioeconomic factors, as well as in stimulation and learning opportunities.Objective: The present study aimed to identify determinants of cognitive, language and motor development in 6-11 months old Nepalese infants.Methods: Six hundred infants with a length-for-age z-score <-1 were assessed with the Bayley Scales of Infant and Toddler development, 3rd edition (Bayley-III). Information on socioeconomic factors, child and maternal demographics, clinical and biological factors, and the home environment were collected. In a manual stepwise variable selection procedure, we examined the association between selected biological, socioeconomic and stimulation and learning opportunity variables and the Bayley-III cognitive, language and motor development subscale scores in multiple linear regression models. Results:The length-for-age z-scores was positively associated with the cognitive composite score [standardized beta (ß): 0.22, p < 0.001] and the motor composite score [(ß): 0.14, p = 0.001]. Children born with low birth weight (<2500 g) scored significantly lower on all subscale scores. Diarrheal history was associated with poor language composite scores, and females had higher language composite scores than boys [(ß): 0.11, p = 0.015]. Children who had been hospitalized during the first month of life had also lower cognitive and motor composite scores than those who had not been hospitalized. Parental reports of physical punishment and lack of spontaneous vocalization were associated with poor cognitive and language composite

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Section: P-value 95% Confidence Interval Betacontrasting

confidence: 51%

Determinants of Cognitive Development in the Early Life of Children in Bhaktapur, Nepal

et al. 2019

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“…Dupont el al. (47) investigated the predictive value of head circumference during the first year of life on early child development. They demonstrated that post-natal head circumference growth positively predicted gross motor skills as well as behavioral growth at 2 years of age.…”

Section: Discussionmentioning

confidence: 99%

Human Milk Glucocorticoid Levels Are Associated With Infant Adiposity and Head Circumference Over the First Year of Life

et al. 2020

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Human milk (HM) is a complex and dynamic biological fluid, which contains appreciable concentrations of the glucocorticoids, cortisol and cortisone. Experimental studies in non-human primates suggest the HM glucocorticoids' impact on infant growth and body composition. In this current study, analysis is made of the relationships between HM glucocorticoid concentrations and the infant growth and development over the first year of life. HM was collected by lactating healthy women (n = 18), using a standardized protocol, at 2, 5, 9, and 12 months after childbirth. Cortisol and cortisone concentrations in the HM were measured using liquid chromatography mass spectrometry. Infant weight, length and head circumference were measured by standard protocols and percentage fat mass (% FM) determined by whole body bioimpedance. Cortisol and cortisone concentrations were unaltered over the analyzed lactation period (2-12 months), and were altered by infant sex. Although, HM cortisol was positively associated with infant percentage fat mass (% FM) (p = 0.008) and cortisone positively associated with infant head circumference (p = 0.01). For the first 12 months of life, the concentration of HM glucocorticoids levels was positively associated with infant adiposity (%FM) and head circumference. This preliminary evidence provides insight to a possible relationship between ingested HM glucocorticoids and infant body composition. Further studies are required to determine the mechanisms regulating HM glucocorticoids.

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“…The relatively smaller head circumference, albeit within the normal range, in the first months of life with rapid catchup growth by the end of the first year of life may have long-term implications. A recent report documented that the growth of head circumference is a surrogate marker of brain development, and that atypical head circumference growth is associated with neurodevelopmental disorders 43 . Conditions affecting the intrauterine environment were linked to maternal hormonal changes; even mild and transient changes capable of affecting the expression of target genes were reportedly involved in brain growth and maturation 44,45 .…”

Section: Discussionmentioning

confidence: 99%

Mild maternal sleep-disordered breathing during pregnancy and offspring growth and adiposity in the first 3 years of life

Brener

Lebenthal

Levy

et al. 2020

Sci Rep

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Sleep-disordered breathing (SDB) during pregnancy has been linked to adverse fetal outcomes. Since the intrauterine milieu plays a critical role in childhood growth, we explored the interactions between maternal SDB and offspring growth and adiposity patterns during infancy. Fifty-eight healthy women with uncomplicated pregnancies underwent an objective sleep study and laboratory evaluation during the third trimester, their offspring underwent a 3-year growth surveillance. The 14 (24.1%) women with SDB had a higher body mass index (BMI) (P = 0.003), elevated C-reactive protein levels (P = 0.003), and decreased HDL-cholesterol levels (P = 0.009) than the women without SDB. A general linear model evaluated the interactions between maternal SDB and offspring growth and adiposity measurements after controlling for gestational age and maternal and paternal BMIs. The offspring of mothers with SDB had a significantly smaller head circumference at birth (P = 0.004), with a distinctive pattern of catchup growth by the end of the first year of life (P = 0.018). Their growth pattern was distinguished by compromised birth weight-to-length, rapid catch-up growth, and an increase in both weight-to-length and triceps thickness by the age of three (P < 0.001 and P = 0.001, respectively). Our findings suggest that maternal SDB during pregnancy affects head circumference growth and adiposity acquisition from birth through infancy.

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The Predictive Value of Head Circumference Growth during the First Year of Life on Early Child Traits

Cited by 69 publications

References 76 publications

Determinants of Cognitive Development in the Early Life of Children in Bhaktapur, Nepal

Determinants of Cognitive Development in the Early Life of Children in Bhaktapur, Nepal

Human Milk Glucocorticoid Levels Are Associated With Infant Adiposity and Head Circumference Over the First Year of Life

Mild maternal sleep-disordered breathing during pregnancy and offspring growth and adiposity in the first 3 years of life

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