The Presence of Patent Foramen Ovale in the Superior Type of Sinus Venosus Atrial Septal Defect

Samiei, Niloufar; Akiash, Nehzat; Naeini, Sepideh Jafari; Nikpajouh, Akbar; Pazoki, Mahboubeh

doi:10.18502/jthc.v15i3.4218

Cited by 3 publications

(2 citation statements)

References 31 publications

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“…Despite the unclear association between PFO and SV-ASD, PFO often accompanies SV-ASD and may be missed before and during the operation. 10 Our study recorded a PFO rate of 45.5% (Table 1).…”

Section: Discussionmentioning

confidence: 61%

Totally Endoscopic Surgery for Repairing Sinus Venosus Atrial Septal Defect Using Double-Patch Technique on Beating Heart

Dang¹,

Nguyen³

2023

Innovations�(Phila)

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Objective: Minimally invasive cardiac surgery has not been widely applied in repairing sinus venosus atrial septal defect (SV-ASD). Most were minithoracotomy using the single-patch technique for patients with anomalous pulmonary veins (APVs) connecting to the superior vena cava–right atrium (SVC-RA) junction. It is unclear whether patients with APVs draining high to the SVC can be repaired safely and effectively through port access. Methods: From May 2019 to October 2022, 11 consecutive SV-ASD patients with APVs connecting high to the SVC were enrolled in this prospective study. One 12 mm port and 2 trocars (5.5 mm and 10 mm) were established. The pleural and pericardial spaces were filled with CO2. The SVC was snared just below the azygos vein. The RA incision was longitudinally extended along the SVC-RA junction to the SVC. The bovine pericardial patches were used to redirect the APV flow to the left atrium through the ASD and to enlarge the SVC and the SVC-RA junction. Results: There were no early or late deaths and no reoperations. The concomitant procedures included 5 patients (45.5%) with patent foramen ovale closure, 2 with ASD extension, and 3 with tricuspid valve repair. No endoscopic failure was recorded. The average cardiopulmonary bypass and operative times were 96 (23) min and 190 (30) min, respectively. No cases of venous stenosis or sinus node dysfunction were noted during follow-up of 16.4 ± 12.2 months. Conclusions: SV-ASD with the APVs draining high to the SVC could be repaired safely and effectively through port access with a double-patch technique.

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Section: Discussionmentioning

confidence: 61%

Totally Endoscopic Surgery for Repairing Sinus Venosus Atrial Septal Defect Using Double-Patch Technique on Beating Heart

Dang¹,

Nguyen³

2023

Innovations�(Phila)

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“…Sinus venosus-type atrial septal defect (ASD) represents approximately 4% to 11% of all ASDs and may be associated with other cardiac anomalies, such as anomalous pulmonary venous connection and patent foramen ovale (PFO). 1 The foramen ovale is an interatrial communication that functionally closes after birth, when left atrial pressure exceeds right atrial pressure. A flap defect results from failure of fusion of primum and secundum atrial septa, usually providing an intermittent communication.…”

mentioning

confidence: 99%

Unrecognized Patent Foramen Ovale in Patient With Sinus Venosus-Type Atrial Septal Defect With Partial Anomalous Pulmonary Venous Return

Capone

Brown²,

Mukherji³

2023

A&A Practice

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ASA = atrial septal aneurysm; ASD = atrial septal defect; CFD = color flow Doppler; CPB = cardiopulmonary bypass; CT = computed tomography; HIPAA = Health Insurance Portability and Accountability Act; LV = left ventricular; PAPVR = partial anomalous pulmonary venous return; PFO = patent foramen ovale; RUPV = right upper pulmonary vein; SVASD = sinus venosus-type atrial septal defect; SVC = superior vena cava; TEE = transesophageal echocardiogram; TTE = transthoracic examination Sinus venosus-type atrial septal defect (ASD) represents approximately 4% to 11% of all ASDs and may be associated with other cardiac anomalies, such as anomalous pulmonary venous connection and patent foramen ovale (PFO). 1 The foramen ovale is an interatrial communication that functionally closes after birth, when left atrial pressure exceeds right atrial pressure. A flap defect results from failure of fusion of primum and secundum atrial septa, usually providing an intermittent communication. It is usually a benign finding and affects between 20% and 34% of the adult population. 2 We describe a patient scheduled for repair of a large superior-type sinus venosis-type ASD (SVASD). Intraoperative transesophageal echocardiogram (TEE) before repair did not reveal the presence of a PFO. However, soon after successful patch repair of the ASD, a large PFO was noticeable on TEE examination, necessitating reexploration and repair of the PFO. The clinical implications of an unrecognized PFO are consequential, as it can lead to recurrent embolization. Written Health Insurance Portability and Accountability Act (HIPAA) authorization was obtained from the patient for publication.

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Exosomes: Potential Player in Endothelial Dysfunction in Cardiovascular Disease

et al. 2021

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Exosomes are spherical bilayer membrane vesicles with an average diameter of 40–100 nm. These particles perform a wide range of biological activities due to their contents, including proteins, nucleic acids, lipids, lncRNA, and miRNA. Exosomes are involved in inflammation induction, oxidative stress and apoptosis, which can be effective in endothelial dysfunction. Due to the induction of mentioned processes in the endothelial cells, the intercellular connections are destroyed, cell permeability increases and finally cell efficiency decreases and functional defects occur. Cardiovascular disease (CVDs) are of consequences of endothelial dysfunction. Thus by identifying the exosome signaling pathways, which induce inflammation, oxidative stress, and apoptosis, endothelial dysfunction and subsequently CVDs can be reduced; exosomes can be used for appropriate target therapy.

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The Presence of Patent Foramen Ovale in the Superior Type of Sinus Venosus Atrial Septal Defect

Cited by 3 publications

References 31 publications

Totally Endoscopic Surgery for Repairing Sinus Venosus Atrial Septal Defect Using Double-Patch Technique on Beating Heart

Totally Endoscopic Surgery for Repairing Sinus Venosus Atrial Septal Defect Using Double-Patch Technique on Beating Heart

Unrecognized Patent Foramen Ovale in Patient With Sinus Venosus-Type Atrial Septal Defect With Partial Anomalous Pulmonary Venous Return

Exosomes: Potential Player in Endothelial Dysfunction in Cardiovascular Disease

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