The prevalence of aspirin intolerant asthma (AIA) in Australian asthmatic patients

Vally, Hassan; Taylor, M.L.; Thompson, Philip J.

doi:10.1136/thorax.57.7.569

Cited by 131 publications

(103 citation statements)

References 24 publications

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“…asthmatics from 4.3% to 11% (9)(10)(11). In the last metaanalysis the prevalence of AIA in an adult population of asthmatics was reported to be as high as 21% when provocation tests were used for diagnosis (12).…”

mentioning

confidence: 99%

EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity

Niżankowska‐Mogilnicka

Bochenek

Mastalerz

et al. 2007

Allergy

361

327

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Aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs) are among the most common causes of adverse drug reactions. Majority of them are of the hypersensitivity type. The two frequent clinical presentations of aspirin hypersensitivity are: aspirin‐induced bronchial asthma/rhinosinusitis (AIA/R) and aspirin‐induced urticaria/angioedema (AIU). The decisive diagnosis is based on provocation tests with aspirin, as the in vitro test does not hold diagnostic value as yet. Detailed protocols of oral, bronchial and nasal aspirin provocation tests are presented. Indications, contraindications for the tests, the rules of drug withdrawal and equipment are reviewed. Patient supervision and interpretations of the tests are proposed.

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mentioning

confidence: 99%

EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity

Niżankowska‐Mogilnicka

Bochenek

Mastalerz

et al. 2007

Allergy

361

327

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“…2 Common triggers include: cockroaches, fur/haired animals like cats and dogs, pollen, molds 15 , domestic mites, indoor and outdoor pollutants 15,16 , viral infections, drugs such as noncardio-selective beta blockers, ACE inhibitors, aspirin and other non-steroidal anti-inflammatory drugs. 17,18,19 Patients with asthma should be educated about other diseases that worsen asthma especially allergic rhinitis. 20,21 In one study at Mulago hospital assessing the level of asthma control, presence of rhinitis symptoms was associated with a 5 fold increase in poor asthma control.…”

Section: Asthma Management Patient Education and Trigger Avoidancementioning

confidence: 99%

Guidance on the diagnosis and management of asthma among adults in resource limited settings

Kirenga¹,

Schwartz²,

Jong³

et al. 2016

Afr H. Sci.

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Background: Optimal management of asthma in resource limited settings is hindered by lack of resources, making it difficult for health providers to adhere to international guidelines. The purpose of this review is to identify steps for asthma diagnosis and management in resource limited settings. Methods: Review of international asthma guidelines and other published studies on diagnosis and management of asthma. Results: We establish that clinical diagnosis of asthma can be made if recurrent respiratory symptoms especially current wheeze or wheeze in the last 12 months are present. Presence of a trigger, other allergic diseases, personal or family history of asthma; clinical improvement and increase in the peak flow and forced expiratory volume in one second of ≥12% after salbutamol administration increases the likelihood of asthma. At diagnosis severity grading, patient education, removal or reduction of trigger should be done. Follow up 2-6 weeks and assessment of control during therapy is essential. Therapy should be adjusted up or down depending on control levels. Patients should be instructed to increase the frequency of their bronchodilators and/or steroids therapy when they start to experience worsening symptoms. Conclusion: Good quality asthma care can be achieved in resource limited settings by use of clinical data and simple tests.

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“…[2][3][4] Asthma is not always present and thus the preferred terminology AERD. Other characteristics include the less common association with atopy, 3,5 hypereosinophilia, and a tendency to develop de novo in adulthood. 3,[5][6][7] Aspirin hypersensitivity is found in as many as 10%-20% of adult asthmatics and up to 30% of asthmatics with nasal polyposis.…”

mentioning

confidence: 99%

“…Other characteristics include the less common association with atopy, 3,5 hypereosinophilia, and a tendency to develop de novo in adulthood. 3,[5][6][7] Aspirin hypersensitivity is found in as many as 10%-20% of adult asthmatics and up to 30% of asthmatics with nasal polyposis. 5,8 When asthma is present in this disorder, it often becomes severe and is associated with aggressive airway remodeling.…”

mentioning

confidence: 99%

“…3,[5][6][7] Aspirin hypersensitivity is found in as many as 10%-20% of adult asthmatics and up to 30% of asthmatics with nasal polyposis. 5,8 When asthma is present in this disorder, it often becomes severe and is associated with aggressive airway remodeling. 9 Similarly, the sinusitis present in this disorder is often severe and associated with complete or near complete sinus opacification.…”

mentioning

confidence: 99%

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Factors Driving the Aspirin Exacerbated Respiratory Disease Phenotype

Steinke

Borish

2015

Am J Rhinol�Allergy

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The prevalence of aspirin intolerant asthma (AIA) in Australian asthmatic patients

Cited by 131 publications

References 24 publications

EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity

EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity

Guidance on the diagnosis and management of asthma among adults in resource limited settings

Factors Driving the Aspirin Exacerbated Respiratory Disease Phenotype

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