The Prevalence and Pattern of Cannabis Use Among Patients Attending a Methadone Treatment Clinic in Nairobi, Kenya

Ngarachu, Elizabeth Wambui; Kiburi, Sarah Kanana; Owiti, Frederick; Kangethe, Rachel N.

doi:10.21203/rs.3.rs-927162/v1

Cited by 1 publication

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References 39 publications

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“…Furthermore, previous studies have investigated the prevalence of natural cannabis use in OUD populations. While some show a similar, although somewhat lower prevalence of 15% in positive urine samples ( 21 ), other studies show a higher prevalence of e.g., 58% ( 20 ) and 63% ( 22 ). Differences in the prevalence of cannabis use in this population could be explained by characteristics of the sample such as the country where the studies were conducted.…”

Section: Discussionmentioning

confidence: 88%

Synthetic cannabinoids use in a sample of opioid-use disorder patients

et al. 2022

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Cannabis is the most widely consumed illegal drug in the world and synthetic cannabinoids are increasingly gaining popularity and replacing traditional cannabis. These substances are a type of new psychoactive substance that mimics the cannabis effects but often are more severe. Since, people with opioids use disorder use widely cannabis, they are a population vulnerable to use synthetic cannabinoids. In addition, these substances are not detected by the standard test used in the clinical practice and drug-checking is more common in recreational settings. A cross-sectional study with samples of 301 opioid use disorder individuals was carried out at the addiction care services from Barcelona and Badalona. Urinalysis was performed by high-sensitivity gas chromatography-mass spectrometry (GC-MS) and ultra-high-performance liquid chromatography-high –resolution mass spectrometry (UHPLC-HRMS). Any synthetic cannabinoid was detected in 4.3% of the individuals and in 23% of these samples two or more synthetic cannabinoids were detected. Among the 8 different synthetic cannabinoids detected, most common were JWH-032 and JWH-122. Natural cannabis was detected in the 18.6% of the samples and only in the 0.7% of them THC was identified. Several different synthetic cannabinoids were detected and a non-negligible percentage of natural cannabis was detected among our sample. Our results suggest that the use of synthetic cannabinoids may be related to the avoidance of detection. In the absence of methods for the detection of these substances in clinical practice, there are insufficient data and knowledge making difficult to understand about this phenomenon among opioid use disorder population.

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Section: Discussionmentioning

confidence: 88%