The prevalence and correlates of fatigue in older cancer patients

Respini, Daniela; Jacobsen, Paul B.; Thors, Christina; Tralongo, Paolo; Balducci, Lodovico

doi:10.1016/s1040-8428(02)00176-2

Cited by 94 publications

(67 citation statements)

References 27 publications

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“…A strong relationship has been noted in the literature between CRF during treatment and anxiety and depression (5,9,22,34,49,50,(53)(54)(55)(56)(57)(58)(59)(60)(61)(62)(63)(64)(65)(66)(67). In this longitudinal survey demographic variables and factors associated with the tumour and anti-cancer treatment were unrelated to the fatigue.…”

Section: Fatigue During Anti-cancer Treatmentsupporting

confidence: 52%

Fatigue in Gynecological Cancer Patients During and After Anticancer Treatment

Prue

Allen

Gracey

et al. 2010

Journal of Pain and Symptom Management

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We recommend you cite the published version. The publisher's URL is http://dx.doi.org/10. 1016/j.jpainsymman.2009.06.011 Refereed: No (no note) Disclaimer UWE has obtained warranties from all depositors as to their title in the material deposited and as to their right to deposit such material. UWE makes no representation or warranties of commercial utility, title, or fitness for a particular purpose or any other warranty, express or implied in respect of any material deposited.UWE makes no representation that the use of the materials will not infringe any patent, copyright, trademark or other property or proprietary rights. UWE accepts no liability for any infringement of intellectual property rights in any material deposited but will remove such material from public view pending investigation in the event of an allegation of any such infringement. Re: FATIGUE IN GYNAECOLOGICAL CANCER PATIENTS DURING AND AFTER ANTI-CANCER TREATMENTFollowing your recommendation we have merged the original submissions to you journal and have now submitted the manuscript on the above topic via the online submission system for your consideration.All authors have read and approved both manuscripts. I would be most grateful if you could copy all correspondence to my co-authors: Dr Fiona Cramp; fiona.cramp@uwe.ac.uk and Dr Jacqueline Gracey; jh.gracey@ulster.ac.uk as I am currently on maternity leave and may not be able to access my emails on a regular basis. I hope that you will consider the enclosed manuscript for publication in the Journal of Pain and Symptom Management and look forward to receiving your response.

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Section: Fatigue During Anti-cancer Treatmentsupporting

confidence: 52%

Fatigue in Gynecological Cancer Patients During and After Anticancer Treatment

Prue

Allen

Gracey

et al. 2010

Journal of Pain and Symptom Management

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“…Patients from older age groups typically present with existing physiologic decline and coexisting medical conditions; thus, symptom management can be a considerable challenge. 29,56,57 In this study, we have found that those with more comorbidities were at a greater risk for pain. This is not surprising because chronic diseases such as cancer,51 arthritis,42 diabetes,26,44 and cardiovascular disease41 are associated with painful conditions.…”

Section: Discussionmentioning

confidence: 54%

Pain in Aging Community-Dwelling Adults in the United States: Non-Hispanic Whites, Non-Hispanic Blacks, and Hispanics

