The prevalence of diagnosed obsessive compulsive disorder and associated comorbidities: A population-based Canadian study

Osland, Sydney; Arnold, Paul; Pringsheim, Tamara

doi:10.1016/j.psychres.2018.07.018

Cited by 61 publications

(37 citation statements)

References 25 publications

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“…This finding was consistent with other epidemiological studies. 4,41 While we did not find a significant gender difference in OCD prevalence among respondents with lifetime OCD, it was more likely to be associated with female gender among those with 12-month disorder. While a number of genetic and environmental factors are theorised to be associated with OCD, studies have identified an association with key reproductive events in women including menarche, pregnancy, postpartum and menopause.…”

Section: Discussioncontrasting

confidence: 69%

Obsessive-Compulsive Disorder in Singapore: Prevalence, Comorbidity, Quality of Life and Social Support

Subramaniam

Abdin

Vaingankar

et al. 2020

Ann Acad Med Singap

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Introduction: Using data from Singapore Mental Health Study 2016 (SMHS 2016), we examined the prevalence of lifetime and 12-month obsessive-compulsive disorder (OCD),its sociodemographics correlates and association with comorbid psychiatric disorders and physical conditions, perceived social support and quality of life. Materials and Methods: The World Mental Health Composite International Diagnostic Interview (version 3.0) was administered by trained interviewers to 6126 residents aged ≥18 years old to assess OCD prevalence and that of other select psychiatric disorders. Details on sociodemographics, perceived social support and health-related quality of life were obtained. Results: Lifetimeand 12-month prevalence of OCD was 3.6% and 2.9%, respectively. Adjusted regression analysis showed that those with OCD had significantly higher odds of major depressive disorder (odds ratio [OR], 5.4), bipolar disorder (OR, 8.9), generalised anxiety disorder (OR, 7.3) and alcohol abuse (OR, 2.7). OCD was significantly associated with suicidal ideation and suicidality (OR, 5.1). OCD subjects also had higher odds of chronic pain (OR, 2.4) and diabetes (OR, 3.1). Finally, OCD subjects had lower mean mental composite summary scores than controls (respondents without any of the psychiatric disorders and physical conditions included in SMHS 2016) and those with other lifetime psychiatric disorders and physical conditions. Conclusion: OCD prevalence in Singapore is high. Most people with OCD do not seek treatment despite experiencing significant comorbidity and loss of quality of life. Key words: Composite International Diagnostic Interview, Epidemiology, Multi-ethnic, Psychiatric disorder, Survey

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Section: Discussioncontrasting

confidence: 69%

Obsessive-Compulsive Disorder in Singapore: Prevalence, Comorbidity, Quality of Life and Social Support

Subramaniam

Abdin

Vaingankar

et al. 2020

Ann Acad Med Singap

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“…The study, which was based on semi-structured clinical interviews administered by physicians with experience in mental health, found lower prevalence rates of OCD than the recent WHO epidemiological survey (8). Our results were closer to other studies conducted since the 1980s, including those relying on lay interviewers and structured interviews (3,5,(27)(28)(29)(30)(31), although caution is needed when comparing these surveys on account of methodological differences.…”

Section: Discussionsupporting

confidence: 68%

The Burden of Comorbidity Between Bipolar Spectrum and Obsessive-Compulsive Disorder in an Italian Community Survey

