The prevalence of bruxism and oral parafunction activities among Israeli juveniles with autism spectrum disorder: A preliminary study during the COVID-19 pandemic

Winocur-Arias, Orit; Amitai, Bat-Chen; Winocur, Efraim; Shmuly, Tom; Grinstein Koren, Osnat; Reiter, Shoshana

doi:10.1080/08869634.2023.2277618

Cited by 1 publication

(1 citation statement)

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“…Winocur's research dismisses a definite connection between ASD and TMD, asserting that the prevalence of TMD-related pain is low in ASD patients. However, due to the complexity of pain assessment in ASD patients, further research is needed to validate this perspective (Winocur-Arias et al, 2023). This research conclusion aligns with ours, as no causal relationship was found between ASD and TMD.…”

Section: Discussionsupporting

confidence: 84%

Neurodevelopmental disorders as a risk factor for temporomandibular disorder: evidence from Mendelian randomization studies

Wu,

Li,

Cui

et al. 2024

Front. Genet.

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Objective: This study aims to clarify the incidence rate of temporomandibular joint disease in patients with mental disorders.Methods: Data extracted from the Psychiatric Genomics Consortium and FinnGen databases employed the Mendelian Randomization (MR) method to assess the associations of three neurodevelopmental disorders (NDDs)—Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), and Tourette’s Disorder (TD)—as exposure factors with Temporomandibular Disorder (TMD). The analysis used a two-sample MR design, employing the Inverse Variance Weighted (IVW) method to evaluate the relationships between these disorders and Temporomandibular Disorder. Sensitivity analysis and heterogeneity assessments were conducted. Potential confounding factors like low birth weight, childhood obesity, and body mass index were controlled for.Results: The study found that ADHD significantly increased the risks for TMD (OR = 1.2342, 95%CI (1.1448–1.3307), p < 0.00001), TMD (including avohilmo) (OR = 1.1244, 95%CI (1.0643–1.1880), p = 0.00003), TMD-related pain (OR = 1.1590, 95%CI (1.0964–1.2252), p < 0.00001), and TMD-related muscular pain associated with fibromyalgia (OR = 1.1815, 95%CI (1.1133–1.2538), p < 0.00001), while other disorders did not show significant causal relationships.Conclusion: This study reveals the elevated risk of various TMD aspects due to ADHD. Furthermore, we discuss the link between low vitamin D levels ADHD and TMD. Future research should address these limitations and delve further into the complex interactions between ADHD, ASD, TD, and TMD.

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Section: Discussionsupporting

confidence: 84%