S U M M A R YSix marine bacteria which synthesize macromolecular antibiotics were isolated from neritic waters on the French Mediterranean coast, and their frequency recorded over two successive years.They appeared in relatively large numbers during the period August to December, and can be identified as marine pseudomonads; however, the low guaninecytosine ratio of their DNA, lack of catalase and specific self-inhibition are not compatible with the characteristics of the genus Pseudomonas. Two produced violacein, usually synthesized by bacteria belonging to the genus Chromobacterium. Their taxonomic position is discussed.
I N T R O D U C T I O NMany marine bacteria release antibacterial substances into culture media. These substances inhibit various terrestrial and in particular Gram-positive bacteria. , 1971) and the Baltic Sea (Bonde, 1968). They have been isolated from most marine biotopes, including surface or deep waters, immersed substrates, surface of seaweeds, and fine or rough sediments, and have been identified as species of Bacillus, Micrococcus, Pseudomonas, Vibrio, Flavobacterium, Alcaligenes, Xanthomonas and Achromobacter.Bacteria isolated from reasonably unpolluted Mediterranean coastal waters near Nice are characterized by the macromolecular and polysaccharide nature of their antibacterial substance and by the mechanism of their inhibition of terrestrial bacteria, mainly Gram-positive species but also a few Gram-negative ones such as Klebsiella spp. and Escherichiu spp. (Gauthier, 1970). Seasonal variations in the numbers of such bacteria within neritic heterotrophic bacterial populations over two successive years (1969-1 970) are reported, together with their morphological, physiological and biochemical characters.