The preparation of hybrid silicon quantum dots by one-step synthesis for tetracycline detection and antibacterial applications

Chi, Yuting; Sun, Wanlin; Zhou, Lijia; Pei, Shuchen; Zeng, Haichun; Cheng, Yunying; Chai, Shuiqin

doi:10.1039/d2ay02102a

Cited by 3 publications

(1 citation statement)

References 55 publications

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“…Quantum dots (QDs) are widely used in the eld of sensing [18][19][20][21] due to their excellent optical properties such as a broad excitation spectrum, a narrow emission spectrum, adjustable emission wavelength, and resistance to photobleaching. At present, various uorescent materials including semiconductor QDs, [22][23][24] carbon dots 25,26 and silicon QDs 27,28 have been used for uorescence detection of TC. However, the uorescence quantum yield of conventional QDs is low, and the sensitivity of the sensor will decrease aer surface modication.…”

Section: Introductionmentioning

confidence: 99%

Construction of a stable fluorescent sensor based on CsPbBr₃/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol

He,

Li,

Wang

et al. 2024

Anal. Methods

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Section: Introductionmentioning

confidence: 99%

Construction of a stable fluorescent sensor based on CsPbBr₃/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol

He,

Li,

Wang

et al. 2024

Anal. Methods

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Broad-Spectrum Bactericidal Multifunctional Tiny Silicon-Based Nanoparticles Modified with Tannic Acid for Healing Infected Diabetic Wounds

Shen,

Jia,

Zeng

et al. 2024

ACS Appl. Mater. Interfaces

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Infected chronic wounds, in particular, diabetic wounds, are hard to heal, posing a global health concern with high morbidity and mortality rates. Diabetic full-thickness wounds infected with E. coli belong to the most difficult to heal chronic infected wounds. Here, we introduced tannic acid-modified siliconbased nanoparticles (TA-SiNPs) with broad-spectrum bactericidal activity that bacteria develop minimal resistance to, and they can effectively treat full-thickness wounds in diabetic mice infected with E. coli. Our findings indicate that these TA-SiNPs could achieve 100% antibacterial efficiency against S. aureus and 99.83% against E. coli, underlied by a positive surface charge and tannic acid groups facilitating bacterial membrane chemical composition depletion and depolarization of the membrane. In addition, we showed that spraying TA-SiNPs onto the skin wound of diabetic mice infected with E. coli resulted in wound healing with 98% closure after 12 days, in stark contrast to 49% of the control (PBS) and 68% of the one treated with Ofloxacin. Along with infection inhibition and ROS scavenging, we identified cell proliferation stimulation, inflammatory cytokine downregulation, and healing cytokine upregulation in the lesion, favoring the healing process. This study not only demonstrates the feasibility of employing silicon-based nanoparticles in diabetic wound healing for the first time, but also reports the first broad-spectrum bactericidal silicon nanodots. Furthermore, this provides novel insights into the mechanism of tannin-based nanoparticles disrupting bacterial membranes by depleting their chemical constituents. Our results highlighted that the developed TA-SiNPs are an effective nanomaterial for treating the infected chronic wounds.

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Indocalamus Leaves Carbon Dots as a Potential Antibacterial Agent

Liu,

Sun,

et al. 2023

Russ J Gen Chem

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The preparation of hybrid silicon quantum dots by one-step synthesis for tetracycline detection and antibacterial applications

Abstract: In this study, we prepared three different silicon quantum dots (SiQDs-1, SiQDs-2 and SiQDs-3) by hydrothermal synthesis with rose Bengal as the reducing agent and triacetoxy(methyl)silane and allyloxytrimethylsilane as silicon sources.

Cited by 3 publications

References 55 publications

Construction of a stable fluorescent sensor based on CsPbBr₃/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol

Construction of a stable fluorescent sensor based on CsPbBr₃/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol

Broad-Spectrum Bactericidal Multifunctional Tiny Silicon-Based Nanoparticles Modified with Tannic Acid for Healing Infected Diabetic Wounds

Indocalamus Leaves Carbon Dots as a Potential Antibacterial Agent

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The preparation of hybrid silicon quantum dots by one-step synthesis for tetracycline detection and antibacterial applications

Abstract: In this study, we prepared three different silicon quantum dots (SiQDs-1, SiQDs-2 and SiQDs-3) by hydrothermal synthesis with rose Bengal as the reducing agent and triacetoxy(methyl)silane and allyloxytrimethylsilane as silicon sources.

Cited by 3 publications

References 55 publications

Construction of a stable fluorescent sensor based on CsPbBr3/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol

Construction of a stable fluorescent sensor based on CsPbBr3/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol

Broad-Spectrum Bactericidal Multifunctional Tiny Silicon-Based Nanoparticles Modified with Tannic Acid for Healing Infected Diabetic Wounds

Indocalamus Leaves Carbon Dots as a Potential Antibacterial Agent

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Construction of a stable fluorescent sensor based on CsPbBr₃/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol

Construction of a stable fluorescent sensor based on CsPbBr₃/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol