The Prevalence and Severity of Sickle Cell Disease in Amravati District of Maharashtra

Ahmad, Maryam; Gupta, Hariom; Shinde, D.S.; Ruparel, N. D

doi:10.5530/ijopp.11.4.42

Cited by 1 publication

(1 citation statement)

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“…According to Table 1, the most common blood group present in βthalassemia patients was O (34.6%), followed by B (29%), and A (25%), while the least common blood group was AB (11.4%). The ABO blood group pattern observed in the current study was O>B>A>AB, which is similar to the past studies [14][15][16][17]. It was found that Rh factor was present in most of the β-thalassemia patients (94.2%) and absent only in a few (5.8%) patients.…”

Section: Discussionsupporting

confidence: 90%

Association of β-Thalassemia and its Types with ABO and Rh Blood Groups in Lahore, Pakistan

Waheed,

Rizvi,

Mubarak

2023

BioSci Rev.

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The current study aims to determine the relationship of ß-thalassemia and its types (major, minor, intermedia) with ABO and Rh blood groups in Lahore, Pakistan. It is an observational study in which ABO and Rh blood grouping of 711 β-thalassemia patients was performed (with their consent). Blood grouping was performed through forward and reverse grouping using tube method. The observed ABO blood group pattern in both genders was O>B>A>AB. It was found that the overall frequency of O and A blood groups was higher in female patients, while the frequency of B and AB blood groups was higher in male patients, although the difference was non-significant. However, a significant difference was observed in the relationship between gender and Rh factor. Most patients of β-thalassemia suffered from the type β-thalassemia major (48%), followed by patients suffering from β-thalassemia minor (44%) and β-thalassemia intermedia (8%). Overall, patients with AB blood group mostly suffered from β-thalassemia major, while patients with β-thalassemia minor and β-thalassemia intermedia had the highest frequency of blood group B. It was concluded that ß-thalassemia patients have a higher frequency of O+ blood group and the lowest frequency of AB- blood group. Moreover, a significant difference was seen between male and female patients with respect to Rh blood group. However, no significant difference (p > 0.05) was found in the distribution of ABO and Rh blood groups corresponding to β-thalassemia types.

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Section: Discussionsupporting

confidence: 90%