The Prevalence and Impact of Chronic Pain with Neuropathic Pain Symptoms in the General Population

Toth, Cory; Lander, Janice; Wiebe, Samuel

doi:10.1111/j.1526-4637.2009.00655.x

Cited by 183 publications

(167 citation statements)

References 32 publications

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“…Indeed, the overall prevalences of neuropathy and seizures in the present cohort were substantially greater than in the general Canadian population (6.3% and 0.6%). 21,22 The occurrence of neurocognitive impairment herein was comparable to the general population who were 20 years older than the current study group. 21 However, the prevalence of DSP and HAND was lower than in the pre-cART era and consistent with published reports.…”

Section: Ratio Of Aids-related Death In Patients With Hiv/aids With Nsupporting

confidence: 67%

Neurologic disease burden in treated HIV/AIDS predicts survival

Vivithanaporn¹,

Heo²,

Gamble³

et al. 2010

Neurology

194

143

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Section: Ratio Of Aids-related Death In Patients With Hiv/aids With Nsupporting

confidence: 67%

Neurologic disease burden in treated HIV/AIDS predicts survival

Vivithanaporn¹,

Heo²,

Gamble³

et al. 2010

Neurology

194

143

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“…However, traumatic peripheral nerve injuries, excluding amputation injuries, are not frequently included in the neuropathic pain literature, and there have been few reports of patients with peripheral nerve injuries included among other more common etiologies. [31][32][33][34][35] In a literature review by Jensen et al, 32 neuropathic pain was negatively associated with health-related quality of life, and stronger associations were demonstrated when pain-specific measures were compared to more generic measures. Numerous etiologies were included in Jensen et al's review, and there was no differentiation between types of lesions.…”

Section: Discussionmentioning

confidence: 99%

Neuropathic Pain in Patients with Upper-Extremity Nerve Injury

Novak

Katz²

2010

Physiotherapy Canada

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Purpose: The purpose of this review was to present an analysis of the literature of the outcome studies reported in patients following traumatic upperextremity (UE) nerve injuries (excluding amputation), to assess the presence of an association between neuropathic pain and outcome in patients following traumatic UE nerve injuries, and to provide recommendations for inclusion of more comprehensive outcome measures by clinicians who treat these patients. Summary of Key Points: A Medline and CINAHL literature search retrieved 48 articles. This review identified very few studies of patients with peripheral nerve injury that reported neuropathic pain. When pain was reported, visual analogue or numeric rating scales were most frequently used; standardized questionnaires measuring pain or psychosocial function were rarely administered. Recent evidence shows substantial long-term disability and pain in patients following peripheral nerve injury. Recommendation: To better understand neuropathic pain in patients following peripheral nerve injury, future outcome studies should include valid, reliable measures of physical impairment, pain, disability, health-related quality of life, and psychosocial functioning.Key Words: literature review, nerve injury, neuropathic pain, outcome Novak CB, Katz J. Neuropathic pain in patients with upper-extremity nerve injury. Physiother Can. 2010;62:190-201. RÉ SUMÉObjectif : L'objectif de cette revue é tait de pré senter une analyse de la documentation portant sur les é tudes ré pertorié es concernant les patients aux prises avec des lé sions nerveuses traumatiques des membres supé rieurs (excluant l'amputation), d'é valuer la pré sence d'un lien entre la douleur né vropathique et les ré sultats attendus chez les patients à la suite de lé sions nerveuses traumatiques des membres supé rieurs et de formuler des recommandations en vue d'inclure le recours à des mesures de rendement plus complè tes par les cliniciens traitant ces patients. Ré sumé des principales é tapes : Une recherche documentaire dans Medline et dans CINAHL a permis de ré pertorier 48 articles. Cette recherche a permis de constater que parmi les patients souffrant de lé sions nerveuses pé riphé riques é tudié s, trè s peu avaient signalé des douleurs né vropathiques. Lorsque de la douleur é tait signalé e, des é chelles de mesure numé riques ou des é chelles visuelles analogues é taient utilisé es le plus fré quemment et l'on faisait rarement appel à des questionnaires normalisé s pour é valuer la douleur ou la fonction psychosociale. Des faits ré cents dé montrent qu'à la suite d'une lé sion nerveuse pé riphé rique, de nombreux patients ressentent de la douleur et souffrent d'une incapacité à long terme. Recommandation : Pour mieux comprendre la douleur né vropathique qui survient à la suite d'une lé sion nerveuse pé riphé rique, les prochaines é tudes devraient inclure des mesures valables et fiables des dé ficiences physiques, de la douleur, des incapacité s, de la qualité de vie lié e à la santé et à la fonctio...

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“…NP is common, with estimation in the general population ranging from 3% to 18%, depended on the methods used to classify individuals as having this symptom [3]. Moreover, a lot of evidences support the conclusion that NP has a significant negative impact on the quality of life [4].…”

Section: Introductionmentioning

confidence: 99%

Transcranial Direct Current Stimulation in Neuropathic Pain

Ngernyam¹

2014

J Pain Relief

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Neuropathic pain (NP) is one of the most common problems contributing to suffering and disability worldwide. Unfortunately, NP is also largely refractory to treatments, with a large number of patients continuing to report significant pain even when they are receiving recommended medications and physical therapy. Thus, there remains an urgent need for additional effective treatments. In recent years, nonpharmacologic brain stimulation techniques have emerged as potential therapeutic options. Many of these techniques and procedures -such as transcranial magnetic stimulation, spinal cord stimulation, deep brain stimulation, and motor cortical stimulation -have very limited availability, particularly in developing countries. Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation procedure that has shown promise for effectively treating NP, and also has the potential to be widely available. This review describes tDCS and the tDCS procedures and principles that may be helpful for treating NP. The findings indicate that the analgesic benefits of tDCS can occur both during stimulation and beyond the time of stimulation. The mechanisms of cortical modulation by tDCS may involve various activities in neuronal networks such as increasing glutamine and glutamate under the stimulating electrode, effects on the μ-opioid receptor, and restoration of the defective intracortical inhibition. Additional research is needed to determine (1) the factors that may moderate the efficacy of tDCS, (2) the dose (e.g. number and frequency of treatment sessions) that results in the largest benefits and (3) the long-term effects of tDCS treatment.

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The Prevalence and Impact of Chronic Pain with Neuropathic Pain Symptoms in the General Population

Cited by 183 publications

References 32 publications

Neurologic disease burden in treated HIV/AIDS predicts survival

Neurologic disease burden in treated HIV/AIDS predicts survival

Neuropathic Pain in Patients with Upper-Extremity Nerve Injury

Transcranial Direct Current Stimulation in Neuropathic Pain

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