Reyes‐Gibby

Aday

Todd

et al. 2007

The Journal of Pain

149

134

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Racial and ethnic disparities in healthcare persist in the U.S. Although pain is one of the most prevalent and disabling symptoms of disease, only a few studies have assessed disparities in pain in large racially and ethnically diverse, middle-to late aged community samples, thus limiting the generalizability of study findings in broader populations. With data from the 2000 Health and Retirement Study, we assessed the prevalence and impact of pain in a community sample of aging (≥51 years old) non-Hispanic whites (n = 11,021), non-Hispanic blacks (n = 1,804), and Hispanics (n = 952) in the U.S. Pain, pain severity, activity limitation as a result of pain, comorbid conditions, and sociodemographic variables were assessed. Results showed that pain prevalence was 28%, and 17% of the sample reported activity limitation as a result of pain. Non-Hispanic blacks (odds ratio [OR], 1.78; 99% confidence interval [CI], 1.33-2.37) and Hispanics (OR, 1.80; 99% CI, 1.26-2.56) had higher risk for severe pain compared with non-Hispanic whites. Analyses of respondents with pain (n = 3,811) showed that having chronic diseases (2 comorbid conditions, OR, 1.5; 99% CI, 1.09-2.17), psychological distress (OR, 1.99; 99% CI, 1.54-2.43), being a Medicaid recipient (OR, 1.63; 99% CI, 1.17-2.25), and lower educational level (OR, 1.45; 99% CI, 1.14-1.85) were significant predictors for severe pain and helped to explain racial/ethnic differences in pain severity.Perspective-This study, which used a large racially and ethnically diverse community sample, provided empirical evidence that racial/ethnic difference in pain severity in aging community adults in the U.S. can be accounted for by differential vulnerability in terms of chronic disease, socioeconomic conditions, and access to care. KeywordsPain; disparities; aging; epidemiology; race; ethnicity Disparities in healthcare persist for racial and ethnic minorities in the United States. 26,50, 63 Racial/ethnic minorities are at a higher risk for poorer health and shorter survival,18,22, 31 have poorer access to healthcare services,33,52 and have lower quality of healthcare.4,25 Despite the fact that pain is one of the most frequent and devastating symptoms of disease, studies on racial/ethnic differences in pain are limited.11,39,40 Most studies of racial and ethnic disparities in healthcare come from studies of diseases such as cardiovascular diseases,9,17, 34 renal diseases,12,24 cancer,10,49,62 In this study, we describe the prevalence and impact of pain in a racially and ethnically diverse, nationally representative sample of middle-to late-aged adults (older than 50 years) in the United States. Studies show that although the pattern of pain prevalence in older people is unclear,28,35 overall, aging populations are at increased risk for pain.14,58,59,74 It is generally accepted that increased pathologic load is an overriding factor contributing to increased pain complaint with advancing age,35 with older adults at a greater risk for diseases that cause pain, such as arthriti...

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“…Patients from older age groups typically present with existing physiologic decline and coexisting medical conditions when diagnosed with cancer; thus, symptom management can be a considerable challenge. 43,47,49 In fact, we have found that a higher proportion of those with a history of cancer have more coexisting medical conditions, suggesting that the burden of illness overall is greater for those with cancer. Yabroff et al 50 found in a large national sample of adults that the burden of illness is greater for those with cancer relative to sex-and agematched control subjects.…”

Section: Discussionmentioning

confidence: 82%

Pain, Depression, and Fatigue in Community-Dwelling Adults With and Without a History of Cancer

Reyes‐Gibby

Aday

Anderson

et al. 2006

Journal of Pain and Symptom Management

110

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The State of the Science Report by the National Cancer Institute on Symptom Management in Cancer identified gaps in understanding the epidemiology of pain, depression, and fatigue, and called for studies that will identify the extent of risk for these symptoms among those with cancer relative to other populations. Using year 2000 data from the Health and Retirement Study, a survey of a nationally representative sample of adults aged ≥50, we evaluated whether respondents with a history of cancer had excess risk for pain, depression, and fatigue compared to those without a history of cancer. We also compared clustering/co-occurrence of symptoms. Controlling for the confounding effects of comorbidities, sociodemographic, and access to care factors, respondents with a history of cancer had higher risk for fatigue (OR = 1.45; 95%CI = 1.29,1.63), depression (OR = 1.21; 95%CI = 1.06,1.37), and pain (OR = 1.15; 95%CI = 1.03,1.28). Symptom clusters were also more prevalent among those with a history of cancer (P < 0.001), with the pain-depression-fatigue cluster as most prevalent.

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The prevalence and correlates of fatigue in older cancer patients

Cited by 94 publications

References 27 publications

Fatigue in Gynecological Cancer Patients During and After Anticancer Treatment

Fatigue in Gynecological Cancer Patients During and After Anticancer Treatment

Pain in Aging Community-Dwelling Adults in the United States: Non-Hispanic Whites, Non-Hispanic Blacks, and Hispanics

Pain, Depression, and Fatigue in Community-Dwelling Adults With and Without a History of Cancer

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