The predictive value of plasma osmolality for in‐hospital mortality in patients with acute pulmonary embolism

Öztaş, Selvi; Çınar, Tufan; Hayıroğlu, Mert İlker; Avşar, Şahin; Keskin, Muhammed; Orhan, Ahmet Lütfüllah

doi:10.1111/crj.13001

Cited by 20 publications

(16 citation statements)

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“…Instead, since medium- and long-term follow-up mortality is mainly driven by comorbidities, CCI represent the most appropriate predictor of death, whith sPESI losing its prognostic value. These data are in keeping with other studies' results which found that in PE patients mortality was associated with variables not strictly related to the acute index event, such as plasma osmolality and nutritional indexes [ 24 , 25 ].…”

Section: Discussionsupporting

confidence: 92%

Predictors of medium- and long-term mortality in elderly patients with acute pulmonary embolism

Friz

Orenti

Gelfi

et al. 2020

Heliyon

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Introduction Data on medium- and long-term prognostic factors for death in elderly patients with acute Pulmonary Embolism (APE) are lacking. The present study aimed to assess sPESI score and the Charlson Comorbidity Index (CCI) as medium- and long-term predictors of mortality in elderly patients with haemodinamically stable APE. Methods All consecutive patients aged≥65 years old, evaluated at the emergency department (ED) of our hospital from 2010 through 2014, with a final diagnosis of APE, were included in this retrospective cohort study. Results Study population:162 patients, female:36.5%, median age:79 years old, 74% presented a sPESI score>0, and 61% a CCI≥ 1. All causes mortality: 19.8%, 23.5%, 26.5%, 32.1% and 48.2% at 3, 6 months, 1, 2 and 5 years after APE. Univariate regression analysis: CCI≥1 was associated with a higher mortality at 3, 6 months, 1, 2 and 5 years. Multivariate Cox analysis: CCI≥1 associated with increased mortality at 3 months (HR:4.29; IC95%:1.46–12.59), 6 months (HR:5.33; IC95%:1.84–15.44), 1 year (HR:4.87; IC95%:1.87–12.70), 2 years (HR:3.78; IC95%:1.74–8.25), and 5 years (HR:2.30; IC95%:1.33–3.99). sPESI score≥1 was not found to be related to an increased medium-or long-term mortality. Negative predictive values (IC95%) of CCI≥1 were 93.65% (87.61–99.69), 93.65% (87.61–99.69), 92.06% (85.37–98.76), 87.3% (79.05–95.55) and 71.61% (60.13–83.1) for mortality at 3, 6 months, 1, 2 and 5 years. Conclusion In elderly patients with a confirmed normotensive APE, unlike sPESI score, CCI showed to be an independent prognostic factor for medium- and long-term mortality. In these patients, after the acute phase following a PE event, the assessment of the comorbidities burden represents the most appropriate approach for predicting medium- and long-term mortality.

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Section: Discussionsupporting

confidence: 92%

Predictors of medium- and long-term mortality in elderly patients with acute pulmonary embolism

Friz

Orenti

Gelfi

et al. 2020

Heliyon

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“…Данные показатели могут рассматриваться как фактор высокого риска тромботических осложнений у данной категории пациентов [13]. Повышение осмолярности плазмы у пациентов с ТЭЛА можно рассматривать как предиктор госпитальной смертности [14].…”

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Diabetes mellitus and thrombotic complications

Vasil'ceva¹,

Vitt²

2019

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In the article the analysis of treatment of 169 newborns with generic volume hemorrhage of the scalp in the form of kefalohematomas, subaponeurotic hematomas and epiduralsubperiosteal hematomas for the period 2014-2018. Higher risk of complications defines the active tactics with a focus on early puncture aspiration of the hematoma in medium to large sizes (after 3-5 days) within the dermal-aponeurotic segments and recommended areas of puncture.

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Section: рисунок 2 -зависимость относительного содержания моноцитов оunclassified

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2019

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В сборнике научных трудов собраны материалы из различных областей научных знаний. В данном издании приведены все материалы, которые были присланы на XIX международную научно-практическую конференцию Научный диалог: Вопросы медицины Сборник предназначен для научных работников, преподавателей, аспирантов и студентов. Все материалы, размещенные в сборнике, опубликованы в авторском варианте. Редакция не вносила коррективы в научные статьи. Ответственность за информацию, размещенную в материалах на всеобщее обозрение, несут их авторы. Информация об опубликованных статьях будет передана в систему Российского индекса научного цитирования (РИНЦ) и наукометрическую базу SPINDEX Электронная версия сборника доступна на сайте ЦНК МОАН. Сайт центра: conf.sciencepublic.ru УДК 61 ББК 5 SPLN 001-000001-0451-LJ http://conf.sciencepublic.ru

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The predictive value of plasma osmolality for in‐hospital mortality in patients with acute pulmonary embolism

Cited by 20 publications

References 22 publications

Predictors of medium- and long-term mortality in elderly patients with acute pulmonary embolism

Predictors of medium- and long-term mortality in elderly patients with acute pulmonary embolism

Diabetes mellitus and thrombotic complications

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