The preparation and some physical properties of ten methyl dithiastearate isomers

Synthesis and a study of the 13C NMR spectroscopic properties of positional isomers of some C18 acetylenic thia fatty esters

“…8 Skrede et al have reviewed the metabolism of thia fatty acids. 9 Our group have synthesized and studied spectroscopic and mass spectrometric properties of the positional isomers of the methyl thialaurate, [10][11][12][13] ten methyl dithiastearate isomers 14 and the corresponding sulfinyl and sulfonyl derivatives of methyl thialaurate. 15 In this paper, we describe the synthesis of a set of positional isomers of C 18 acetylenic thia fatty esters (5-8, Scheme 1) in an effort to study the effect of the sulfur atom on the chemical shifts of the carbon nuclei in the alkynyl chain of these thia fatty ester isomers by nuclear magnetic resonance spectroscopy.…”