The Preterm Prediction study: Association between maternal body mass index and spontaneous and indicated preterm birth

Hendler, Israel; Goldenberg, Robert L.; Mercer, Brian M.; Iams, Jay D.; Meis, Paul J.; Moawad, Atef H.; MacPherson, Cora; Caritis, Steve N.; Miodovnik, Menachem; Menard, Kate; Thurnau, Gary R.; Sorokin, Yoram

doi:10.1016/j.ajog.2004.09.021

Cited by 278 publications

(234 citation statements)

References 26 publications

Supporting

Mentioning

208

Contrasting

Unclassified

Order By: Relevance

“…The need for induction of labour and caesarean deliveries when the mother is obese or morbidly obese has been reported by numerous studies. 5,[11][12][13][14][15][16][17][18][19] Vahratian et al 20 discuss the need for more frequent administration of oxytocin to stimulate contractions during labour and a significant increase in emergency caesarean deliveries in the obese mother. Rode et al 21 also address a significant increase in emergency caesarean delivery rates, as well as overall caesarean rates, and elective caesareans.…”

Section: Discussionmentioning

confidence: 99%

Obesity in pregnancy: a study of the impact of maternal obesity on NHS maternity services

Heslehurst

Lang

Rankin

et al. 2007

BJOG

139

133

View full text Add to dashboard Cite

Objective To gain a detailed understanding of healthcare professionals' perceptions of the impact that caring for obese pregnant women has on maternity services.Design Qualitative interview study using purposeful sampling and face-to-face interviews.Setting Sixteen maternity units in NHS Trusts in the North East Government Office Region of England, UK.Sample Thirty-three maternity and obstetric healthcare professionals with personal experience of managing the care of obese pregnant women.Methods Semi-structured interviews with healthcare professionals representing each maternity unit in the region. Transcripts were analysed using systematic content analysis.Main outcome measures Views on the impact maternal obesity has on maternity services, the facilities required to care for obese mothers in pregnancy, and existing services directed towards maternal obesity.Results Five dominant themes relating to service delivery emerged; booking appointments, equipment, care requirements, complications and restrictions, and current and future management of care. Many of the issues identified were associated with managing the care of obese women in pregnancy safely, resources and cost issues to be able to do this, multidisciplinary care requirements because of coexisting morbidities when the mother is obese, and restricted care options and patient choice.Conclusions Healthcare professionals in the North East of England feel that maternal obesity has a major impact on services and resource, on the health of both the mother and child, and on the psychological wellbeing of the mother.

show abstract

Section: Discussionmentioning

confidence: 99%

Obesity in pregnancy: a study of the impact of maternal obesity on NHS maternity services

Heslehurst

Lang

Rankin

et al. 2007

BJOG

139

133

View full text Add to dashboard Cite

show abstract

“…In LMICs, IUGR and preterm delivery share several common determinants such as low body mass index, malaria, smoking, pregnancy-induced hypertension, and pre-eclampsia. 25,29,51,65 Thus, countries with high prevalence of risk factors (such as low maternal body mass index and malaria) with a resulting high prevalence of term LBW are also more likely to present high rates of preterm LBW births. In addition, a number of studies 7,23,28,45,50 show that preterm births are more frequent among poor populations.…”

Section: Discussionmentioning

confidence: 99%

How many low birthweight babies in low- and middle-income countries are preterm?

Barros

Villar

et al. 2011

Rev. Saúde Pública

View full text Add to dashboard Cite

OBJECTIVE:To assess the prevalence of preterm birth among low birthweight babies in low and middle-income countries. METHODS:Major databases (PubMed, LILACS, Google Scholar) were searched for studies on the prevalence of term and preterm LBW babies with fi eld work carried out after 1990 in low-and middle-income countries. Regression methods were used to model this proportion according to LBW prevalence levels. RESULTS:According to 47 studies from 27 low-and middle-income countries, approximately half of all LBW babies are preterm rather than one in three as assumed in studies previous to the 1990s. CONCLUSIONS:The estimate of a substantially higher number of LBW preterm babies has important policy implications in view of special health care needs of these infants. As for earlier projections, our fi ndings are limited by the relative lack of population-based studies.

show abstract

“…Prior studies have shown that obesity is protective against spontaneous preterm birth, 4,5 though there may be a specific relationship between obesity and early preterm premature rupture of membranes. 7 However, no studies have examined outcomes in the obese patient with CI and cerclage placement.…”

Section: Discussionmentioning

confidence: 99%

“…2,3 Past studies have demonstrated that obesity is protective against spontaneous preterm delivery. 4,5 However, it has been shown to be a significant risk factor for indicated preterm delivery. [5][6][7] Recent data indicate that preterm premature rupture of membranes is significantly increased in women with a body mass index (BMI) >30 kg m À2 .…”

Section: Introductionmentioning

confidence: 99%

Does increasing body mass index affect cerclage efficacy?

et al. 2012

View full text Add to dashboard Cite

Objective: To study the relationship between body mass index (BMI) and gestational age (GA) at delivery in patients with cervical insufficiency (CI) undergoing cerclage.Study Design: We accessed a database of patients with singleton gestations undergoing cerclage (N ¼ 168) for a well-characterized history of CI, shortened cervix <2.5 cm with a history of prior preterm delivery or prolapse of membranes through the external os. Univariate and multivariate logistic regression analysis were performed to compare obstetrical outcomes between obese and normal-weight patients.Result: Prior preterm delivery <35 weeks in obese vs normal-weight patients was significantly higher (44% vs 9%), odds ratio ¼ 6.9 (95% CI: 2.5, 18.5), with lower mean GA at delivery (32.6 ± 7.0 vs 37.2 ± 3.4 weeks, P<0.001). After controlling for confounders, BMI remained significantly predictive of prematurity (coefficient: À0.12, adjusted R 2 ¼ 0.24), such that every additional 1 unit of BMI was associated with a 1-day reduction in GA at delivery (P ¼ 0.03).Conclusion: An inverse correlation exists between BMI and GA at delivery in patients with CI receiving cerclage. The findings are unexpected given the protective effect of obesity on spontaneous preterm delivery.

show abstract

The Preterm Prediction study: Association between maternal body mass index and spontaneous and indicated preterm birth

Abstract: Obesity before pregnancy is associated with a lower rate of spontaneous preterm birth.

Cited by 278 publications

References 26 publications

Obesity in pregnancy: a study of the impact of maternal obesity on NHS maternity services

Obesity in pregnancy: a study of the impact of maternal obesity on NHS maternity services

How many low birthweight babies in low- and middle-income countries are preterm?

Does increasing body mass index affect cerclage efficacy?

Contact Info

Product

Resources

About