The presence of different growth factors does not influence bone response to hydroxyapatite: preliminary results

Marini, Ettore; Ballanti, P.; Silvestrini, G.; Valdinucci, F.; Bonucci, E.

doi:10.1007/s10195-004-0037-6

Cited by 15 publications

(11 citation statements)

References 96 publications

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“…Although HA nanostructures are used as ceramic-base implants, the available carbonate apatite of the coated surface results in minimum stabilization and fixture of the implants to surround the tissues and, based on the chemical mechanistic features of HA particles, causes the inhibition of cancer cell growth [19][20][21][22][23][24][25][26].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Surface characterization and corrosion behavior of calcium phosphate-base composite layer on titanium and its alloys via plasma electrolytic oxidation: A review paper

Rafieerad

Ashra

Mahmoodian

et al. 2015

Materials Science and Engineering: C

151

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Section: Accepted Manuscriptmentioning

confidence: 99%

Surface characterization and corrosion behavior of calcium phosphate-base composite layer on titanium and its alloys via plasma electrolytic oxidation: A review paper

Rafieerad

Ashra

Mahmoodian

et al. 2015

Materials Science and Engineering: C

151

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“…HAp, which is naturally present in the bone structure, possesses good properties of hardness, biocompatibility, osteoconductivity, some bioactivity, and a high resistance to moisture . HAp can promote new bone ingrowth through an osteoconduction mechanism without causing local or systemic toxicity, inflammation, or a foreign body response . HAp has been explored as a bioactive scaffold material used in guided bone regeneration .…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Hydroxyapatite Using Ammonium Hydroxide and Ethylenediaminetetraacetic Acid

Park

Kim

Choi³

et al. 2015

Bulletin Korean Chem Soc

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“…The formation of connective tissue fibers (2-3 weeks), which make a fiber mesh containing carbonated apatite, is one such response that occurs initially [76,77]. This tissue-free layer develops onto the ceramic surface and actively contributes both to a strong fixation of the implant to the surrounding bone tissues and to the acceleration of bone integration and healing at early implantation times [78][79][80][81]. These aspects are of key-importance for any implant system [82].…”

Section: In Vivo Assessment Of Pld Cap-based Coatingsmentioning

confidence: 99%

In Vivo Assessment of Synthetic and Biological-Derived Calcium Phosphate-Based Coatings Fabricated by Pulsed Laser Deposition: A Review

Duta

2021

Coatings

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The aim of this review is to present the state-of-the art achievements reported in the last two decades in the field of pulsed laser deposition (PLD) of biocompatible calcium phosphate (CaP)-based coatings for medical implants, with an emphasis on their in vivo biological performances. There are studies in the dedicated literature on the in vivo testing of CaP-based coatings (especially hydroxyapatite, HA) synthesized by many physical vapor deposition methods, but only a few of them addressed the PLD technique. Therefore, a brief description of the PLD technique, along with some information on the currently used substrates for the synthesis of CaP-based structures, and a short presentation of the advantages of using various animal and human implant models will be provided. For an in-depth in vivo assessment of both synthetic and biological-derived CaP-based PLD coatings, a special attention will be dedicated to the results obtained by standardized and micro-radiographies, (micro) computed tomography and histomorphometry, tomodensitometry, histology, scanning and transmission electron microscopies, and mechanical testing. One main specific result of the in vivo analyzed studies is related to the demonstrated superior osseointegration characteristics of the metallic (generally Ti) implants functionalized with CaP-based coatings when compared to simple (control) Ti ones, which are considered as the “gold standard” for implantological applications. Thus, all such important in vivo outcomes were gathered, compiled and thoroughly discussed both to clearly understand the current status of this research domain, and to be able to advance perspectives of these synthetic and biological-derived CaP coatings for future clinical applications.

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The presence of different growth factors does not influence bone response to hydroxyapatite: preliminary results

Cited by 15 publications

References 96 publications

Surface characterization and corrosion behavior of calcium phosphate-base composite layer on titanium and its alloys via plasma electrolytic oxidation: A review paper

Surface characterization and corrosion behavior of calcium phosphate-base composite layer on titanium and its alloys via plasma electrolytic oxidation: A review paper

Synthesis and Characterization of Hydroxyapatite Using Ammonium Hydroxide and Ethylenediaminetetraacetic Acid

In Vivo Assessment of Synthetic and Biological-Derived Calcium Phosphate-Based Coatings Fabricated by Pulsed Laser Deposition: A Review

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