The Prednisolone Glucose Tolerance Test in Pregnancy

Gc, Kyle; Yalçin, Saliha; Drewyer, R; Carruthers, Bruce M.

doi:10.2337/diab.13.6.572

Cited by 37 publications

(23 citation statements)

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“…The criteria of GDM diagnosis were initially established more than 50 years ago by O'Sullivan 11 . It had been used for about half a century in China with minor modifications 11–16 .…”

Section: Gdm Diagnostic Criteriamentioning

confidence: 99%

Comprehensive Management of Gestational Diabetes Mellitus in China

Wei

Juan

Yang

2021

Maternal-Fetal Medicine

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Gestational diabetes mellitus (GDM) is one of the most common medical conditions affecting pregnant women. GDM causes increasing concern to obstetricians, and it is associated with early complications and long-term effects for both mothers and their newborns. 1,2 After the twochild policy was fully implemented in China, the incidence of GDM increased further. The diagnostic criteria of GDM have continuously evolved since the emergence of new evidence. There are many important issues such as how to manage the large population of GDM in China, especially in the rural areas. It has been reported the risk of GDM among different ethnic groups is varied, and data from Chinese mainland are lacking in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study. 3 However, it has been proved that the GDM diagnostic criteria according to HAPO study was suitable for China. Here, we aim to focus on the challenges of diagnosis and management strategies for GDM and discuss the proper recommendations on the diagnosis and management of GDM in China.With the rapid socioeconomic and life-style transformation, the prevalence of GDM has risen dramatically in China. 4,5 GDM has become one of the most common problems that affect nearly one-fifth of all pregnant women in China. According to a study conducted in 15 hospitals in Beijing, the prevalence of GDM was 19.7%. 6 GDM has long-term consequences for both mothers and children, including increased risk for obesity, type 2 diabetes, and/or other metabolism syndromes in later life. 1,2 Therefore, it is important to have good glycemic control during pregnancy to prevent adverse pregnancy outcomes and promote maternal and neonatal health. One of the most important problem is how to manage so huge GDM population in China.

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“…The criteria of GDM diagnosis were initially established more than 50 years ago by O'Sullivan 11 . It had been used for about half a century in China with minor modifications 11–16 .…”

Section: Gdm Diagnostic Criteriamentioning

confidence: 99%

Comprehensive Management of Gestational Diabetes Mellitus in China

Wei

Juan

Yang

2021

Maternal-Fetal Medicine

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“…Jackson (19616) has used cortisone, while Kyle, Yalcin, Drewyer & Carruthers (1964), Joplin, Fraser & Keeley (1961) and Baldi, Nusimovitch, Mestman, Miro, Mir & Villafane (1961) used prednisolone. Jackson (19616) has used cortisone, while Kyle, Yalcin, Drewyer & Carruthers (1964), Joplin, Fraser & Keeley (1961) and Baldi, Nusimovitch, Mestman, Miro, Mir & Villafane (1961) used prednisolone.…”

Section: The Diabetogenic Effect Of Pregnancy On the Mothermentioning

confidence: 99%

Some Aspects of Carbohydrate Metabolism in Pregnancy With Special Reference to the Energy Metabolism and Hormonal Status of the Infant of the Diabetic Woman and the Diabetogenic Effect of Pregnancy

Baird¹

1969

Journal of Endocrinology

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“…It is commonly defined as the very first recognition of diabetes or impaired glucose tolerance during pregnancy. However, there is no universally accepted protocol to diagnose GDM (1)(2)(3). According to the report of the International Diabetes Federation (IDF) in 2019, 16.7% of live births were affected by hyperglycemia in pregnant women and 84% of them had gestational diabetes (4).…”

Section: Introductionmentioning

confidence: 99%

The therapeutic effects of attending a one-day outpatient service on patients with gestational diabetes and different pre-pregnancy body mass indices

Cao¹,

Ma²,

Wang³

et al. 2023

Front. Public Health

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PurposeThis study investigated the effects of attending a one-day outpatient service on the outcomes of patients with gestational diabetes mellitus (GDM) and different pre-pregnancy body mass indices (BMIs).MethodsThe study recruited 311 pregnant women with GDM into a one-day outpatient service at The Fourth Hospital of Shijiazhuang from September 2019 to December 2021. They were randomly assigned to three groups, based on their pre-pregnancy BMI as follows: group A, BMI < 18.5 kg/m2; group B, 18.5 ≥ BMI > 25.0 kg/m2; group C, BMI ≥25 kg/m2. The following information was collected from all the participants: fasting blood glucose, hemoglobin A1c (HbA1C), insulin dose, gestational weight gain, weight gain after the one-day outpatient service, and perinatal outcomes.ResultsThe three groups showed significant differences in fasting blood glucose and HbA1C, insulin treatment rate, and the incidence of pregnancy hypertension/preeclampsia and neonatal jaundice (all P < 0.05). The rate of excessive gestational weight gain in all of the groups also reflected significant differences (P < 0.05). Group A showed the lowest weight gain, while group C gained the most weight. There is no significant difference in the incidences of hypertension/preeclampsia, neonatal jaundice, or premature birth between patients with weight loss/no weight gain and those with positive weight gain.ConclusionOne-day diabetes outpatient integrated management may effectively help to manage weight gain and blood glucose in patients with GDM and different pre-pregnancy BMIs. Dietary control after a GDM diagnosis may have helped to avoid weight gain entirely, as well as negative weight gain, but did not increase the risk of maternal and infant-related complications.

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The Prednisolone Glucose Tolerance Test in Pregnancy

Cited by 37 publications

References 0 publications

Comprehensive Management of Gestational Diabetes Mellitus in China

Comprehensive Management of Gestational Diabetes Mellitus in China

Some Aspects of Carbohydrate Metabolism in Pregnancy With Special Reference to the Energy Metabolism and Hormonal Status of the Infant of the Diabetic Woman and the Diabetogenic Effect of Pregnancy

The therapeutic effects of attending a one-day outpatient service on patients with gestational diabetes and different pre-pregnancy body mass indices

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