et al. 2020

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Background: The impact of the comorbidity between Obsessive-Compulsive Disorder (OCD) and Bipolar Disorder Spectrum (BDS) remains to be clarified. The objective of this study was to examine the lifetime prevalence of OCD, the strength of the association of OCD with comorbid BDS and the role of comorbidity of OCD with BDS in the impairment of health-related quality of life (HRQoL) in an Italian community survey. Methods: The study is a community survey. The sample (N = 2,267; women: 55.3%) was randomly selected after stratification by sex and four age groups from the municipal records of the adult population of one urban, one suburban, and at least one rural area in six Italian regions. Physicians using a semi-structured interview (Advanced Tools and Neuropsychiatric Assessment Schedule, ANTAS-SCID) made Diagnostic and Statistical Manual of Mental Disorders-4th revision (DSM-IV) diagnoses of OCD, Major Depressive Disorder (MDD) and Bipolar Disorder (BD). HR-QoL was measured by the Health Survey Short Form (SF-12). Lifetime Hypomania and subthreshold hypomania were screened by the Mood Disorder Questionnaire (MDQ). BDS was defined as the sum of people shown to be positive for hypomania by the MDQ-with or without a mood disorder diagnosis-plus people with a BD-DSMIV diagnosis even if negative for hypomania at the MDQ. Results: Overall, 44 subjects were diagnosed with OCD, 6 with MDD and 1 with BD. The lifetime prevalence of OCD was 1.8% in men (n = 18) and 2.0% in women (n = 26). MDD with lifetime subthreshold hypomania (i.e., people screened positive at the MDQ, even without diagnosed mania or hypomania at the interview) was associated with OCD (OR = 18.15, CI 95% 2.45-103.67); MDD without subthreshold hypomania (and screened negative at the MDQ) was not (OR = 2.33, CI 95% 0.69-7.01). People with BDS Carta et al. Bipolar Spectrum and Obsessive-Compulsive Disorders were strongly associated with OCD (OR = 10.5, CI 95% 4.90-12.16,). People with OCD and BDS showed significantly poorer HR-QoL than people with OCD without BDS (F = 9.492; P < 0.003). Discussion: The study found a strong association between BDS and OCD. BDS comorbid with OCD was associated with more severe impairment of HR-QoL than OCD without comorbid BDS. Identification of symptoms of hypomania, including subthreshold symptoms, may therefore be important in people with OCD as they might predict a course with poorer HR-QoL.

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“…Obsessive-compulsive disorder (OCD) is a common psychiatric disorder characterized by intrusive and unwanted thoughts, images, or urges (obsessions) and repetitive behaviors (compulsions) that function to reduce the distress caused by obsessions. The prevalence of OCD is estimated at 0.75-2.5% of the general population (Fontenelle, Mendlowicz, & Versiani, 2006;Karno, Golding, Sorenson, & Burnam, 1988; Behrang Osland, Arnold, & Pringsheim, 2018;Ruscio, Stein, Chiu, & Kessler, 2010;Torres, Albina et al, 2006;Weissman, Bland, & Canino, 1994).…”

Section: Introductionmentioning

confidence: 99%

OCD symptom severity and comorbid psychiatric diagnoses in a Swedish genetic epidemiological obsessive-compulsive disorder cohort

Mahjani

Reichenberg

et al. 2021

Preprint

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Background: We have established an epidemiological obsessive-compulsive disorder (OCD) cohort in Sweden. Individuals contributed DNA for genotyping and sequencing and also completed a Swedish translation of the Obsessive-Compulsive Inventory-Revised (OCI-R), a self-report questionnaire for assessing the severity and type of symptoms of OCD. This study made use of the OCI-R data to examine the severity and symptom dimensions of OCD as well as comorbidity with other psychiatric disorders. Methods: OCI-R data for 1,134 individuals were available for this study, 1,010 diagnosed with OCD, and 124 diagnosed with chronic tic disorders without OCD used as a comparison group. We first evaluated the psychometric properties of the Swedish translation of the OCI-R. Then, we linked data from the Swedish national registries to access and analyze psychiatric comorbidities of OCD. Results: The Swedish translation of OCI-R demonstrated internal consistency (Cronbach's α = 0.9) and clear agreement with the OCI-R six-factor model. The mean total OCI-R score for females was significantly higher than for males. The most comorbid psychiatric condition to OCD were anxiety disorders (13.6%) and major depression (12%). We observed that individuals with OCD frequently had additional comorbid psychiatric disorders and that the severity of OCD was significantly higher in individuals with at least one additional psychiatric comorbidity compared to individuals with no psychiatric comorbidity. Conclusion: We showed that the Swedish translation of the OCI-R has appropriate psychometric properties. Using an epidemiological framework, we were able to assess the severity and symptom dimensions of OCD and comorbidity with other psychiatric disorders.

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The prevalence of diagnosed obsessive compulsive disorder and associated comorbidities: A population-based Canadian study

Cited by 61 publications

References 25 publications

Obsessive-Compulsive Disorder in Singapore: Prevalence, Comorbidity, Quality of Life and Social Support

Obsessive-Compulsive Disorder in Singapore: Prevalence, Comorbidity, Quality of Life and Social Support

The Burden of Comorbidity Between Bipolar Spectrum and Obsessive-Compulsive Disorder in an Italian Community Survey

OCD symptom severity and comorbid psychiatric diagnoses in a Swedish genetic epidemiological obsessive-compulsive disorder cohort

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