The PrEP Care Continuum and Black Men Who Have Sex with Men: A Scoping Review of Published Data on Awareness, Uptake, Adherence, and Retention in PrEP Care

Ezennia, Ogochukwu; Geter, Angelica; Smith, Dawn K.

doi:10.1007/s10461-019-02641-2

Cited by 106 publications

(87 citation statements)

References 54 publications

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“…However, a gap remains concerning the impact of PrEP for HIV prevention on Black adults with CJI. Previous research (24,39,40) has shown that PrEP awareness and acceptability is shaped by individual, social and sexual network, and community level factors, which in turn, should be leveraged to promote PrEP uptake and adherence among CJI adults. Given the emerging literature, innovative strategies and interventions designed to implement PrEP must consider the relevant factors in uencing PrEP awareness.…”

Section: Resultsmentioning

confidence: 99%

“…Research further indicates that any signi cant increase in PrEP coverage among Black persons, particularly among MSM, would decrease the racial disparity gap in HIV incidence by at least 50% (19). The limited use of PrEP among Black adults may be explained by multifaceted factors such as low awareness (20), low HIV risk perception (21)(22)(23), HIVrelated stigma (21,24,25), health care provider biases (26), distrust for medical systems (23,25), and medicationrelated concerns such as side effects and cost (22,25,26). These barriers have hindered efforts to improve PrEP utilization within the population.…”

Section: Introductionmentioning

confidence: 99%

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Factors Correlated with Pre-Exposure Prophylaxis (PrEP) Awareness and Use among Black Adults in the United States: Implications for Improving PrEP Uptake

Wilson

Przybyla

Gabriel

et al. 2021

Preprint

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In the United States, low rates of pre-exposure prophylaxis (PrEP) awareness and utilization persist among Black adults. To date, few studies have assessed PrEP awareness and use among a nationally representative sample of Black adults. The present study explored factors associated with PrEP awareness and use among Black adults in the United States. Most participants were unaware of PrEP (71%). Those reporting a history of incarceration [aOR 1.73 (1.04, 2.90), p <.05] and lifetime sexually transmitted infection testing [aOR 1.76 (1.19, 2.59), p <.05] had greater odds of awareness. In the sample, only 6% of participants had ever taken PrEP. Those with a history of incarceration [aOR 9.96 (2.82, 35.14), p <.05], concurrent sexual partners [aOR 1.09 (1.00, 1.18), p <.05], and substance use during sex [aOR 4.23 (1.02, 17.48), p <.05] had greater odds of use. Interventions to improve PrEP uptake among Black adults must consider the contextual factors associated with awareness and use.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Factors Correlated with Pre-Exposure Prophylaxis (PrEP) Awareness and Use among Black Adults in the United States: Implications for Improving PrEP Uptake

Wilson

Przybyla

Gabriel

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Although a challenge in higher-risk populations [43–45], several interventions have been proven effective at improving the PrEP cascade [46–48]. Our model suggests that in an epidemiological context like San Francisco, where HIV incidence has declined since the 1990s and HIV prevalence has fallen since 2012 [42], increasing PrEP retention would still further reduce HIV incidence.…”

Section: Discussionmentioning

confidence: 99%

Population Impact and Efficiency of Improvements to HIV PrEP Under Conditions of High ART Coverage among San Francisco Men Who Have Sex with Men

Guillou¹,

Buchbinder²,

Scott³

et al. 2021

Preprint

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Background: Key components of Ending the HIV Epidemic (EHE) plan include increasing HIV antiretroviral therapy (ART) and HIV preexposure prophylaxis (PrEP) coverage. One complication to addressing this service delivery challenge is the wide heterogeneity of HIV burden and healthcare access across the U.S. It is unclear how the effectiveness and efficiency of expanded PrEP will depend on different baseline ART coverage. Methods: We used a network-based model of HIV transmission for men who have sex with men (MSM) in San Francisco. Model scenarios increased varying levels of PrEP coverage relative under current empirical levels of baseline ART coverage and two counterfactual levels. We assessed the effectiveness of PrEP with the cumulative percent of infections averted (PIA) over the next decade and efficiency with the number needed to treat (NNT) by PrEP required to avert one HIV infection. Results: In our projections, only the highest levels of combined PrEP and ART coverage achieved the EHE goals. Increasing PrEP coverage up to 75% showed that PrEP effectiveness was higher at higher baseline ART coverage with the PIA ranging from 61% in the lowest baseline ART coverage population to 75% in the highest ART coverage. The efficiency declined with increasing ART (NNT range from 41 to 113). Conclusions: Improving both PrEP and ART coverage would have a synergistic impact on HIV prevention even in a high baseline coverage city like San Francisco. Efforts should focus on narrowing the implementation gaps to achieve higher levels of PrEP retention and ART sustained viral suppression.

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“…Solutions addressing PrEP or PEP adherence that researchers have examined include social networks (Kuhns et al, 2017;Garcia et al, 2016) and telehealth solutions (Klausner and CFAR Development Core, 2018;Youth Tech Health, 2018). With the former, there has not been any evidence that shows that social networks can address adherence or awareness (Ezennia et al, 2019), and with the latter, telehealth solutions are limited to the availability of a professional and may not be cost effective (Touger and Wood, 2019). Having an automated agent that can provide real-time and high availability to counsel and inform patients may offer an alternative, but further research is needed to foresee this possibility.…”

Section: Discussionmentioning

confidence: 99%

Towards an Ontology-based Medication Conversational Agent for PrEP and PEP

Amith

Cui

Roberts

et al. 2020

Proceedings of the First Workshop on Natural Language Processing for Medical Conversations

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HIV (human immunodeficiency virus) can damage a human's immune system and cause Acquired Immunodeficiency Syndrome (AIDS) which could lead to severe outcomes, including death. While HIV infections have decreased over the last decade, there is still a significant population where the infection permeates. PrEP and PEP are two proven preventive measures introduced that involve periodic dosage to stop the onset of HIV infection. However, the adherence rates for this medication is low in part due to the lack of information about the medication. There exist several communication barriers that prevent patient-provider communication from happening. In this work, we present our ontologybased method for automating the communication of this medication that can be deployed for live conversational agents for PrEP and PEP. This method facilitates a model of automated conversation between the machine and user can also answer relevant questions.

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The PrEP Care Continuum and Black Men Who Have Sex with Men: A Scoping Review of Published Data on Awareness, Uptake, Adherence, and Retention in PrEP Care

Cited by 106 publications

References 54 publications

Factors Correlated with Pre-Exposure Prophylaxis (PrEP) Awareness and Use among Black Adults in the United States: Implications for Improving PrEP Uptake

Factors Correlated with Pre-Exposure Prophylaxis (PrEP) Awareness and Use among Black Adults in the United States: Implications for Improving PrEP Uptake

Population Impact and Efficiency of Improvements to HIV PrEP Under Conditions of High ART Coverage among San Francisco Men Who Have Sex with Men

Towards an Ontology-based Medication Conversational Agent for PrEP and PEP

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