The Predisposing Pathology and Clinical Characteristics in the Scottish Retinal Detachment Study

Mitry, Danny; Singh, Jaswinder; Yorston, David; Siddiqui, Rehana; Wright, Alan F.; Fleck, Brian; Campbell, Harry; Charteris, David G.

doi:10.1016/j.ophtha.2010.11.031

Cited by 128 publications

(117 citation statements)

References 23 publications

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“…Algvere et al (1999) reported that history of cataract surgery was found in 30.8% of the eyes with RRD in Sweden. Similar findings with around 30% of patients having retinal detachment after cataract surgery were reported by Mitry et al (2011) The risk of suffering RRD after an uncomplicated cataract operation has been estimated to be approximately 1/1000 (Mitry et al, 2010).…”

Section: Epidemiology Of Pvd and Rrdsupporting

confidence: 83%

Ageing of the vitreous: From acute onset floaters and flashes to retinal detachment

Lumi¹,

Hawlina²,

Glavač³

et al. 2015

Ageing Research Reviews

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Section: Epidemiology Of Pvd and Rrdsupporting

confidence: 83%

Ageing of the vitreous: From acute onset floaters and flashes to retinal detachment

Lumi¹,

Hawlina²,

Glavač³

et al. 2015

Ageing Research Reviews

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“…4). Excessive gel liquefaction is observed in a number of circumstances such as with inborn errors in collagen metabolism (Stickler's, Marfan's, and Ehlers-Danlos syndromes) [89,90], intraocular inflammation [91,92], diabetes [93], ocular trauma [94], and in high myopia [75]. …”

Section: Posterior Vitreous Detachmentmentioning

confidence: 99%

The Vitreous, the Retinal Interface in Ocular Health and Disease

2013

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The vitreous is a complex structure whose composition and appearance change with age. Anomalous adhesions between the posterior vitreous face and the retinal surface are the cause of numerous vitreoretinal complications, while the presence of an intact posterior hyaloid provides a scaffold for vascular growth and anteroposterior traction. This review summarizes what is known about the biochemistry of the vitreous, the process of posterior vitreous detachment (PVD) development, and the available clinical approaches to examining the vitreous and its interface. A pooled analysis of studies looking at the presence of a complete, partial or absent PVD in a number of macular and retinal diseases allows us to establish odds ratios for these various states. From this emerge both protective and disease-associated states in conditions such as proliferative diabetic retinopathy, macular edema, and age-related macular degeneration. With the emergence of pharmacological means to separate the posterior hyaloid, a better understanding of the possible role of the vitreous in tractional syndromes is required.

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“…In another report from Scotland, GRT accounted for 1.3% of the total rhegmatogenous retinal detachments seen within a 2 year period [7]. The incidence of GRT with or without a retina detachment in an African population is not known.…”

Section: Discussionmentioning

confidence: 98%

Giant Retina Tear in an African Population: Presentation and Fellow Eyes

Okonkwo¹,

Hassan²,

Michael³

et al. 2017

OJOph

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Aim: To examine the profile and presentation of a consecutive series of giant retinal tears (GRTs) in an African population. Also to review the clinical state of the patient's fellow eyes. Method: A retrospective observational case series of thirty-six consecutive eyes of 36 patients with a GRT retina detachment that had vitreoretina surgery done between April 2006 and June 2013. All information was extracted from the patient's case records. Result: Thirty-nine case records had surgery consecutively within the study period. Three case records had incomplete data and were excluded from the analysis. Thirty-six eyes were analyzed. There were mostly males (80.6%), age range 21 -65 yrs (mean age 47 yrs). The commonest etiology was idiopathic (21 eyes). Presenting visual acuity was mostly in the counting finger and hand motion range (83%), and the mean presenting intraocular pressure was 6.8 mmHg. Most of the eyes presented with a total retina detachment (4 quadrant involvement; 56%), macular involvement (96%), commonest size of the retina tear being between 90 to 180 degrees in 20 eyes; rolled over retina flap (61%) and advanced grades of PVR being very common (83%). The commonest fellow eye event noted was blindness in 16 fellow eyes; while 12 eyes had prophylactic retina laser photocoagulation to peripheral predisposing retina lesions. Conclusion: The presentation of GRT in a low resource country is often as a complex retina detachment situation, which may arise from frequent delays to assess care and other socioeconomic issues. This carries significant implications on prognosis following surgical intervention. Also this study raises the awareness that fellow eyes of GRT in Africa are at increased risk of blindness and require more careful attention.

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The Predisposing Pathology and Clinical Characteristics in the Scottish Retinal Detachment Study

Cited by 128 publications

References 23 publications

Ageing of the vitreous: From acute onset floaters and flashes to retinal detachment

Ageing of the vitreous: From acute onset floaters and flashes to retinal detachment

The Vitreous, the Retinal Interface in Ocular Health and Disease

Giant Retina Tear in an African Population: Presentation and Fellow Eyes

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