The Prevalence and Characteristics of Patients Diagnosed with Osteogenesis Imperfecta at the Zambia Italian Orthopedics Hospital Community Based Rehabilitation Project

Kabengo, Stella; Munalula-Nkandu, Esther; Munthali, James; Nkhata, Loveness A.; Shula, Hastings

doi:10.11648/j.sjph.20150305.40

Cited by 2 publications

(3 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mean age of the present study was 6.96 years. A study from Kabengo et al found that most of the patients diagnosed with OI were under 10 years old [21]. Type III OI was the most common type in this study.…”

Section: During Thesupporting

confidence: 52%

See 1 more Smart Citation

Determinant Factors of the Quality of Life in Children with Osteogenesis Imperfecta during the COVID-19 Pandemic

Rochmah

Mustikasari²,

Faizi³

et al. 2022

Open Access Maced J Med Sci

View full text Add to dashboard Cite

Background: Osteogenesis imperfecta (OI) is a common chronic illness with increasing prevalence. Coronavirus disease 2019 (COVID-19) and large society restriction policies in Indonesia cause problems and might affect the quality of life (QoL) of children with OI. Objective: To evaluate determinant factors that affect OI children's QoL pre and during the first year of the COVID-19 pandemic. Method: This was a cross-sectional study design conducted in the Pediatric Endocrinology Outpatient Clinic, Dr. Soetomo Hospital, Surabaya, Indonesia, during the COVID-19 pandemic in 2020 to assess the patient’s QoL. This study used a diagnostic group with questionnaires. The instrument included the Pediatric Quality of Life Inventory 4.0 Generic Score, a standardized interview questionnaire comprising questions on the participant characteristics and determinant factors pre and during the COVID-19 pandemic. Analysis of determinant factors pre and during the pandemic used McNemar. Correlation between determinant factors and QoL used linear regression for physical and emotional dimensions and logistic regression for social, school, and total score. Result: Of the 22 children with OI, 19 had fear of visiting the hospital (p < 0.001), and 16 had obstacles to visiting the hospital (p < 0.01). The determinant factors for taking calcium and/or vitamin D supplementation pre and during the COVID-19 pandemic affected school functioning (p = 0.015) and the total score (p = 0.027). Conclusion: The significant risk factors pre and during COVID-19 were fear of and obstacles to visiting the hospital. Supplementation of calcium and/or vitamin D pre and during the COVID-19 pandemic significantly impacted school functioning and the total score.

show abstract

Section: During Thesupporting

confidence: 52%

“…Similarly, Newacheck stated that there was no difference in gender preference in children with OI [20]. In contrast, Kabengo et al found that female prevalence was more profound than male [21]. The mean age of the present study was 6.96 years.…”

Section: During Thecontrasting

confidence: 43%

Determinant Factors of the Quality of Life in Children with Osteogenesis Imperfecta during the COVID-19 Pandemic

Rochmah

Mustikasari²,

Faizi³

et al. 2022

Open Access Maced J Med Sci

View full text Add to dashboard Cite

show abstract

“…In the past year, the mean number of fractures was 2.50 (SD 6.51) times, with the femur being the most common fracture site in 17 children with OI [21].…”

Section: Discussionmentioning

confidence: 99%

Quality of Life among Children with Osteogenesis Imperfecta Receiving Bisphosphonate Therapy Before and during the 1st Year of the COVID-19 Pandemic in Dr. Soetomo Hospital, Surabaya

Mustikasari

Rochmah

Faizi

et al. 2023

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND: Osteogenesis imperfecta (OI) is a chronic illness caused by a connective tissue disorder that may lead to frequent fractures. Therefore, it may influence the quality of life (QoL). The study on QoL among children with OI during the coronavirus disease-19 (COVID-19) pandemic is still limited. AIM: This study aims to evaluate QoL before and during the COVID-19 pandemic in children with OI. METHODS: This cross-sectional study took place in the Pediatric Endocrinology Outpatient Clinic at Dr. Soetomo General Hospital, Surabaya, in 2020. The pre-pandemic data came from 2019 medical records. The questionnaire used was the Pediatric Quality of Life Inventory (PedsQL) 4.0 generic core. Twenty-two patients joined the study; 11/22 of them were girls. RESULTS: The mean age, fracture, and frequency of zoledronic acid treatment were 6.9 years old, 2.5×/year, and 7.1×/year, respectively. The PedsQL comparisons before and during the first year of the COVID-19 pandemic in each dimension were: Physical (49.57 vs. 42.76; p = 0.001), emotional (63.41 vs. 54.54; p = 0.001), social (58.86 vs. 53.86; p = 0.015), and school functioning (66.13 vs. 56.74; p = 0.001), respectively. The most affected dimension was school functioning (mean difference (minimum–maximum): (−9.39) (−14.28–[−4.49]), whereas the physical, emotional, and social functioning were 6.81 (3.43–10.19), 8.86 (5.06–12.67), and −5.00 (−8.93–(−1.07)), respectively. CONCLUSION: The QoL in children with OI during the COVID-19 pandemic was worst, especially in the school functioning dimension. Online consultation options may be beneficial to improving the QoL.

show abstract

The Prevalence and Characteristics of Patients Diagnosed with Osteogenesis Imperfecta at the Zambia Italian Orthopedics Hospital Community Based Rehabilitation Project

Cited by 2 publications

References 15 publications

Determinant Factors of the Quality of Life in Children with Osteogenesis Imperfecta during the COVID-19 Pandemic

Determinant Factors of the Quality of Life in Children with Osteogenesis Imperfecta during the COVID-19 Pandemic

Quality of Life among Children with Osteogenesis Imperfecta Receiving Bisphosphonate Therapy Before and during the 1st Year of the COVID-19 Pandemic in Dr. Soetomo Hospital, Surabaya

Contact Info

Product

Resources

About