The Prevalence and Risk Factors of Type II Diabetes Mellitus Among Patients with Hepatitis B Virus: A Descriptive Correlational Study

Ziaee, Masood; Sharifzadeh, Gholamreza; Azarkar, Zohreh; Namaei, Mohammad Hasan; Zardast, Mahmoud; Saljoughi, Mahboubeh; Elhamirad, Samira; Ebrahimzadeh, Azadeh

doi:10.5812/modernc.65664

Cited by 3 publications

(2 citation statements)

References 24 publications

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“…Caronia et al (19) and Ozylikan et al (20) proved the high prevalence of diabetes mellitus in patients with hepatitis C. Drakoulis (2002) and Chern (2001) showed that chronic hepatitis C infection could have a diabetogenic effect because hepatitis C increases liver damage caused by the accumulation of excess iron in the liver, and the developed liver dysfunction can be a factor in insulin resistance and impaired glucose tolerance (21,22). A study conducted by Ebrahimzadeh in Esfandiare proved that the prevalence of HBsAg in diabetics was higher than that in non-diabetics (23). These differences can be due to the limited sample size of the current study and the differences in the race and geographical distribution or overall incidence of diabetes mellitus in each region, and also different demographic variables, and even the type of tests and kits.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Frequency Distribution of Diabetes in Hepatitis B and C Patients and Other People in Birjand

et al. 2021

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Background: Diabetes and hepatitis are among the most common diseases in the world. Hepatitis C virus leads to extra-liver manifestations, including endocrine disease and diabetes. The prevalence of hepatitis C and B in diabetic patients and the prevalence of diabetes in hepatitis C and B patients are higher than those in normal populations, and if each is added to the other, the complications will be more and the consequences will be worse. Objectives: This study aimed to compare the frequency distribution of diabetes and serum lipid levels in hepatitis B and C patients and other people. Methods: In this retrospective case-control study, 80 patients with hepatitis B and C and 160 patients without hepatitis were included. In both groups, those with two glucose levels above 126 mg/dL were considered as diabetic subjects. Also, the tests for factors such as cholesterol, TG, LDL, HbA1c, HDL, and liver ultrasonography were performed for patients. Data were collected and entered into SPSS 23 software and analyzed using descriptive statistical tests (t test and chi-square or Fisher's exact test) at a significance level of α = 0.05. Results: A total of 240 patients [80 cases (hepatitis B or C positive) and 160 controls] were enrolled. Of them, 46.3% were females and most of them were in the age range of 45-55 years. Besides, 14 (5.8%) subjects had high fasting blood glucose levels of more than 126 mg/dl twice, and were considered to have diabetes. Among them, four (5.0%) cases (all having hepatitis B) and 10 (6.3%) controls were diabetics. Statistical analysis showed no significant difference in the mean serum lipids of cholesterol and LDL between the case and control groups (P < 0.1) but there was a significant association between HDL and TG in both groups (P = 0.02). Conclusions: All patients with hepatitis B and C should be screened for diabetes, and in addition to fasting blood glucose, we suggest that HbA1c be measured to confirm or rule out diabetes.

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Section: Discussionmentioning

confidence: 99%

Comparison of Frequency Distribution of Diabetes in Hepatitis B and C Patients and Other People in Birjand

et al. 2021

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“…A total of 20 (12,13,14,15,16,17,18,19,21,22,23,24,25,26,27,28,29,30,31,32) studies were analyzed with 245,468,411 subjects were enrolled this study which were published between 2003 to 2020. In which divided into two subgroups, 12,982,158 patients with HBV infected group and 232,486,253 patients in non infected HBV groups.…”

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confidence: 99%

Hepatitis B Virus Infection as a Risk Factor for Developing Diabetes Mellitus: A Meta-Analysis of a Large Observational Studies

Sari

Agdelina

Bahri

et al. 2021

InaJGHE

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Background: There are a lot of theories about how Hepatitis B Virus (HBV) infection affects many diseases, one of them is Diabetes Mellitus (DM). However, the relation remains controversial between DM and HBV as an infection. This study aims to evaluate HBV infection as a risk factor for developing DM.Method: A systematic review was performed using medical search engines such as Pubmed, ScienceDirect and GoogleScholar. References until February 2021 that met the inclusion criteria were reviewed. The primary outcome was the prevalence of DM. Authors also perform Subgroup analyses based on study type. The extracted data were analyzed using RevMan 5.4 application.Results: A total of 20 studies were analyzed with 245,468,411 subjects included. In which divided into two groups, patients with HBV infected group and non infected HBV group. Authors found that there is a statistically difference between patients with HBV infected groups and non infected HBV groups on the primary outcome which is the prevalence of DM (OR 1.24; 95% CI, 1.10-1.41; p = 0.0006). Authors also found the same results based on study type both in case-control (OR = 1.76; 95% CI: 1.08-2.85; p = 0.02) and cross-sectional (OR = 1.40; 95% CI: 1.05-1.85; p = 0.02) studies. Meanwhile in Cohort studies the results show no statistically significant difference between the two groups (OR = 1.07; 95% CI: 0.87-1.33; p = 0.52). Conclusion: HBV infected patients have a higher risk of developing DM than patients without HBV infection.

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Prevalence and intensity of cigarette smoking in Iranian households: measurement of socioeconomic inequality

Safari‐Faramani

Dizaj

Amini

et al. 2023

Journal of Substance Use

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The Prevalence and Risk Factors of Type II Diabetes Mellitus Among Patients with Hepatitis B Virus: A Descriptive Correlational Study

Cited by 3 publications

References 24 publications

Comparison of Frequency Distribution of Diabetes in Hepatitis B and C Patients and Other People in Birjand

Comparison of Frequency Distribution of Diabetes in Hepatitis B and C Patients and Other People in Birjand

Hepatitis B Virus Infection as a Risk Factor for Developing Diabetes Mellitus: A Meta-Analysis of a Large Observational Studies

Prevalence and intensity of cigarette smoking in Iranian households: measurement of socioeconomic inequality

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