The prevalence and clinico-haematological changes of protozoan diseases in food animals in Alabata, Abeokuta

Biobaku, KT; Takeet, MI; Olurode, SA; Oyewusi, IK; Oni, OO; Oloye, AA

doi:10.4314/njpar.v31i1.69450

Cited by 6 publications

(3 citation statements)

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“…The consequence of this is that the proportion of feed that would be used for growth is reduced as it is metabolized to provide extra energy for maintenance, hence greater growth retardation (Verstegen et al, 1991). Phytochemical screening of the herbs revealed that it is rich in flavonoids and terpenes and the pharmacological actions inherent are believed to be due to the presence of these phytochemicals (Ajagbonna et al, 2003;Biobaku et al, 2009Biobaku et al, , 2010.…”

Section: Discussionmentioning

confidence: 99%

Fractions of Lawsonia inermis Linn leaves reversed the damage caused to major organs involved in diabetic complications by improving their histomorphological appearance in diabetic Wistar rat model

2022

JoSVAS

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Diabetes mellitus (DM) is clinically known as diverse sets of biochemical syndromes with a basic symptom of glucose intolerance and is a major cause of morbidity and mortality worldwide. Diabetes mellitus exclusively disrupts glucose metabolism in various tissues and organs leading to complications such as retinopathy, nephropathy and brain micro-infarcts. This study investigated the positive modulatory effect of Lawsonia inermis Linn leaves on major organs involved in diabetic complications in Wister rats experimentally induced by type 1 diabetes using streptozocine. Lawsonia inermis leaves were partitioned using N-hexane, ethyl acetate and methanol. Fractions obtained were assessed for their modulatory potential. Seven groups of diabetic rats (n=5) were orally administered 100mg/kg of each of the three partitioned fractions, metformin (500mg/kg), glibenclamide (5mg/kg), while untreated hyperglycaemic and normoglycaemic rats received distilled water (ad libitum) daily for 28 days. Mean relative organ weight of the brain, heart, kidney, pancreas and liver increased significantly (p<0.05) in untreated diabetic rats when compared to Lawsonia inermis treated rats and non-diabetic control. Diabetic treated rats showed non-significant (p>0.05) increased weight in all the organs except the pancreas that decreased non-significantly when compared to normoglycemic rats. The histopathology results showed that Lawsonia inermis improved the organ damage seen in diabetic complications through prevention of organomegaly and improvement in histoarchitectural appearance that is devoid of lesions when compared to untreated diabetic control with various lesions. Conclusively, Lawsonia inermis Linn leaves improve significant reduction in organ damage during course of Type 1 diabetes mellitus.

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Section: Discussionmentioning

confidence: 99%

Fractions of Lawsonia inermis Linn leaves reversed the damage caused to major organs involved in diabetic complications by improving their histomorphological appearance in diabetic Wistar rat model

2022

JoSVAS

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“…Protozoal infections are common in tropical and subtropical countries where sanitary conditions, hygiene practices, and control of the vectors of transmission are inadequate. Two types of infections caused by the major types of protozoa of veterinary importance are the haemoparasitic such as Trypanosoma, Babesia, and eileria and the common enteric Coccidia, Toxoplasma, and Giardia [2]. Among protozoan diseases caused by trypanosomes, dourine which is restricted to the Arsi-Bale Zone of Ethiopian highland areas has been recognized by local farmers for many years as "Lappessa" and found to be a threat to the life and productivity of the equine population [3].…”

Section: Introductionmentioning

confidence: 99%

Antiprotozoal Drug Handling and Management Practices in Asella District, Central Oromia, Ethiopia

