Infant powdered milk (i.e., infant formula) is a rich and convenient source of nutrients, substituting for human breast milk in many countries. Moreover, it is the basic foodstuff for the infants because of its minerals and proteins, which are essential for their growth and development. However, there are still limited data on radioactivity levels in infant powdered milk around the world, including Malaysia, for radiological health risk assessment. Thus, it is very important to assess the radioactivity levels and the associated dose in the widely consumed powered infant milk. As a result, activity concentrations of 226 Ra, 232 Th, 40 K, and 137 Cs were determined in only 14 brands of powdered milk consumed by Malaysian infants, which are imported from various regions around the world for a cross-sectional survey. The obtained mean activities of 226 Ra, 232 Th, 40 K, and 137 Cs are 3.05 -1.84, 2.55 -2.48, 99.1 -69.5, and 0.27 -0.19 Bq/kg, respectively. Among the analyzed milk samples, the brand from Philippines (Lactogen) showed low level of radioactivity, while a Singaporean brand (S26 SMA Gold) showed the highest. The artificial radionuclide, 137 Cs, is virtually not detected in most of the investigated brands. The estimated mean annual effective doses due to the consumption of powdered milk are 635.13 and 111.45 lSv/year for infants £1 year and infants 1-2 years old, respectively. The obtained dose value is significantly higher (in case of infants £1 year old) and lower (in case of infants 1-2 years old) compared with the UNSCEAR reported value (290 lSv/year) for the general population. In general, values are lower than the FAO/WHO and ICRP recommended limit of 1.0 mSv/year for all ages.