The preparation of t‐butyl acrylate, methyl acrylate, and styrene block copolymers by atom transfer radical polymerization: Precursors to amphiphilic and hydrophilic block copolymers and conversion to complex nanostructured materials

Ma, Qinggao; Wooley, Karen L.

doi:10.1002/1099-0518(200012)38:1+<4805::aid-pola180>3.3.co;2-f

Cited by 109 publications

(171 citation statements)

References 0 publications

Supporting

Mentioning

166

Contrasting

Unclassified

Order By: Relevance

“…PI: Synthesis of PAA-b-PMA-b-PS triblock copolymers. The PAA 150 -b-PMA 60 -b-PS 240 used in this study was synthesized by an atom transfer radical polymerization, following previous reported procedure 39 . In brief, t-butyl acrylate (ca.…”

Section: Methodsmentioning

confidence: 99%

Disk-cylinder and disk-sphere nanoparticles via a block copolymer blend solution construction

et al. 2013

Self Cite

View full text Add to dashboard Cite

Researchers strive to produce nanoparticles with complexity in composition and structure. Although traditional spherical, cylindrical and membranous, or planar, nanostructures are ubiquitous, scientists seek more complicated geometries for potential functionality. Here we report the simple solution construction of multigeometry nanoparticles, disk-sphere and diskcylinder, through a straightforward, molecular-level, blending strategy with binary mixtures of block copolymers. The multigeometry nanoparticles contain disk geometry in the core with either spherical patches along the disk periphery in the case of disk-sphere particles or cylindrical edges and handles in the case of the disk-cylinder particles. The portions of different geometry in the same nanoparticles contain different core block chemistry, thus also defining multicompartments in the nanoparticles. Although the block copolymers chosen for the blends are important for the definition of the final hybrid particles, the control of the kinetic pathway of assembly is critical for successful multigeometry particle construction.

show abstract

Section: Methodsmentioning

confidence: 99%

Disk-cylinder and disk-sphere nanoparticles via a block copolymer blend solution construction

et al. 2013

Self Cite

View full text Add to dashboard Cite

show abstract

“…[8][9][10][11][12] Usually in the past, acrylic acid was polymerized by a free radical process, which cannot give rise to low polydispersity samples or to block copolymers. Several attempts have been made to apply CRP to the polymerization of AA without much success.…”

Section: Introductionmentioning

confidence: 99%

“…[14] An alternative method to obtain poly(acrylic acid) with controlled dimensions and narrow polydispersity consists of preparing a precursor that can be chemically modified leading to the poly(acrylic acid). Generally, the precursor used in this way is poly(tert-butyl acrylate) which can be easily hydrolyzed in poly(acrylic acid) by the deprotection reaction with acids (e.g., hydrochloric acid, [15] p-toluenesulfonic acid, [16] methanesulfonic acid, [17] trifluoroacetic acid [10,18,19] ). However, Charleux and co-workers have reported the first direct nitroxide-mediated polymerization of acrylic acid in the presence of SG1 and dioxane as solvent avoiding transfer reaction.…”

Section: Introductionmentioning

confidence: 99%

Self‐Assembly in Water of Poly(acrylic acid)‐Based Diblock Copolymers Synthesized by Nitroxide‐Mediated Polymerization

Laruelle

François

Billon

2004

Macromol. Rapid Commun.

View full text Add to dashboard Cite

Summary: Amphiphilic diblock copolymers consisting of a hydrophilic block, poly(acrylic acid), and a hydrophobic block, polystyrene, were synthesized by direct nitroxide‐mediated polymerization using the PS block as a macro‐initiator for the first time. Several techniques were used to characterize the amphiphilic block copolymers (size exclusion chromatography, NMR spectroscopy). The proposed method can lead to samples with a broad range of composition and molar mass. Preliminary studies of their self‐assembly in aqueous medium using fluorescence spectroscopy and small‐angle neutron scattering are presented.Schematic of the formation of the PS‐b‐PAA block copolymers and their micellization in aqueous media.imageSchematic of the formation of the PS‐b‐PAA block copolymers and their micellization in aqueous media.

show abstract

“…An indirect polymerization method that involved preparation of the PtBA hydrophobic block followed by hydrolysis to form the PAA hydrophilic block (Ma and Wooley, 2000;Strandman et al, 2006;Chen et al, 2008) was chosen to synthesize the amphiphilic block copolymers, PMMAb-PAA. The indirect method avoided some of the disadvantages of the direct polymerization method, e.g., difficulty in choosing solvent because of the presence of both polar and non-polar monomers, poor controllability of the polymer structure, high viscosity when the molecular weight (Mn) of the amphiphilic (co)polymers reached high levels, inaccuracy of characterization because of micelle formation, and possible cleavage of S-C=S bonds from the chain transfer agent under acidic conditions.…”

Section: Discussionmentioning

confidence: 99%

Synthesis of Carboxylic Block Copolymers via Reversible Addition Fragmentation Transfer Polymerization for Tooth Erosion Prevention

et al. 2014

View full text Add to dashboard Cite

Dental professionals are seeing a growing population of patients with visible signs of dental erosion. The approach currently being used to address the problem typically leverages the enamel protection benefits of fluoride. In this report, an alternative new block copolymer with a hydrophilic polyacrylic acid (PAA) block and a hydrophobic poly(methyl methacrylate) (PMMA) block was developed to similarly reduce the mineral loss from enamel under acidic conditions. This series of PMMA-b-PAA block copolymers was synthesized by reversible addition fragmentation transfer (RAFT) polymerization. Their structures were characterized by gel permeation chromatography (GPC) and 1 H nuclear magnetic resonance (NMR) spectra. The molar fractions of acrylic acid (AA) in the final block copolymer were finely controlled from 0.25 to 0.94, and the molecular weight (Mn) of PMMA-b-PAA was controlled from 10 kDa to 90 kDa. The binding capability of the block copolymer with hydroxyapatite (HAP) was investigated by ultravioletvisible spectroscopy (UV-Vis) and Fourier transform infrared (FTIR) spectroscopy. FTIR spectra confirmed that the PMMA-b-PAA block copolymer could bind to HAP via bridging bidentate bonds. Both UV-Vis and FTIR spectra additionally indicated that a high polymer concentration and low solution pH favored the polymer binding to HAP. The erosion-preventing efficacy of the PMMA-b-PAA block copolymer in inhibiting HAP mineral loss was quantitatively evaluated by atomic absorption spectroscopy (AAS). Based on the results, polymer treatment reduced the amount of calcium released by 27% to 30% in comparison with the unprotected samples. Scanning electron microscope (SEM) observations indicated that PMMA-b-PAA polymer treatment protected enamel from acid erosion. This new amphiphilic block copolymer has significant potential to be integrated into dentifrices or mouthrinses as an alternative non-fluoride ingredient to reduce tooth erosion.

show abstract

The preparation of t‐butyl acrylate, methyl acrylate, and styrene block copolymers by atom transfer radical polymerization: Precursors to amphiphilic and hydrophilic block copolymers and conversion to complex nanostructured materials

Cited by 109 publications

References 0 publications

Disk-cylinder and disk-sphere nanoparticles via a block copolymer blend solution construction

Disk-cylinder and disk-sphere nanoparticles via a block copolymer blend solution construction

Self‐Assembly in Water of Poly(acrylic acid)‐Based Diblock Copolymers Synthesized by Nitroxide‐Mediated Polymerization

Synthesis of Carboxylic Block Copolymers via Reversible Addition Fragmentation Transfer Polymerization for Tooth Erosion Prevention

Contact Info

Product

Resources

About