Ababu¹,

Endashaw²,

Fesseha

et al. 2021

Veterinary Medicine International

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Background and Methods. Protozoal infections such as dourine caused by trypanosomes are found to be a threat to the life and productivity of the equine population. Inappropriate drug use is a problem of the whole world; however, the degree of the problem is higher in developing countries like Ethiopia. Data on handling and management practices of antiprotozoal drugs are not in place; thus, we estimate the handling and management practice via a simple cross-sectional study design in randomly selected veterinary clinics and private pharmacies in and around Asella, Oromia, central Ethiopia. Results. The preliminary survey comprising 70 animal health professionals and animal owners was undertaken through observation, interview using a structured questionnaire, and discussion with key informants to evaluate their handling and management practices of antiprotozoal drugs. According to the finding of this preliminary survey, there was inadequate antiprotozoal drug distribution and only few drugs, namely, diminazene diaceturate, amprolium, and sulfa drugs, were available with different trade names being imported from different manufacturing countries. Among the current available antiprotozoal drugs circulating in the area, those manufactured and imported from China were highly distributed in the majority of veterinary drug shops. The assessment showed that there was a gap in achieving the required knowledge and practice of proper handling and management issues in the professionals and awareness problems in the community. The study indicated that there were inappropriate transportation and storage practices. Moreover, selling drugs without prescription, ignoring farmers without properly informing the drug withdrawal period, and administration of drugs by nonprofessionals were the other most critical and unethical practices in the area. It is emphasized that this inappropriate handling and management practice, scarcity of antiprotozoal drugs, easy accessibility, and distribution by nonprofessionals could potentially affect the quality, safety, and effectiveness of antiprotozoal drugs which may lead to drug resistance development. Conclusion. Hence, continuous awareness creation in the community, capacity building, training, and upgrading programs to the professionals, as well as strict enforcement of drug control and administration regulation of the country, are essential in the overall effort of improving animal health and productivity through the control of protozoan diseases in and around Asella.

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“…Protozoal infections are common in tropical and subtropical countries where sanitary conditions, hygiene practices, and control of the vectors of transmission are inadequate. Two types of infections caused by the major types of protozoa of veterinary importance are the haemoparasitic such as Trypanosome, Babesia, Theileria, and the common enteric Coccidian, Toxoplasma, and Giardia [2]. Among protozoan diseases caused by trypanosomes, dourine which is restricted to the Arsi-Bale zone of Ethiopian highland areas has been recognized by local farmers for many years as 'Lappessa' and found to be a threat to the life and productivity of the equine population [3].…”

Section: Introductionmentioning

confidence: 99%

Antiprotozoal Drugs Handling and Management Practices in Asella District, Central Oromia, Ethiopia

Tilahun¹,

Endashaw²,

Fesseha

2020

Preprint

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Background: Protozoal infections such as Dourine caused by trypanosomes are found to be a threat to the life and productivity of the equine population. Inappropriate drug use is a problem of the whole world; however, the degree of the problem is higher in developing countries like Ethiopia. Data on handling and management practices of antiprotozoal drugs are not in place, thus; we estimate the handling and management practice via a simple cross-sectional study design in randomly selected veterinary clinics, and private pharmacies in and around Asella Oromia, central EthiopiaResults: The preliminary survey comprising 70 animal health professionals and animal owners was undertaken through observation, interview using a structured questionnaire, and discussion with key informants to evaluate their handling and management practices of antiprotozoal drugs. According to the finding of this preliminary survey, inadequate antiprotozoal drug distribution and only a few drugs namely; Diminazine diacetate, Amprolium, and sulfa drugs were available with different trade names being imported from different manufacturing countries. Among the current available antiprotozoal drugs circulating in the area, those manufactured and imported from China were highly distributed in the majority of veterinary drug shops. The assessment showed that there was a gap in achieving the required knowledge and practice of proper handling and management issues in the professionals and awareness problems in the community. The study indicated that there were inappropriate transportation and storage practices. Moreover, selling drugs without prescription, ignoring farmers without properly informing the drug withdrawal period and administration of drugs by nonprofessionals were the other most critical and unethical practices in the area. It is emphasized that this inappropriate handling and management practice, scarcity of antiprotozoal drugs, easy accessibility, and distribution by nonprofessionals could potentially affect the quality, safety, and effectiveness of antiprotozoal drugs which may lead to drug resistance development. Conclusion: Hence, continuous awareness creation in the community, capacity building, training, and upgrading programs to the professionals as well as strict enforcement of drug control and administration regulation of the country is essential in the overall effort of improving animal health and productivity through the control of protozoan diseases in and around Asella.

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The prevalence and clinico-haematological changes of protozoan diseases in food animals in Alabata, Abeokuta

Cited by 6 publications

References 0 publications

Fractions of Lawsonia inermis Linn leaves reversed the damage caused to major organs involved in diabetic complications by improving their histomorphological appearance in diabetic Wistar rat model

Fractions of Lawsonia inermis Linn leaves reversed the damage caused to major organs involved in diabetic complications by improving their histomorphological appearance in diabetic Wistar rat model

Antiprotozoal Drug Handling and Management Practices in Asella District, Central Oromia, Ethiopia

Antiprotozoal Drugs Handling and Management Practices in Asella District, Central Oromia, Ethiopia

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