The Present and Future Burden of Contact Dermatitis from Acrylates in Manicure

Gatica‐Ortega, María‐Elena; Pastor‐Nieto, María‐Antonia

doi:10.1007/s40521-020-00272-w

Cited by 8 publications

(24 citation statements)

References 78 publications

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“…Note: Adapted from Gatica-Ortega ME. 39 recommendations to minimize the exposure of the mucosae to acrylate monomers during the dental procedure (Table 3).…”

Section: Remind Your Doctors Of Your Acrylate's Allergy In Case Medicalmentioning

confidence: 99%

Prognosis and sequelae of meth(acrylate) sensitization in beauticians and consumers of manicure materials

Gatica‐Ortega,

Rodríguez‐Lago,

Beneyto

et al. 2023

Contact Dermatitis

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BackgroundAllergic contact dermatitis from (meth)acrylic monomers (ACDMA) in manicure products is increasing.ObjectiveTo evaluate the prognosis, work performance impairment and sequelae of a cohort of beauticians and manicure consumers with ACDMA sensitized from the exposure to manicure products.MethodsWe conducted a telephone survey with patients diagnosed with ACDMA.ResultsOne hundred and six patients were evaluated, including 75 (70.8%) beauticians and 31 (29.2%) consumers. All were women with a mean age of 39 (19–62). Thirty‐seven of 75 beauticians (49.3%) continued to work. Twenty‐seven of 106 (25.5%) patients continued to use manicure products with (meth)acrylates regularly. Seventeen of 51 (33.3%) patients who discontinued the exposure described ongoing nail/periungual changes. Nine of 58 (15.5%) patients who required dental restoration, orthodontic or occlusal splint materials recalled reactions from them; and, 25 of 96 (26%) who used sanitary napkins recalled intolerance to them starting after the diagnosis of ACDMA. Fifteen of 25 (60%) discontinued the use of sanitary napkins.Conclusion49.3% beauticians continued to work; most patients stopped wearing acrylic manicure materials; reactions from dental materials were not uncommon, however, removal of dental materials was never required; and, reactions to sanitary napkins developing after the diagnosis of ACDMA were common most leading to discontinuation of use.

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“…Note: Adapted from Gatica-Ortega ME. 39 recommendations to minimize the exposure of the mucosae to acrylate monomers during the dental procedure (Table 3).…”

Section: Remind Your Doctors Of Your Acrylate's Allergy In Case Medicalmentioning

confidence: 99%

Prognosis and sequelae of meth(acrylate) sensitization in beauticians and consumers of manicure materials

Gatica‐Ortega,

Rodríguez‐Lago,

Beneyto

et al. 2023

Contact Dermatitis

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“…In the ingredients list of the product, MMA and EGDMA were declared as polymerised, whereas HEMA, a marker allergen for contact allergy to methacrylates, was not declared. As ECA does not cross‐react with methacrylates, 11 we suspect that the patient was sensitised to residual monomers contained in the nail glue. In a random sample of nine nail glues sold within the European Union, Symanzik et al 1 found that all glues contained ECA and poly MMA.…”

Section: Discussionmentioning

confidence: 99%

The bitter side of nail art: A teenage girl's encounter with (meth)acrylate‐induced allergic contact dermatitis from nail glue

Quaade

Simonsen

2023

Contact Dermatitis

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“…It is often troublesome to identify the source of exposure to (meth)acrylates in industrial, medical or other consumer products (e.g., inks, glues, sanitary napkins, medical devices, etc.) because information regarding their composition and cooperation of manufacturers is usually deficient 24–26 . Some patients were exposed to (meth)acrylates in dental materials 24 including a dentist and a dental prosthetist who were occupationally exposed to (meth)acrylates at their workplaces; a dental assistant and consumer of acrylic manicure products who developed airborne reactions and systemic symptoms; one patient diagnosed with burning mouth syndrome who experienced worsening of her symptoms after using a denture adhesive with acrylates; one patient with night oral soreness for 2 years which she related to new dental covers and one patient with reactions from a removable denture who improved with avoidance measures.…”

Section: Discussionmentioning

confidence: 99%

2‐Hydroxyethyl methacrylate (2‐HEMA) sensitization, a global epidemic at its peak in Spain?

Gatica‐Ortega,

Pastor‐Nieto,

Giménez‐Arnau

et al. 2024

Contact Dermatitis

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BackgroundA global epidemic of allergic contact dermatitis to (meth)acrylates has been described in relation to the widespread use of manicure products.ObjectivesTo evaluate the frequency of sensitization to 2‐hydroxyethyl methacrylate (2‐HEMA) among consecutively patch tested patients with eczema in Spain; the percentage of current relevance; the MOAHLFA index; and, the potential sources of exposure to (meth)acrylates.MethodsFrom January 2019 to December 2022, 2‐HEMA 2% pet. was prospectively patch tested in 24 REIDAC (Spanish Allergic Contact Dermatitis Registry) centres.ResultsSix thousand one hundred thirty‐four patients were consecutively patch tested with 2‐HEMA 2% pet. 265/6134 (4.3%) were positive. Positive reactions of current relevance were identified to involve 184/265 (69%). The efficiency (number of patch tests needed to detect relevant positive patch test reactions) was 34 (6134/184). The variable ‘occupational’ was found to be significantly associated with a higher risk for relevant positive reactions to 2‐HEMA (OR: 10.9; 95% CI: 8.1–14.9).Conclusion(Meth)acrylate sensitization is a prevalent health issue in Spain. 2‐HEMA 2% pet. has been identified to be a highly effective (meth)acrylate allergy marker in the GEIDAC baseline series. The responsible authorities should implement policies guaranteeing accurate labelling of industrial, medical, and consumer materials while ensuring the enforcement of said labelling through appropriate legal means.

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The Present and Future Burden of Contact Dermatitis from Acrylates in Manicure

Cited by 8 publications

References 78 publications

Prognosis and sequelae of meth(acrylate) sensitization in beauticians and consumers of manicure materials

Prognosis and sequelae of meth(acrylate) sensitization in beauticians and consumers of manicure materials

The bitter side of nail art: A teenage girl's encounter with (meth)acrylate‐induced allergic contact dermatitis from nail glue

2‐Hydroxyethyl methacrylate (2‐HEMA) sensitization, a global epidemic at its peak in Spain?

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