The Prevalence, Awareness and Treatment of High Low Density Lipoprotein-Cholesterol in Korean Adults Without Coronary Heart Diseases - The Third Korea National Health and Nutrition Examination Survey, 2005 -

Abstract

Background and Objectives The purpose of this study was to estimate the prevalence, awareness and treatment of high low density lipoprotein-cholesterol (LDL-C) level in Korean adults without coronary heart disease. Subjects and Methods National representative cross-sectional surveys, data of 5248 Korean adults (2246 men and 3002 women) aged between 20 and 79 years from the Third Korea National Health and Nutrition Examination Survey (KNHANES III, 2005) was used. High LDL-C level was defined with the risk prediction algorithm published by the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III). Results The prevalence of the Korean adults with high LDL-C level who need therapeutic lifestyle changes was 19.9%, treatment with lipid-lowing medication was 2.1% and awareness of this condition was 7.9%. Meanwhile, the prevalence of the Korean with very high LDL-C level who should be considered for drug therapy was 13.5%, treatment with lipid-lowing medication was 2.7% and awareness of this condition was 8.1%. Overall, 47.9% (60.3% in male and 39.1% in female) of participants had a single lipid disorder (high LDL-C, high triglycerides: ≥200 mg/dL, low high density lipoprotein-cholesterol: <40 mg/dL), whereas 15.5% (23.5% in male and 9.7% in female) had at least two. Only 1.9% (2.8% in male and 1.2% in female) of all participants had all three lipid abnormalities as defined. Conclusion These findings indicate that continuous efforts are needed to increase awareness and treatment of high LDL-C level in our population to prevent cardiovascular disease.

Prevalence of Dyslipidemia and Management in the Thai Population, National Health Examination Survey IV, 2009

“…The current cholesterol levels of the Thai population are comparable to the levels in the U.S. in 1988–1994 [23]. The level of HDL-C in the Thai population is slightly lower than that of the Korean population reported in 2006 and 2012 [9, 24]. The Korea health survey reported that the levels of TC, LDL-C, HDL-C, and triglycerides were 184.7, 114, 45.2, and 135.2 mg/dL, respectively, which were more favorable than what was found in the Thai population in the present study [9].…”

Association betweenCDH13Variants and Cardiometabolic and Vascular Phenotypes in a Korean Population

“…Asian people exhibit the characteristic phenotype of adiposity5 and adiposity-related lipid6 or vascular traits 5. However, studies on genetic basis of these relationships have been insufficient in this population.…”

Achievement of LDL-C Targets Defined by ESC/EAS (2011) Guidelines in Risk-Stratified Korean Patients with Dyslipidemia Receiving Lipid-Modifying Treatments

“…However, in recent years, the incidence of hypercholesterolemia and elevated LDL-cholesterol (LDL-C) levels has been increasing in parallel, without any decrease in hypertriglyceridemia or hypo-HDL-cholesterolemia [8]. Further KNHANES database has shown that approximately 10.0% of Korean adults have LDL-C levels that needed to be pharmacologically lowered, and 19.9% have LDL-C levels that needed therapeutic lifestyle modifications [9]. Consequently, dyslipidemia stands to substantially increase the cardiovascular (CV) risk in the Korean population and needs to be considered as a major health concern in the Korean setting.…”

“…A recent study in Korean real-world practice has demonstrated good compliance for at least 18 months in patients who had been started with statins at the fixed doses [22]; however, the study was performed at a single institution and lacks generalizability. Moreover, the indices of metabolic syndrome in Korea have historically been TG and HDL-C [9], hence it is not possible to infer LDL-C levels in the general population from the KNHANES database [23].…”